Bernd Dörken

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Best Publications

• Oncogene-induced senescence as an initial barrier in lymphoma development

  Melanie Braig;Soyoung Lee;Christoph Loddenkemper;Cornelia Rudolph

  1494
  Citations

• Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.

  Andreas Engert;Annette Plütschow;Hans Theodor Eich;Andreas Lohri

  1056
  Citations

• Senescence-associated reprogramming promotes cancer stemness

  Maja Milanovic;Dorothy N. Y. Fan;Dimitri Belenki;J. Henry M. Däbritz

  910
  Citations

• A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes.

  Anja Löffler;Peter Kufer;Peter Kufer;Peter Kufer;Ralf Lutterbüse;Ralf Lutterbüse;Ralf Lutterbüse;Florian Zettl;Florian Zettl;Florian Zettl

  689
  Citations

• Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression.

  Ralf C. Bargou;Karsten Jürchott;Christian Wagener;Stephan Bergmann

  568
  Citations

• Intensified Chemotherapy and Dose-Reduced Involved-Field Radiotherapy in Patients With Early Unfavorable Hodgkin's Lymphoma: Final Analysis of the German Hodgkin Study Group HD11 Trial

  Hans Theodor Eich;Volker Diehl;Helen Görgen;Thomas Pabst

  525
  Citations

• Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB

  Stephan Mathas;Stephan Mathas;Michael Hinz;Ioannis Anagnostopoulos;Daniel Krappmann

  456
  Citations

• Antisense therapy in oncology: new hope for an old idea?

  Ingo Tamm;Bernd Dörken;Gunther Hartmann

  397
  Citations

• Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity

  Michael Hinz;Petra Lemke;Ioannis Anagnostopoulos;Christine Hacker

  387
  Citations

• Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma

  Björn Lamprecht;Korden Walter;Stephan Kreher;Stephan Kreher;Raman Kumar

  373
  Citations

• Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

  Daniel Krappmann;Florian Emmerich;Florian Emmerich;Uwe Kordes;Erika Scharschmidt

  359
  Citations

• Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells

  Florian Emmerich;Martina Meiser;Martina Meiser;Michael Hummel;Michael Hummel;Gudrun Demel;Gudrun Demel

  359
  Citations

• Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

  Michael Hinz;Peter Löser;Peter Löser;Stephan Mathas;Stephan Mathas;Daniel Krappmann;Daniel Krappmann

  333
  Citations

• Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

  Thomas Wieder;Frank Essmann;Frank Essmann;Frank Essmann;Aram Prokop;Aram Prokop;Aram Prokop;Karin Schmelz;Karin Schmelz;Karin Schmelz

  326
  Citations

• Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines

  Stephan Hailfinger;Hendrik Nogai;Christiane Pelzer;Maike Jaworski

  311
  Citations

• Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.

  R C Bargou;C Wagener;K Bommert;M Y Mapara

  277
  Citations

• Time-intensified dexamethasone/cisplatin/cytarabine:an effective salvage therapy with low toxicity in patients with relapsed and refractory Hodgkin’s disease

  A. Josting;C. Rudolph;M. Reiser;M. Mapara

  277
  Citations

• Macrophage inflammatory protein 1-alpha (MIP-1α) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells

  Suzanne Lentzsch;Margarete Gries;Margarete Gries;Martin Janz;Martin Janz;Ralf Bargou;Ralf Bargou

  269
  Citations

• Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.

  Ekkehard Brockstedt;Anke Rickers;Susanne Kostka;Andreas Laubersheimer

  267
  Citations

• Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

  Clarissa von Haefen;Thomas Wieder;Bernd Gillissen;Lilian Stärck

  266
  Citations