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Biology and Biochemistry

D-Index
74
Citations
18598
World Ranking
5626
National Ranking
435

Overview

Paul A. Bates is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily spans the broad field of Biochemistry, Genetics, and Molecular Biology, with a focus on several subfields including Molecular Biology, Cancer Research, Cell Biology, Pulmonary and Respiratory Medicine, and Materials Chemistry.

The scientist's work addresses multiple topics, notably Cancer Genomics and Diagnostics, Protein Structure and Dynamics, Renal cell carcinoma treatment, Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, Computational Drug Discovery Methods, and Genomics and Phylogenetic Studies.

Recent publications demonstrate a diverse research output across various respected academic journals and venues. Select papers authored or coauthored by Paul A. Bates include:

  • Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing, 2020, Immunity
  • A FIJI macro for quantifying pattern in extracellular matrix, 2021, Life Science Alliance
  • Prediction of protein assemblies, the next frontier: The CASP14-CAPRI experiment, 2021, Proteins Structure Function and Bioinformatics
  • Selection of metastasis competent subclones in the tumour interior, 2021, Nature Ecology & Evolution
  • Impact of AlphaFold on structure prediction of protein complexes: The CASP15-CAPRI experiment, 2023, Proteins Structure Function and Bioinformatics

The scientist frequently collaborates with other researchers in the field. Their frequent coauthors include Xiao Fu, Erik Sahai, Charles Swanton, Raphaël A. G. Chaleil, and Tereza Clarence, reflecting a network of collaborative work across multiple disciplines.

Publication venues where Paul A. Bates has contributed multiple times include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Proteins Structure Function and Bioinformatics
  • Nature Ecology & Evolution
  • Immunity

Best Publications

  • Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

    Marco Gerlinger;Stuart Horswell;James Larkin;Andrew J Rowan

  • Enhancement of protein modeling by human intervention in applying the automatic programs 3D-JIGSAW and 3D-PSSM.

    Paul A. Bates;Lawrence A. Kelley;Robert M. MacCallum;Michael J.E. Sternberg

  • Global topological features of cancer proteins in the human interactome

    Pall F. Jonsson;Paul A. Bates

  • Structure of the AAA ATPase p97.

    Xiaodong Zhang;Anthony Shaw;Paul A. Bates;Richard H. Newman

  • Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.

    Thom Vreven;Iain H. Moal;Anna Vangone;Brian G. Pierce

  • Reversal of DNA alkylation damage by two human dioxygenases

    Tod Duncan;Sarah C. Trewick;Pertti Koivisto;Paul A. Bates

  • Repair of alkylated DNA: recent advances.

    Barbara Sedgwick;Paul A Bates;Johanna Paik;Susan C Jacobs

  • Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

    Melda Tozluoğlu;Alexander L. Tournier;Robert P. Jenkins;Steven Hooper

  • The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site.

    Anthony R. Berendt;Alison McDowall;Alister G. Craig;Paul A. Bates

  • Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.

    Xiaodong Zhang;Solange Moréra;Solange Moréra;Paul A. Bates;Philip C. Whitehead

  • A structure-based benchmark for protein–protein binding affinity

    Panagiotis L. Kastritis;Iain H. Moal;Howook Hwang;Zhiping Weng

  • SwarmDock: a server for flexible protein-protein docking

    Mieczyslaw Torchala;Iain H. Moal;Raphael A. G. Chaleil;Juan Fernandez-Recio

  • Agent-based simulation of Notch mediated tip cell selection in angiogenic sprout initialisation

    Katie Bentley;Holger Gerhardt;Paul A. Bates

  • An automated classification of the structure of protein loops

    Baldomero Oliva;Paul A. Bates;Enrique Querol;Francesc X. Avilés

  • Planar polarization of the atypical myosin Dachs orients cell divisions in Drosophila

    Yanlan Mao;Alexander L. Tournier;Paul A. Bates;Jonathan E. Gale

  • OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.

    Grant C Sellar;Karen P Watt;Genevieve J Rabiasz;Euan A Stronach

  • Recognition of analogous and homologous protein folds: analysis of sequence and structure conservation.

    Robert B Russell;Mansoor A.S Saqi;Roger A Sayle;Paul A Bates

  • Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

    Bernhard Schmierer;Alexander L. Tournier;Paul A. Bates;Caroline S. Hill

  • Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis

    Pall F Jonsson;Tamara Cavanna;Daniel Zicha;Paul A Bates

  • Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.

    Katie Bentley;Giovanni Mariggi;Holger Gerhardt;Paul A. Bates

Frequent Co-Authors

Michael B. Hursthouse
Michael B. Hursthouse University of Southampton
Michael J.E. Sternberg
Michael J.E. Sternberg Imperial College London
Juan Fernández-Recio
Juan Fernández-Recio Spanish National Research Council
Paul S. Freemont
Paul S. Freemont Imperial College London
Erik Sahai
Erik Sahai The Francis Crick Institute
Charles Swanton
Charles Swanton The Francis Crick Institute
Zhiping Weng
Zhiping Weng University of Massachusetts Chan Medical School
Thom Vreven
Thom Vreven Visterra (United States)
Nancy Hogg
Nancy Hogg Cancer Research UK London Research Institute
James Larkin
James Larkin Royal Marsden NHS Foundation Trust

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