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Biology and Biochemistry

D-Index
63
Citations
15649
World Ranking
10137
National Ranking
731

Overview

Daniel Krappmann is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research spans areas primarily within biochemistry, genetics, and molecular biology, with substantial contributions to immunology and microbiology, as well as medicine. Their work engages with subfields including immunology, molecular biology, cancer research, oncology, and cell biology.

The scientific topics addressed by Krappmann often focus on signaling and immune regulation. These include:

  • NF-κB Signaling Pathways
  • Interferon and Immune Responses
  • Immune Cell Function and Interaction
  • Cytokine Signaling Pathways and Interactions
  • Immune Response and Inflammation
  • T-cell and B-cell Immunology
  • Cell Death Mechanisms and Regulation

They have contributed to several recent publications, including the following papers:

  • "Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases," 2020, Molecular Cell
  • "A proteome-scale map of the SARS-CoV-2-human contactome," 2022, Nature Biotechnology
  • "Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation," 2023, Nature Immunology
  • "Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1," 2022, Science Advances
  • "A patent review of MALT1 inhibitors (2013-present)," 2021, Expert Opinion on Therapeutic Patents

Frequent co-authors collaborating with Krappmann comprise:

  • Thomas J. O'Neill (15 joint works)
  • Carina Graß (12 joint works)
  • Thomas Seeholzer (11 joint works)
  • Marie J. Tofaute (6 joint works)
  • Andreas Gewies (6 joint works)

Krappmann's publications are commonly found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 4 publications
  • Frontiers in Immunology with 3 publications
  • Zenodo (CERN European Organization for Nuclear Research) with 3 publications
  • Expert Opinion on Therapeutic Patents with 2 publications
  • Proceedings of the National Academy of Sciences with 2 publications

Best Publications

  • NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition.

    Michael Hinz;Daniel Krappmann;Alexandra Eichten;Andreas Heder

  • Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

    R C Bargou;F Emmerich;D Krappmann;K Bommert

  • Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia.

    Susan A. Slaugenhaupt;Anat Blumenfeld;Sandra P. Gill;Maire Leyne

  • NF-kappaB and the innate immune response.

    Eunice N Hatada;Daniel Krappmann;Claus Scheidereit

  • OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

    Kirstin Keusekotten;Paul Ronald Elliott;Laura Glockner;Berthe Katrine Fiil

  • Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB

    Stephan Mathas;Stephan Mathas;Michael Hinz;Ioannis Anagnostopoulos;Daniel Krappmann

  • High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells

    Ralf C. Bargou;Corinna Leng;Daniel Krappmann;Florian Emmerich

  • The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation.

    F G Wulczyn;D Krappmann;C Scheidereit

  • Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity

    Michael Hinz;Petra Lemke;Ioannis Anagnostopoulos;Christine Hacker

  • Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

    Daniel Krappmann;Florian Emmerich;Florian Emmerich;Uwe Kordes;Erika Scharschmidt

  • Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells

    Florian Emmerich;Martina Meiser;Martina Meiser;Michael Hummel;Michael Hummel;Gudrun Demel;Gudrun Demel

  • Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

    Katharina M. Jeltsch;Desheng Hu;Sven Brenner;Jessica Zöller

  • Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

    Michael Hinz;Peter Löser;Peter Löser;Stephan Mathas;Stephan Mathas;Daniel Krappmann;Daniel Krappmann

  • Purification and characterization of the human elongator complex.

    Nicola A. Hawkes;Gabriel Otero;G. Sebastiaan Winkler;Nick Marshall

  • The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.

    Agnieszka Rybak;Heiko Fuchs;Kamyar Hadian;Lena Smirnova

  • NF‐κB p105 is a target of IκB kinases and controls signal induction of Bcl‐3–p50 complexes

    Vigo Heissmeyer;Daniel Krappmann;F.Gregory Wulczyn;Claus Scheidereit

  • Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells

    Uta Ferch;Bernhard Kloo;Andreas Gewies;Vera Pfänder

  • Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

    Meike Broemer;Daniel Krappmann;Claus Scheidereit

  • A20 Negatively Regulates T Cell Receptor Signaling to NF-κB by Cleaving Malt1 Ubiquitin Chains

    Michael Düwel;Verena Welteke;Andrea Oeckinghaus;Mathijs Baens

  • Parkin Mediates Neuroprotection through Activation of IκB Kinase/Nuclear Factor-κB Signaling

    Iris H. Henn;Lena Bouman;Julia S. Schlehe;Anita Schlierf

Frequent Co-Authors

Claus Scheidereit
Claus Scheidereit Max Delbrück Center for Molecular Medicine
Jürgen Ruland
Jürgen Ruland Technical University of Munich
Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Bernd Dörken
Bernd Dörken Charité - University Medicine Berlin
Marc Schmidt-Supprian
Marc Schmidt-Supprian Technical University of Munich
David Komander
David Komander Walter and Eliza Hall Institute of Medical Research
Reiner Siebert
Reiner Siebert University of Ulm

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