D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 13,408 118 World Ranking 5444 National Ranking 101

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Transcription factor, Molecular biology, Regulation of gene expression, Cell biology and Signal transduction. His Transcription factor research integrates issues from Activator, Psychological repression, Glucocorticoid receptor and Cancer research. His Molecular biology research includes themes of Lymphokine and Gene expression, Transactivation.

His biological study spans a wide range of topics, including Chromatin, NF-κB and Kinase. His Cell biology study combines topics in areas such as Cell culture, Apoptosis, Genetics, Plasmid and Proinflammatory cytokine. In the field of Signal transduction, his study on Cell signaling and G protein-coupled receptor overlaps with subjects such as 5-HT7 receptor.

His most cited work include:

  • The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression (757 citations)
  • Transcriptional activation of the NF‐κB p65 subunit by mitogen‐ and stress‐activated protein kinase‐1 (MSK1) (672 citations)
  • Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation (344 citations)

What are the main themes of his work throughout his whole career to date?

Guy Haegeman spends much of his time researching Cell biology, Molecular biology, Glucocorticoid receptor, Transcription factor and Signal transduction. In his research, CREB is intimately related to Proinflammatory cytokine, which falls under the overarching field of Cell biology. His Glucocorticoid receptor study integrates concerns from other disciplines, such as Transrepression and Transactivation.

Guy Haegeman focuses mostly in the field of Transactivation, narrowing it down to topics relating to NFKB1 and, in certain cases, Cancer research. His research investigates the connection between Transcription factor and topics such as Regulation of gene expression that intersect with issues in Chromatin and Histone. His study looks at the relationship between Signal transduction and fields such as Kinase, as well as how they intersect with chemical problems.

He most often published in these fields:

  • Cell biology (27.54%)
  • Molecular biology (25.15%)
  • Glucocorticoid receptor (25.75%)

What were the highlights of his more recent work (between 2010-2020)?

  • Glucocorticoid receptor (25.75%)
  • Transcription factor (24.55%)
  • Cell biology (27.54%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Glucocorticoid receptor, Transcription factor, Cell biology, Molecular biology and Signal transduction. His research in Glucocorticoid receptor intersects with topics in Transrepression and Transactivation. The various areas that he examines in his Transcription factor study include Regulation of gene expression and Gene expression.

His study in Cell biology is interdisciplinary in nature, drawing from both Proinflammatory cytokine and Nuclear receptor co-repressor 1. The concepts of his Molecular biology study are interwoven with issues in HEK 293 cells, Reporter gene and Luciferase. His research integrates issues of Viability assay, Kinase and Brain region in his study of Signal transduction.

Between 2010 and 2020, his most popular works were:

  • Interleukin-6, a mental cytokine. (243 citations)
  • Molecular insight in the multifunctional activities of Withaferin A (128 citations)
  • Role of the 5-HT7 receptor in the central nervous system: from current status to future perspectives. (113 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His main research concerns Transcription factor, Biochemistry, Glucocorticoid receptor, Gene expression and Internal medicine. His work carried out in the field of Transcription factor brings together such families of science as Signal transduction, Cell biology and Transcription. His research integrates issues of Transrepression, Transactivation, Cancer research and NFKB1 in his study of Glucocorticoid receptor.

His study in Transactivation is interdisciplinary in nature, drawing from both STAT6, Proinflammatory cytokine, IκBα and Glucocorticoid. His Gene expression research is multidisciplinary, incorporating elements of Molecular biology and Epigenetics. His Internal medicine research is multidisciplinary, relying on both Endocrinology and Osteoblast.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

Karolien De Bosscher;Wim Vanden Berghe;Guy Haegeman.
Endocrine Reviews (2003)

1074 Citations

Transcriptional activation of the NF‐κB p65 subunit by mitogen‐ and stress‐activated protein kinase‐1 (MSK1)

Linda Vermeulen;Gert De Wilde;Petra Van Damme;Wim Vanden Berghe.
The EMBO Journal (2003)

918 Citations

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

Karolien De Bosscher;M. Lienhard Schmitz;Wim Vanden Berghe;Stéphane Plaisance.
Proceedings of the National Academy of Sciences of the United States of America (1997)

438 Citations

The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

Karen Heyninck;Dirk De Valck;Wim Vanden Berghe;Wim Van Criekinge.
Journal of Cell Biology (1999)

412 Citations

The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter

Wim Vanden Berghe;Karolien De Bosscher;Elke Boone;Stéphane Plaisance.
Journal of Biological Chemistry (1999)

390 Citations

Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit

Linda Vermeulen;Gert De Wilde;Sofie Notebaert;Wim Vanden Berghe.
Biochemical Pharmacology (2002)

379 Citations

Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

Karolien De Bosscher;Wim Vanden Berghe;Linda Vermeulen;Stéphane Plaisance.
Proceedings of the National Academy of Sciences of the United States of America (2000)

378 Citations

Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors

Karolien De Bosscher;Wim Vanden Berghe;Guy Haegeman.
Journal of Neuroimmunology (2000)

370 Citations

Interleukin-6, a mental cytokine.

Anneleen Spooren;Krzysztof Kolmus;Guy Laureys;Ralph Clinckers.
Brain Research Reviews (2011)

368 Citations

Minireview: Latest Perspectives on Antiinflammatory Actions of Glucocorticoids

Karolien De Bosscher;Guy Haegeman.
Molecular Endocrinology (2009)

345 Citations

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