D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 31,518 156 World Ranking 3623 National Ranking 259

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Cancer
  • Genetics
  • Apoptosis

The scientist’s investigation covers issues in Cell biology, Motility, Cancer cell, Cancer research and Kinase. His research brings together the fields of Cell cycle and Cell biology. In his research, Chemotaxis is intimately related to Metastasis, which falls under the overarching field of Motility.

His Cancer cell research incorporates elements of Acquired immune system, Collective cell migration, Collective migration and Neoplasm Invasiveness. His Cancer research study combines topics from a wide range of disciplines, such as Chemokine, XCL1 and Cancer immunotherapy. His biological study spans a wide range of topics, including Amoeboid movement, Guanine nucleotide exchange factor, Dock3 and Actin.

His most cited work include:

  • RHO-GTPases and cancer. (1216 citations)
  • Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. (1012 citations)
  • Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I (992 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Cancer research, Cancer cell, Metastasis and Motility. His Cell biology study combines topics in areas such as Cell, Cytoskeleton and Cell culture. His work deals with themes such as Epidermal growth factor and In vivo, which intersect with Cancer research.

Erik Sahai has included themes like Cell cycle, Cell signaling, Neuroscience and Oncolytic virus in his Cancer cell study. He has researched Metastasis in several fields, including Breast cancer and Pathology. His study focuses on the intersection of Motility and fields such as Cell adhesion with connections in the field of Cell adhesion molecule.

He most often published in these fields:

  • Cell biology (55.00%)
  • Cancer research (37.50%)
  • Cancer cell (23.75%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (37.50%)
  • Cancer cell (23.75%)
  • Cell biology (55.00%)

In recent papers he was focusing on the following fields of study:

Erik Sahai focuses on Cancer research, Cancer cell, Cell biology, Metastasis and Tumor microenvironment. When carried out as part of a general Cancer research research project, his work on Stromal cell is frequently linked to work in Population, therefore connecting diverse disciplines of study. His research integrates issues of Cell, Melanoma, Oncolytic virus and Crosstalk in his study of Cancer cell.

His studies in Cell biology integrate themes in fields like Cyclin-dependent kinase 1 and Dendritic cell. His work on Cancer dormancy is typically connected to Selection as part of general Metastasis study, connecting several disciplines of science. Erik Sahai works mostly in the field of Tumor microenvironment, limiting it down to concerns involving Cell type and, occasionally, Lymphocyte, Immunotherapy, Neuroscience and Treatment outcome.

Between 2018 and 2021, his most popular works were:

  • A framework for advancing our understanding of cancer-associated fibroblasts (332 citations)
  • Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress. (41 citations)
  • Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions. (33 citations)

In his most recent research, the most cited papers focused on:

  • Cancer
  • Genetics
  • Apoptosis

His primary scientific interests are in Cell biology, Cancer research, Cancer cell, Bone marrow and Cancer-Associated Fibroblasts. His Cell biology research incorporates elements of Cancer and Oncolytic virus. His work on Stromal cell as part of general Cancer research study is frequently linked to Population, therefore connecting diverse disciplines of science.

His biological study spans a wide range of topics, including Transcytosis and IRF3. The various areas that he examines in his Bone marrow study include Cyclin-dependent kinase 1, Dendritic cell and Progenitor cell, Fate mapping. Cell culture is closely connected to Disease progression in his research, which is encompassed under the umbrella topic of Cancer-Associated Fibroblasts.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

RHO-GTPases and cancer.

Erik Sahai;Christopher J. Marshall.
Nature Reviews Cancer (2002)

1900 Citations

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.

Cedric Gaggioli;Steven Hooper;Cristina Hidalgo-Carcedo;Robert Grosse.
Nature Cell Biology (2007)

1496 Citations

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

Mathew L. Coleman;Erik A. Sahai;Margaret Yeo;Marta Bosch.
Nature Cell Biology (2001)

1446 Citations

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Erik Sahai;Christopher J Marshall.
Nature Cell Biology (2003)

1362 Citations

A framework for advancing our understanding of cancer-associated fibroblasts

Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo.
Nature Reviews Cancer (2020)

1177 Citations

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

Victoria Sanz-Moreno;Gilles Gadea;Jessica Ahn;Hugh Paterson.
Cell (2008)

1044 Citations

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

Fernando Calvo;Nil Ege;Araceli Grande-Garcia;Steven Hooper.
Nature Cell Biology (2013)

1041 Citations

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

Jan P. Böttcher;Eduardo Bonavita;Probir Chakravarty;Hanna Blees.
Cell (2018)

897 Citations

Classifying collective cancer cell invasion

Peter Friedl;Joseph Locker;Erik Sahai;Jeffrey E. Segall.
Nature Cell Biology (2012)

836 Citations

Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop

Sumanta Goswami;Erik Sahai;Erik Sahai;Jeffrey B. Wyckoff;Michael Cammer.
Cancer Research (2005)

787 Citations

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