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D-Index & Metrics

Chemistry

D-Index
57
Citations
15869
World Ranking
10938
National Ranking
619

Biology and Biochemistry

D-Index
65
Citations
20025
World Ranking
9009
National Ranking
688

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ernest D. Laue is affiliated with the University of Cambridge in the United Kingdom and conducts research primarily in the fields of biochemistry, genetics, and molecular biology. Their research focuses on molecular biology, biophysics, genetics, pediatrics, perinatology, child health, and plant science.

Their main research topics include:

  • Genomics and Chromatin Dynamics
  • Advanced Fluorescence Microscopy Techniques
  • Genetic Syndromes and Imprinting
  • Epigenetics and DNA Methylation
  • Prenatal Screening and Diagnostics
  • Advanced biosensing and bioanalysis techniques
  • Pluripotent Stem Cells Research

Ernest D. Laue has authored several papers of note, including:

  • "Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3," published in 2021 in Nature Communications
  • "Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD," published in 2023 in Nature Structural & Molecular Biology
  • "Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency," published in 2024 in Molecular Cell
  • "Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics," published in 2020 in bioRxiv (Cold Spring Harbor Laboratory)
  • "Unorthodox PCNA Binding by Chromatin Assembly Factor 1," published in 2022 in International Journal of Molecular Sciences

Frequent coauthors include:

  • Xiaoyan Ma
  • Nicola Reynolds
  • Brian Hendrich
  • Wayne Boucher
  • David Lando

Regular publication venues for Ernest D. Laue include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Structural & Molecular Biology
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • Molecular Cell

Ernest D. Laue is recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • The CCPN data model for NMR spectroscopy: Development of a software pipeline

    Wim F. Vranken;Wayne Boucher;Tim J. Stevens;Rasmus H. Fogh

  • Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

    Takashi Nagano;Yaniv Lubling;Tim J. Stevens;Stefan Schoenfelder

  • 3D structures of individual mammalian genomes studied by single-cell Hi-C

    Tim J. Stevens;Tim J. Stevens;David Lando;Srinjan Basu;Liam P. Atkinson

  • Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9.

    Peter R. Nielsen;Daniel Nietlispach;Helen R. Mott;Juliana Callaghan

  • Experiments for recording pure-absorption heteronuclear correlation spectra using pulsed field gradients

    Adrian L Davis;James Keeler;Ernest D Laue;Detlef Moskau

  • Structure of the HMG box motif in the B-domain of HMG1.

    H.M. Weir;P.J. Kraulis;C.S. Hill;A.R.C. Raine

  • Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins.

    Natalia Murzina;Alain Verreault;Ernest Laue;Bruce Stillman

  • The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer

    Sally V. Brasher;Brian O. Smith;Rasmus H. Fogh;Daniel Nietlispach

  • Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

    Katrin Rittinger;Philip A. Walker;John F. Eccleston;Kurshid Nurmahomed

  • Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

    P.J Kraulis;P.J Domaille;S.L Campbell-Burk;T Van Aken

  • Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin.

    Abarna Thiru;Daniel Nietlispach;Helen R Mott;Mitsuru Okuwaki

  • Exponential sampling, an alternative method for sampling in two-dimensional NMR experiments

    J.C.J Barna;E.D Laue;M.R Mayger;J Skilling

  • The SCF/Slimb Ubiquitin Ligase Limits Centrosome Amplification through Degradation of SAK/PLK4

    Inês Cunha-Ferreira;Inês Cunha-Ferreira;Ana Rodrigues-Martins;Ana Rodrigues-Martins;Inês Bento;Maria Riparbelli

  • Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.

    Deborah H. Brotherton;Venugopal Dhanaraj;Scott Wick;Leonardo Brizuela

  • Structure of Cdc42 bound to the GTPase binding domain of PAK.

    Angela Morreale;Meenakshi Venkatesan;Helen R. Mott;Darerca Owen

  • Maximum entropy signal processing in practical NMR spectroscopy

    Sibusiso Sibisi;John Skilling;Richard G. Brereton;Ernest D. Laue

  • The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.

    Stephen H. McLaughlin;Frank Sobott;Zhong-ping Yao;Wei Zhang

  • Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

    Natalia V. Murzina;Xue-Yuan Pei;Wei Zhang;Mike Sparkes

  • Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

    Helen R. Mott;Darerca Owen;Daniel Nietlispach;Peter N. Lowe

  • Structure of the chromatin binding (chromo) domain from mouse modifier protein 1

    L. J. Ball;N. V. Murzina;R. W. Broadhurst;A. R. C. Raine

Frequent Co-Authors

James Staunton
James Staunton University of Cambridge
David Klenerman
David Klenerman University of Cambridge
David M. Glover
David M. Glover California Institute of Technology
Richard N. Perham
Richard N. Perham University of Cambridge
Ashwin A. Seshia
Ashwin A. Seshia University of Cambridge
Adrian L. V. Davis
Adrian L. V. Davis University of Pretoria
Wim F. Vranken
Wim F. Vranken Vrije Universiteit Brussel
Carol V. Robinson
Carol V. Robinson University of Oxford
Imre Berger
Imre Berger University of Bristol
Kathryn S. Lilley
Kathryn S. Lilley University of Cambridge

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