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Immunology

D-Index
65
Citations
18285
World Ranking
2817
National Ranking
1332

Overview

Peter Kufer is affiliated with Amgen in the United States and works primarily in the field of Medicine, with a focus on Oncology. Their research encompasses several subfields including Radiology, Nuclear Medicine and Imaging, Biomedical Engineering, Immunology, and Pulmonary and Respiratory Medicine.

Their work centers on key topics such as CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Monoclonal and Polyclonal Antibodies Research, Immunotherapy and Immune Responses, Radiopharmaceutical Chemistry and Applications, Nanowire Synthesis and Applications, and Nanofabrication and Lithography Techniques.

Among their frequent co-authors are Sabine Stienen, Gerhard Zugmaier, Maria-Elisabeth Goebeler, Ralf C. Bargou, and Joachim Wahl.

Peter Kufer has published in several notable journals including Cancer, Cancer Research, Immunotherapy, Clinical Cancer Research, and the Journal of Clinical Oncology.

  • "The BiTE (bispecific T-cell engager) platform: Development and future potential of a targeted immuno-oncology therapy across tumor types," 2020, Cancer
  • "Pasotuxizumab, a Bite ® Immune Therapy for Castration-Resistant Prostate Cancer: Phase I, Dose-Escalation Study Findings," 2020, Immunotherapy
  • "The PSMA-targeting Half-life Extended BiTE Therapy AMG 160 has Potent Antitumor Activity in Preclinical Models of Metastatic Castration-resistant Prostate Cancer," 2021, Clinical Cancer Research
  • "Phase I study of pasotuxizumab (AMG 212/BAY 2010112), a PSMA-targeting BiTE (Bispecific T-cell Engager) immune therapy for metastatic castration-resistant prostate cancer (mCRPC)," 2020, Journal of Clinical Oncology
  • "Abstract ND06: AMG 305, a dual targeting BiTE®molecule with selective activity for solid tumors that co-express CDH3 and MSLN," 2023, Cancer Research

Best Publications

  • Tumor Regression in Cancer Patients by Very Low Doses of a T Cell–Engaging Antibody

    Ralf Bargou;Eugen Leo;Gerhard Zugmaier;Matthias Klinger

  • Targeted Therapy With the T-Cell–Engaging Antibody Blinatumomab of Chemotherapy-Refractory Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia Patients Results in High Response Rate and Prolonged Leukemia-Free Survival

    Max S. Topp;Peter Kufer;Nicola Gökbuget;Mariele Goebeler

  • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity

    Matthias Mack;Gert Riethmuller;Peter Kufer

  • A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.

    Anja Löffler;Peter Kufer;Peter Kufer;Peter Kufer;Ralf Lutterbüse;Ralf Lutterbüse;Ralf Lutterbüse;Florian Zettl;Florian Zettl;Florian Zettl

  • Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab.

    Matthias Klinger;Christian Brandl;Gerhard Zugmaier;Youssef Hijazi

  • Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL

    Max S. Topp;Nicola Gökbuget;Gerhard Zugmaier;Evelyn Degenhard

  • Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody

    Torsten Dreier;Grit Lorenczewski;Christian Brandl;Patrick Hoffmann

  • Novel method for the production of anti-human antigen receptors and uses thereof

    Peter Kufer;Tobias Raum

  • Blinatumomab: a historical perspective.

    Dirk Nagorsen;Peter Kufer;Patrick A. Baeuerle;Ralf Bargou

  • Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells.

    Sonja Offner;Robert Hofmeister;Andrea Romaniuk;Peter Kufer

  • Bispecific T-Cell Engager (BiTE) Antibody Construct Blinatumomab for the Treatment of Patients With Relapsed/Refractory Non-Hodgkin Lymphoma: Final Results From a Phase I Study

    Maria-Elisabeth Goebeler;Stefan Knop;Andreas Viardot;Peter Kufer

  • BiTEs: bispecific antibody constructs with unique anti-tumor activity.

    Evelyn Wolf;Robert Hofmeister;Peter Kufer;Bernd Schlereth

  • MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors.

    Klaus Brischwein;Bernd Schlereth;Benjamin Guller;Carola Steiger

  • CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF

    Bernd Dorken;Gert Riethmuller;Peter Kufer;Ralf Lutterbuse

  • Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.

    A Zippelius;P Kufer;G Honold;M W Köllermann

  • A revival of bispecific antibodies

    Peter Kufer;Ralf Lutterbüse;Patrick A. Baeuerle

  • Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen

    Claudia Bluemel;Susanne Hausmann;Petra Fluhr;Mirnalini Sriskandarajah

  • T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

    Torsten Dreier;Patrick A. Baeuerle;Iduna Fichtner;Michael Grün

  • T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells

    Ralf Lutterbuese;Tobias Raum;Roman Kischel;Patrick Hoffmann

  • BiTE: Teaching antibodies to engage T-cells for cancer therapy.

    Patrick A Baeuerle;Peter Kufer;Ralf Bargou

Frequent Co-Authors

Patrick A. Baeuerle
Patrick A. Baeuerle Cullinan Oncology, Inc.
Gert Riethmüller
Gert Riethmüller Ludwig-Maximilians-Universität München
Hermann Einsele
Hermann Einsele University of Würzburg
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Andreas Wolf
Andreas Wolf Max Planck Society
Peter A. Kiener
Peter A. Kiener AstraZeneca (United Kingdom)
Andreas Mackensen
Andreas Mackensen University of Erlangen-Nuremberg
Oliver G. Ottmann
Oliver G. Ottmann Cardiff University
Dieter Hoelzer
Dieter Hoelzer Goethe University Frankfurt
Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin

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