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Genetics

D-Index
63
Citations
13587
World Ranking
2899
National Ranking
1267

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Raymond J. Monnat is affiliated with the University of Washington in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology with a focus on several subfields including Molecular Biology, Biomedical Engineering, Cancer Research, Biophysics, and Oncology.

The main topics covered in their work include Cancer Genomics and Diagnostics, Single-cell and Spatial Transcriptomics, DNA Repair Mechanisms, Cell Image Analysis Techniques, 3D Printing in Biomedical Research, Innovative Microfluidic and Catalytic Techniques Innovation, and Acute Myeloid Leukemia Research.

Key recent papers authored or co-authored by Raymond J. Monnat include:

  • "Tumour predisposition and cancer syndromes as models to study gene-environment interactions", 2020, published in Nature reviews. Cancer
  • "High-throughput, microscope-based sorting to dissect cellular heterogeneity", 2020, published in Molecular Systems Biology
  • "Multiplexed drug testing of tumor slices using a microfluidic platform", 2020, published in npj Precision Oncology
  • "A microfluidic platform for functional testing of cancer drugs on intact tumor slices", 2020, published in Lab on a Chip
  • "Multiplexed drug testing of tumor slices using a microfluidic platform", 2020, published in bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors who collaborated with Raymond J. Monnat include:

  • Guangrong Qin
  • Ilya Shmulevich
  • Pamela S. Becker
  • Lisa F. Horowitz
  • A. D. Rodriguez

Publications are commonly featured in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Computational Biology
  • Nature reviews. Cancer
  • Molecular Systems Biology
  • npj Precision Oncology

Raymond J. Monnat was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2019.

Best Publications

  • Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

    Theo A Knijnenburg;Linghua Wang;Michael T Zimmermann;Nyasha Chambwe

  • Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

    Elijahu Berkovich;Raymond J. Monnat;Michael B. Kastan

  • Mutator phenotype of Werner syndrome is characterized by extensive deletions.

    Ken-Ichiro Fukuchi;George M. Martin;Raymond J. Monnat

  • Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

    Matteo Berti;Arnab Ray Chaudhuri;Saravanabhavan Thangavel;Shivasankari Gomathinayagam

  • Computational redesign of endonuclease DNA binding and cleavage specificity.

    Justin Ashworth;James J. Havranek;Carlos M. Duarte;Django Sussman

  • A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

    Nikolai Windbichler;Miriam Menichelli;Philippos Aris Papathanos;Summer B. Thyme

  • DNA polymerases and human disease

    Lawrence A. Loeb;Raymond J. Monnat

  • Design, Activity, and Structure of a Highly Specific Artificial Endonuclease

    Brett S. Chevalier;Tanja Kortemme;Meggen S. Chadsey;David Baker

  • Werner and Hutchinson–Gilford progeria syndromes: mechanistic basis of human progeroid diseases

    Brian A. Kudlow;Brian K. Kennedy;Raymond J. Monnat

  • DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI.

    Karen E. Flick;Melissa S. Jurica;Melissa S. Jurica;Raymond J. Monnat;Barry L. Stoddard

  • Homologous recombination resolution defect in werner syndrome.

    Yannick Saintigny;Kate Makienko;Cristina Swanson;Mary J. Emond

  • Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions

    Junko Oshima;Julia M. Sidorova;Raymond J. Monnat

  • Spectrum and Risk of Neoplasia in Werner Syndrome: A Systematic Review

    Julia M. Lauper;Alison Krause;Thomas L. Vaughan;Thomas L. Vaughan;Raymond J. Monnat

  • I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

    Gretchen M Argast;Kathryn M Stephens;Mary J Emond;Raymond J Monnat

  • Werner syndrome protein limits MYC-induced cellular senescence.

    Carla Grandori;Kou Juey Wu;Paula Fernandez;Celine Ngouenet

  • Loss of Werner syndrome protein function promotes aberrant mitotic recombination

    Polly R. Prince;Mary J. Emond;Raymond J. Monnat

  • DNA Recognition and Cleavage by the LAGLIDADG Homing Endonuclease I-Cre I

    Melissa S Jurica;Raymond J Monnat;Barry L Stoddard

  • Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI.

    Brett Chevalier;Monique Turmel;Claude Lemieux;Raymond J. Monnat

  • The structure of I-Crel, a group I intron-encoded homing endonuclease.

    Patrick J. Heath;Kathryn M. Stephens;Raymond J. Monnat;Barry L. Stoddard

  • Isolation and characterization of new homing endonuclease specificities at individual target site positions.

    Django Sussman;Meg Chadsey;Steve Fauce;Alex Engel

Frequent Co-Authors

Barry L. Stoddard
Barry L. Stoddard Fred Hutchinson Cancer Research Center
Albert Folch
Albert Folch University of Washington
Junko Oshima
Junko Oshima University of Washington
Lawrence A. Loeb
Lawrence A. Loeb University of Washington
Elihu H. Estey
Elihu H. Estey University of Washington
Nancy Maizels
Nancy Maizels University of Washington
William M. Grady
William M. Grady Fred Hutchinson Cancer Research Center
George M. Martin
George M. Martin University of Washington
David Baker
David Baker University of Washington
Andrew M. Scharenberg
Andrew M. Scharenberg Seattle Children's Hospital

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