Guy Haegeman

Overview

Best Publications

• Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

  Philippe Delerive;Karolien De Bosscher;Sandrine Besnard;Wim Vanden Berghe

  1348
  Citations

• The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

  Karolien De Bosscher;Wim Vanden Berghe;Guy Haegeman

  1163
  Citations

• Transcriptional activation of the NF‐κB p65 subunit by mitogen‐ and stress‐activated protein kinase‐1 (MSK1)

  Linda Vermeulen;Gert De Wilde;Petra Van Damme;Wim Vanden Berghe

  961
  Citations

• p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways Are Required for Nuclear Factor-κB p65 Transactivation Mediated by Tumor Necrosis Factor

  Wim Vanden Berghe;Stéphane Plaisance;Elke Boone;Karolien De Bosscher

  833
  Citations

• The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor.

  R. Beyaert;A. Cuenda;W. Vanden Berghe;S. Plaisance

  805
  Citations

• Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

  K Schulzeosthoff;Rudi Beyaert;Veronique Vandevoorde;Guy Haegeman

  698
  Citations

• Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

  Karolien De Bosscher;M. Lienhard Schmitz;Wim Vanden Berghe;Stéphane Plaisance

  461
  Citations

• The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

  Karen Heyninck;Dirk De Valck;Wim Vanden Berghe;Wim Van Criekinge

  434
  Citations

• The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter

  Wim Vanden Berghe;Karolien De Bosscher;Elke Boone;Stéphane Plaisance

  424
  Citations

• Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

  Karolien De Bosscher;Wim Vanden Berghe;Linda Vermeulen;Stéphane Plaisance

  412
  Citations

• Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit

  Linda Vermeulen;Gert De Wilde;Sofie Notebaert;Wim Vanden Berghe

  405
  Citations

• Interleukin-6, a mental cytokine.

  Anneleen Spooren;Krzysztof Kolmus;Guy Laureys;Ralph Clinckers

  404
  Citations

• Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

  Wim Vanden Berghe;Linda Vermeulen;Gert De Wilde;Karolien De Bosscher

  392
  Citations

• Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors

  Karolien De Bosscher;Wim Vanden Berghe;Guy Haegeman

  390
  Citations

• Minireview: latest perspectives on antiinflammatory actions of glucocorticoids.

  Karolien De Bosscher;Guy Haegeman

  376
  Citations

• Crosstalk in inflammation :The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

  Ilse M. E. Beck;Wim Vanden Berghe;Linda Vermeulen;Keith R. Yamamoto

  347
  Citations

• Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds

  Marjan Van Cleemput;Ko Cattoor;Karolien De Bosscher;Guy Haegeman

  343
  Citations

• Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

  Mary Kaileh;Wim Vanden Berghe;Arne Heyerick;Julie Horion

  342
  Citations

• Cross-talk between nuclear receptors and nuclear factor |[kappa]|B

  K De Bosscher;W Vanden Berghe;G Haegeman

  330
  Citations

• A fully dissociated compound of plant origin for inflammatory gene repression

  Karolien De Bosscher;Wim Vanden Berghe;Ilse M. E. Beck;Wim Van Molle

  328
  Citations