World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
55
Citations
11119
World Ranking
2273
National Ranking
28

Overview

Alain Chariot is affiliated with the Fonds de la Recherche Scientifique - FNRS in Belgium. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology as the main subfield. Additional subfields include immunology, cancer research, oncology, and genetics.

The scientist's work broadly spans topics including RNA modifications and cancer, RNA and protein synthesis mechanisms, RNA research and splicing, interferon and immune responses, ubiquitin and proteasome pathways, cancer-related gene regulation, and cancer-related molecular mechanisms research.

Among the recent papers authored by Alain Chariot are:

  • "Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors," 2021, Nature Cancer
  • "The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage," 2020, Nature Communications
  • "Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate," 2021, Nature Communications
  • "Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization," 2022, The EMBO Journal
  • "Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis," 2021, The Journal of Experimental Medicine

Alain Chariot's frequent coauthors include:

  • Kateryna Shostak
  • Pierre Close
  • Laurent Nguyen
  • Silvia Turchetto
  • Christophe Desmet

Their publications are often featured in venues such as:

  • Nature Communications
  • The EMBO Journal
  • The Journal of Immunology
  • Oncogene
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation

    Patrick Viatour;Marie-Paule Merville;Vincent Bours;Alain Chariot

  • NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells

    Mohamed Bentires-Alj;Veronique Barbu;Marianne Fillet;Alain Chariot

  • Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

    Catherine Creppe;Lina Malinouskaya;Marie-Laure Volvert;Magali Gillard

  • TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

    L. Verstrepen;T. Bekaert;Tieu-Lan Chau;J. Tavernier

  • Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?

    Tieu-Lan Chau;Romain Gioia;Jean-Stéphane Gatot;Felicia Alina Patrascu

  • Transcription Impairment and Cell Migration Defects in Elongator-Depleted Cells: Implication for Familial Dysautonomia

    Pierre Close;Pierre Close;Nicola Hawkes;Isabelle Cornez;Catherine Creppe

  • NF- kappa B2/p100 induces Bcl-2 expression.

    P. Viatour;M. Bentires-Alj;A. Chariot;V. Deregowski

  • A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis

    Sophie Laguesse;Catherine Creppe;Danny D. Nedialkova;Pierre Paul Prévot

  • Codon-specific translation reprogramming promotes resistance to targeted therapy

    Francesca Rapino;Sylvain Delaunay;Florian Rambow;Zhaoli Zhou

  • The NF-κB-independent functions of IKK subunits in immunity and cancer

    Alain Chariot

  • Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.

    Fernanda Ortis;Pierre Pirot;Najib Naamane;A Y Kreins

  • EGFR and NF-κB: partners in cancer

    Kateryna Shostak;Alain Chariot

  • NF-κB, stem cells and breast cancer: the links get stronger

    Kateryna Shostak;Alain Chariot

  • CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.

    Antonio Leonardi;Alain Chariot;Estefania Claudio;Kirk Cunningham

  • Association of the Adaptor TANK with the IκB Kinase (IKK) Regulator NEMO Connects IKK Complexes with IKKε and TBK1 Kinases

    Alain Chariot;Antonio Leonardi;Jean-Noel Muller;Marianne Bonif

  • Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

    Vincent Quivy;Emmanuelle Adam;Yves Collette;Dominique Demonte

  • Molecular Mechanisms Involved in Schwann Cell Plasticity.

    Angélique Boerboom;Valérie Dion;Alain Chariot;Rachelle Franzen

  • The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.

    Estefania Claudio;Søren Ulrik Sønder;Sun Saret;Gabrielle Carvalho

  • GSK3-Mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity

    Patrick Viatour;Emmanuel Dejardin;Michael Warnier;Florence Lair

  • Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.

    Sylvain Delaunay;Francesca Rapino;Lars Tharun;Zhaoli Zhou

Frequent Co-Authors

Vincent Bours
Vincent Bours University of Liège
Laurent Nguyen
Laurent Nguyen University of Liège
Marie-Paule Merville
Marie-Paule Merville University of Liège
Jacques Piette
Jacques Piette University of Liège
Brigitte Malgrange
Brigitte Malgrange University of Liège
Ulrich Siebenlist
Ulrich Siebenlist National Institutes of Health
Carine Van Lint
Carine Van Lint Université Libre de Bruxelles
Arsène Burny
Arsène Burny Université Libre de Bruxelles
Reinhard Büttner
Reinhard Büttner University Hospital Cologne

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology opens doors to a variety of related fields and flexible learning opportunities. Many students interested in science also explore accelerated human services degree online programs, which offer a fast track to careers in support, advocacy, or community health roles.

If you’re considering a switch in career or field, it’s possible to leverage previous education experience. For example, educators often ask, can you become a speech pathologist with an education degree? With the right online coursework and credentials, such career transitions into allied health fields are increasingly accessible.

Science-minded students may also combine biology with fields like mathematics or design. Consider the flexibility of an online architecture programs or build a strong analytical foundation through a online mathematics degree. Each pathway offers unique interdisciplinary skills, expanding the range of opportunities for graduates.

Exploring these alternatives can help you customize your educational journey and find a career path that fits your interests and goals—whether you stick closely to biology or branch into new areas.

Best Scientists Citing Alain Chariot

Trending Scientists