Member of the European Molecular Biology Organization (EMBO)
Fellow of The Academy of Medical Sciences, United Kingdom
The scientist’s investigation covers issues in Cell biology, Motility, Cancer cell, Cancer research and Kinase. His research brings together the fields of Cell cycle and Cell biology. In his research, Chemotaxis is intimately related to Metastasis, which falls under the overarching field of Motility.
His Cancer cell research incorporates elements of Acquired immune system, Collective cell migration, Collective migration and Neoplasm Invasiveness. His Cancer research study combines topics from a wide range of disciplines, such as Chemokine, XCL1 and Cancer immunotherapy. His biological study spans a wide range of topics, including Amoeboid movement, Guanine nucleotide exchange factor, Dock3 and Actin.
His scientific interests lie mostly in Cell biology, Cancer research, Cancer cell, Metastasis and Motility. His Cell biology study combines topics in areas such as Cell, Cytoskeleton and Cell culture. His work deals with themes such as Epidermal growth factor and In vivo, which intersect with Cancer research.
Erik Sahai has included themes like Cell cycle, Cell signaling, Neuroscience and Oncolytic virus in his Cancer cell study. He has researched Metastasis in several fields, including Breast cancer and Pathology. His study focuses on the intersection of Motility and fields such as Cell adhesion with connections in the field of Cell adhesion molecule.
Erik Sahai focuses on Cancer research, Cancer cell, Cell biology, Metastasis and Tumor microenvironment. When carried out as part of a general Cancer research research project, his work on Stromal cell is frequently linked to work in Population, therefore connecting diverse disciplines of study. His research integrates issues of Cell, Melanoma, Oncolytic virus and Crosstalk in his study of Cancer cell.
His studies in Cell biology integrate themes in fields like Cyclin-dependent kinase 1 and Dendritic cell. His work on Cancer dormancy is typically connected to Selection as part of general Metastasis study, connecting several disciplines of science. Erik Sahai works mostly in the field of Tumor microenvironment, limiting it down to concerns involving Cell type and, occasionally, Lymphocyte, Immunotherapy, Neuroscience and Treatment outcome.
His primary scientific interests are in Cell biology, Cancer research, Cancer cell, Bone marrow and Cancer-Associated Fibroblasts. His Cell biology research incorporates elements of Cancer and Oncolytic virus. His work on Stromal cell as part of general Cancer research study is frequently linked to Population, therefore connecting diverse disciplines of science.
His biological study spans a wide range of topics, including Transcytosis and IRF3. The various areas that he examines in his Bone marrow study include Cyclin-dependent kinase 1, Dendritic cell and Progenitor cell, Fate mapping. Cell culture is closely connected to Disease progression in his research, which is encompassed under the umbrella topic of Cancer-Associated Fibroblasts.
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RHO-GTPases and cancer.
Erik Sahai;Christopher J. Marshall.
Nature Reviews Cancer (2002)
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.
Cedric Gaggioli;Steven Hooper;Cristina Hidalgo-Carcedo;Robert Grosse.
Nature Cell Biology (2007)
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
Mathew L. Coleman;Erik A. Sahai;Margaret Yeo;Marta Bosch.
Nature Cell Biology (2001)
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
Erik Sahai;Christopher J Marshall.
Nature Cell Biology (2003)
A framework for advancing our understanding of cancer-associated fibroblasts
Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo.
Nature Reviews Cancer (2020)
Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement
Victoria Sanz-Moreno;Gilles Gadea;Jessica Ahn;Hugh Paterson.
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo;Nil Ege;Araceli Grande-Garcia;Steven Hooper.
Nature Cell Biology (2013)
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Jan P. Böttcher;Eduardo Bonavita;Probir Chakravarty;Hanna Blees.
Classifying collective cancer cell invasion
Peter Friedl;Joseph Locker;Erik Sahai;Jeffrey E. Segall.
Nature Cell Biology (2012)
Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop
Sumanta Goswami;Erik Sahai;Erik Sahai;Jeffrey B. Wyckoff;Michael Cammer.
Cancer Research (2005)
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