D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 63 Citations 22,292 103 World Ranking 1154 National Ranking 92

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Transcription factor

Cell biology, Signal transduction, SMAD, Transforming growth factor and Transcription factor are her primary areas of study. The various areas that Caroline S. Hill examines in her Cell biology study include Cell cycle and Transcription. Caroline S. Hill has researched Signal transduction in several fields, including TGF beta signaling pathway, ACVR2B, Cancer research and Gene expression.

Her studies deal with areas such as R-SMAD, Response element and MAPK/ERK pathway as well as SMAD. Her work deals with themes such as SUPERFAMILY, Receptor, Extracellular signal and Signalling, which intersect with Transforming growth factor. Her research in Transcription factor intersects with topics in Extracellular and Cell membrane.

Her most cited work include:

  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7 (1378 citations)
  • The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF (1179 citations)
  • Transcriptional Regulation by Extracellular Signals: Mechanisms and Specificity (1157 citations)

What are the main themes of her work throughout her whole career to date?

Caroline S. Hill mainly focuses on Cell biology, SMAD, Transforming growth factor, Signal transduction and Molecular biology. She has included themes like Receptor, Transcription factor and R-SMAD in her Cell biology study. The study incorporates disciplines such as Epithelial–mesenchymal transition, Xenopus and Peptide sequence in addition to SMAD.

Her Transforming growth factor research includes elements of SUPERFAMILY, Cell culture, Transcription and Signalling. Her Signal transduction study combines topics from a wide range of disciplines, such as Extracellular, Cancer research and Autocrine signalling. Her work deals with themes such as DNA, Regulation of gene expression, Bone morphogenetic protein and Mesoderm, which intersect with Molecular biology.

She most often published in these fields:

  • Cell biology (64.49%)
  • SMAD (33.64%)
  • Transforming growth factor (25.23%)

What were the highlights of her more recent work (between 2016-2021)?

  • Cell biology (64.49%)
  • Transforming growth factor (25.23%)
  • Phosphorylation (14.95%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Cell biology, Transforming growth factor, Phosphorylation, Receptor and SMAD. She studies Cell biology, focusing on Nodal signaling in particular. Her Transforming growth factor research incorporates elements of Carcinogenesis, Cancer research, Signal transduction and Downregulation and upregulation.

Her Signal transduction research includes elements of Extracellular, Signalling and In vivo. Her ACVR1, ACVR2A and Receptor clustering study in the realm of Receptor interacts with subjects such as Fibrodysplasia ossificans progressiva. Her SMAD study integrates concerns from other disciplines, such as Transcription, Kinase, Cell signaling and Gene isoform.

Between 2016 and 2021, her most popular works were:

  • TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition (81 citations)
  • Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling. (28 citations)
  • Spatial and temporal control of NODAL signaling. (25 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

The scientist’s investigation covers issues in Cell biology, Nodal signaling, NODAL, Transforming growth factor and Signal transduction. She works on Cell biology which deals in particular with Lefty. Her Lefty research is multidisciplinary, incorporating elements of Signalling and Cell fate determination.

Her Nodal signaling research includes themes of Chromatin, Transcription factor, Chromatin binding and Activin type 2 receptors. As a part of the same scientific family, Caroline S. Hill mostly works in the field of Epithelial–mesenchymal transition, focusing on Cell and, on occasion, SMAD. Her Morphogen study combines topics in areas such as Nodal Signaling Ligands, Endoderm, Mesoderm and Fibroblast growth factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

Caroline S. Hill;Judy Wynne;Richard Treisman.
Cell (1995)

1928 Citations

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.

Gareth J. Inman;Francisco J. Nicolás;James F. Callahan;John D. Harling.
Molecular Pharmacology (2002)

1810 Citations

Transcriptional Regulation by Extracellular Signals: Mechanisms and Specificity

Caroline S Hill;Richard Treisman.
Cell (1995)

1719 Citations

New insights into TGF-beta-Smad signalling.

Peter ten Dijke;Caroline S Hill.
Trends in Biochemical Sciences (2004)

1600 Citations

TGFβ–SMAD signal transduction: molecular specificity and functional flexibility

Bernhard Schmierer;Caroline S. Hill.
Nature Reviews Molecular Cell Biology (2007)

1425 Citations

TGF-β Superfamily Signaling in Embryonic Development and Homeostasis

Mary Y. Wu;Caroline S. Hill.
Developmental Cell (2009)

842 Citations

Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility.

Silvia Giampieri;Cerys Manning;Steven Hooper;Louise Jones.
Nature Cell Biology (2009)

723 Citations

Alterations in components of the TGF-β superfamily signaling pathways in human cancer

Laurence Levy;Caroline S. Hill.
Cytokine & Growth Factor Reviews (2006)

689 Citations

Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity

Gareth J. Inman;Francisco J. Nicolás;Caroline S. Hill.
Molecular Cell (2002)

554 Citations

Structure of the HMG box motif in the B-domain of HMG1.

H.M. Weir;P.J. Kraulis;C.S. Hill;A.R.C. Raine.
The EMBO Journal (1994)

518 Citations

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