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Biology and Biochemistry

D-Index
75
Citations
20706
World Ranking
5297
National Ranking
407

Overview

Peter A. Kiener is affiliated with AstraZeneca in the United Kingdom. Their research primarily spans the fields of Immunology and Microbiology as well as Medicine.

The scientist's work encompasses several subfields, including Immunology, Oncology, and Genetics. Key topics in their research involve CAR-T cell therapy, immunotherapy and immune responses, virus-based gene therapy, and immune cell function and interaction.

Recent publications include:

  • "CUE-101, a Novel E7-pHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies" (2020) in Clinical Cancer Research
  • "Peptide-HLA-based immunotherapeutics platforms for direct modulation of antigen-specific T cells" (2021) in Scientific Reports

Frequent co-authors collaborating with Kiener include Steven N. Quayle, Dharma R. Thapa, Zohra Merazga, Paige Ruthardt, and Jonathan Soriano.

The venues where the scientist's work has most commonly appeared are Clinical Cancer Research and Scientific Reports.

Best Publications

  • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

    Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen

  • Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn)

    William F. Dall'Acqua;Peter A. Kiener;Herren Wu

  • Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

    W C Liles;P A Kiener;J A Ledbetter;A Aruffo

  • MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.

    Roland Kolbeck;Alexander Kozhich;Masamichi Koike;Li Peng

  • A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma

    Geoffrey L Chupp;Chun Geun Lee;Nizar Jarjour;Yun Michael Shim

  • Expression of functional CD40 by vascular endothelial cells.

    Diane Hollenbaugh;Nicole Mischel-Petty;Caroline P. Edwards;Jan C. Simon

  • Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract.

    Herren Wu;David S. Pfarr;Syd Johnson;Yambasu A. Brewah

  • Increasing the Affinity of a Human IgG1 for the Neonatal Fc Receptor: Biological Consequences

    William F. Dall’ Acqua;Robert M. Woods;E. Sally Ward;Susan R. Palaszynski

  • Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes

    P A Kiener;P Moran-Davis;B M Rankin;A F Wahl

  • Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

    Brandon W Higgs;Zheng Liu;Barbara White;Wei Zhu

  • Soluble Fas Ligand Induces Epithelial Cell Apoptosis in Humans with Acute Lung Injury (ARDS)

    G Matute-Bello;W C Liles;K P Steinberg;P A Kiener

  • Soluble CTLA4 molecules and uses thereof

    Peter S. Linsley;Jeffrey A. Ledbetter;Nitin K. Damle;William Brady

  • Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

    William W. Busse;Rohit Katial;David Gossage;Suha Sari

  • Anthracycline conjugates having a novel linker and methods for their production

    Robert S. Greenfield;Gary R. Braslawsky;Lee J. Olech;Takushi Kaneko

  • Type I interferon: potential therapeutic target for psoriasis?

    Yihong Yao;Laura Richman;Chris Morehouse;Melissa de los Reyes

  • Neutralization of interferon‐α/β–inducible genes and downstream effect in a phase I trial of an anti–interferon‐α monoclonal antibody in systemic lupus erythematosus

    Yihong Yao;Laura Richman;Brandon W. Higgs;Christopher A. Morehouse

  • Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization

    Herren Wu;David S. Pfarr;Ying Tang;Ling-Ling An

  • A role for tumour necrosis factor-α, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome

    Geoffrey M. Gersuk;Cassandra Beckham;Michael R. Loken;Peter Kiener

  • Differential Induction of Apoptosis by Fas-Fas Ligand Interactions in Human Monocytes and Macrophages

    Peter A. Kiener;Patricia M. Davis;Gary C. Starling;Christopher Mehlin

  • Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis.

    Ronan J. Walsh;Sek Won Kong;Sek Won Kong;Yihong Yao;Bahija Jallal

Frequent Co-Authors

Herren Wu
Herren Wu AstraZeneca (United Kingdom)
Anthony J. Coyle
Anthony J. Coyle Takeda (United States)
Ronald Herbst
Ronald Herbst Biolojic Design
Michael S. Kinch
Michael S. Kinch Washington University in St. Louis
Jeffrey A. Ledbetter
Jeffrey A. Ledbetter University of Washington
Alejandro Aruffo
Alejandro Aruffo Syngenta (United States)
Roland Kolbeck
Roland Kolbeck AstraZeneca (United Kingdom)
Peter Kufer
Peter Kufer Amgen (United States)
W. Conrad Liles
W. Conrad Liles University of Washington
Thomas F. Tedder
Thomas F. Tedder Duke University

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