What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Transcription factor
His primary areas of investigation include Transcription factor, Glucocorticoid receptor, Regulation of gene expression, Cell biology and Transrepression.
Karolien De Bosscher combines subjects such as Cancer research, Psychological repression, Gene expression, Activator and Proinflammatory cytokine with his study of Transcription factor.
In his study, Receptor is inextricably linked to Inflammation, which falls within the broad field of Glucocorticoid receptor.
The various areas that Karolien De Bosscher examines in his Regulation of gene expression study include Molecular biology and Signal transduction.
His study on Kinase, Nucleus and Cytoplasm is often connected to R-SMAD as part of broader study in Cell biology.
His Transrepression study improves the overall literature in Transactivation.
His most cited work include:
- The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression (757 citations)
- The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter (319 citations)
- Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell (280 citations)
What are the main themes of his work throughout his whole career to date?
Karolien De Bosscher mainly focuses on Glucocorticoid receptor, Cell biology, Glucocorticoid, Transcription factor and Endocrinology.
His work carried out in the field of Glucocorticoid receptor brings together such families of science as Nuclear receptor, Transrepression, Transactivation and Pharmacology.
His studies deal with areas such as Peroxisome proliferator-activated receptor and Molecular biology as well as Nuclear receptor.
Karolien De Bosscher works mostly in the field of Cell biology, limiting it down to topics relating to Proinflammatory cytokine and, in certain cases, NFKB1 and Tumor necrosis factor alpha.
His Transcription factor research includes themes of Cancer research, Gene expression, Signal transduction, Activator and Regulation of gene expression.
His Endocrinology research integrates issues from Internal medicine, Mineralocorticoid receptor and Osteoblast.
He most often published in these fields:
- Glucocorticoid receptor (55.04%)
- Cell biology (21.71%)
- Glucocorticoid (20.93%)
What were the highlights of his more recent work (between 2016-2021)?
- Glucocorticoid receptor (55.04%)
- Glucocorticoid (20.93%)
- Immunology (17.83%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Glucocorticoid receptor, Glucocorticoid, Immunology, Inflammation and Receptor.
His Glucocorticoid receptor research incorporates elements of Tumor necrosis factor alpha, Nuclear receptor, Cancer research and Transactivation.
His biological study deals with issues like Gene expression, which deal with fields such as Proinflammatory cytokine, In vitro, Cortivazol and Peripheral blood mononuclear cell.
His Inflammation study deals with Necroptosis intersecting with Inflammatory bowel disease.
His research in Receptor intersects with topics in Cell biology, Endocrinology, Downregulation and upregulation and Transcription factor.
His studies link Transrepression with Cell biology.
Between 2016 and 2021, his most popular works were:
- Therapeutic Mechanisms of Glucocorticoids. (124 citations)
- Molecular Actions of PPARα in Lipid Metabolism and Inflammation. (94 citations)
- Glucocorticoid receptors: finding the middle ground (61 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Transcription factor
The scientist’s investigation covers issues in Immunology, Glucocorticoid receptor, Peroxisome proliferator-activated receptor, Inflammation and Innate immune system.
His work in the fields of Immunology, such as Sensitization, intersects with other areas such as House dust mite.
In his study, which falls under the umbrella issue of Glucocorticoid receptor, Transcription factor, CREB-binding protein and Hormone is strongly linked to Neuroscience.
Karolien De Bosscher interconnects Internal medicine and Endocrinology in the investigation of issues within Transcription factor.
His Peroxisome proliferator-activated receptor study combines topics in areas such as Nuclear receptor, Retinoid X receptor and Bioinformatics.
Karolien De Bosscher has researched Innate immune system in several fields, including Downregulation and upregulation and Signal transduction.
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