World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
22645
World Ranking
7662
National Ranking
3492

Overview

Patricia J. Keely is affiliated with the University of Wisconsin-Madison in the United States. Their research mainly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Cancer Research, Immunology and Allergy, and Oncology. They have also contributed to studies involving Artificial Intelligence and Pulmonary and Respiratory Medicine.

Their work covers a range of topics including Cell Adhesion Molecules Research, Breast Cancer Treatment Studies, Cancer Cells and Metastasis, AI in cancer detection, Digital Radiography and Breast Imaging, Cellular Mechanics and Interactions, and Protease and Inhibitor Mechanisms.

Patricia J. Keely has published extensively in several venues. The most frequent publication outlet is UNC Libraries, where they have 5 publications. Other publication venues include the Journal of Clinical Investigation and Breast Cancer Research, each with one publication, as well as Preprints.org.

Recent notable papers from Keely include:

  • Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217, 2020, Journal of Clinical Investigation
  • Mammary collagen architecture and its association with mammographic density and lesion severity among women undergoing image-guided breast biopsy, 2021, Breast Cancer Research
  • ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix, 2020, UNC Libraries
  • The α 2 β 1 Integrin Is a Necessary Co-receptor for Collagen-induced Activation of Syk and the Subsequent Phosphorylation of Phospholipase Cγ2 in Platelets, 2021, UNC Libraries
  • R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells, 2021, UNC Libraries

Throughout their research career, Keely has collaborated frequently with several co-authors, including Suzanne M. Ponik, John Shepherd, Kevin W. Eliceiri, Channing J. Der, and Leslie V. Parise. Each of these collaborators has partnered with Keely in multiple publications.

Best Publications

  • Collagen reorganization at the tumor-stromal interface facilitates local invasion

    Paolo P Provenzano;Kevin W Eliceiri;Jay M Campbell;David R Inman

  • Collagen density promotes mammary tumor initiation and progression

    Paolo P Provenzano;David R Inman;Kevin W Eliceiri;Justin G Knittel

  • Focal adhesion regulation of cell behavior

    Michele A Wozniak;Katarzyna Modzelewska;Lina Kwong;Patricia J Keely

  • Aligned collagen is a prognostic signature for survival in human breast carcinoma.

    Matthew W. Conklin;Jens C. Eickhoff;Kristin M. Riching;Carolyn A. Pehlke

  • Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

    Patricia J. Keely;John K. Westwick;Ian P. Whitehead;Channing J. Der

  • Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

    Jacky G. Goetz;Susana Minguet;Inmaculada Navarro-Lérida;Juan José Lazcano

  • ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

    Michele A. Wozniak;Radhika Desai;Patricia A. Solski;Channing J. Der

  • Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

    Paolo P Provenzano;David R Inman;Kevin W Eliceiri;Patricia J Keely

  • Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.

    Paolo P. Provenzano;Patricia J. Keely

  • Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

    Paolo P. Provenzano;David R. Inman;Kevin W. Eliceiri;Steven M. Trier

  • Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression

    Pepper Schedin;Patricia J. Keely

  • 3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

    Kristin M. Riching;Benjamin L. Cox;Max R. Salick;Carolyn Pehlke

  • Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer.

    Jeremy S. Bredfeldt;Yuming Liu;Carolyn A. Pehlke;Matthew W. Conklin

  • Metabolic Mapping of MCF10A Human Breast Cells via Multiphoton Fluorescence Lifetime Imaging of the Coenzyme NADH

    Damian K. Bird;Long Yan;Kristin M. Vrotsos;Kevin W. Eliceiri

  • In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia

    Melissa C. Skala;Kristin M. Riching;Damian K. Bird;Annette Gendron-Fitzpatrick

  • The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

    Kun Zhang;Callie A. Corsa;Suzanne M. Ponik;Julie L. Prior

  • Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

    Traci R. Lyons;Jenean O'Brien;Virginia F. Borges;Virginia F. Borges;Matthew W. Conklin

  • Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells

    Patricia J. Keely;Alan M. Fong;Mary M. Zutter;Samuel A. Santoro

  • Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments.

    Georg Fluegen;Georg Fluegen;Alvaro Avivar-Valderas;Yarong Wang;Michael R. Padgen

  • Why the stroma matters in breast cancer: Insights into breast cancer patient outcomes through the examination of stromal biomarkers

    Matthew W. Conklin;Patricia J. Keely

Frequent Co-Authors

John S. Condeelis
John S. Condeelis Albert Einstein College of Medicine
Julio A. Aguirre-Ghiso
Julio A. Aguirre-Ghiso Icahn School of Medicine at Mount Sinai
Pepper Schedin
Pepper Schedin Oregon Health & Science University
Virginia F. Borges
Virginia F. Borges University of Colorado Boulder
Valerie M. Weaver
Valerie M. Weaver University of California, San Francisco
Gregory D. Longmore
Gregory D. Longmore Washington University in St. Louis
Vladislav V. Verkhusha
Vladislav V. Verkhusha Albert Einstein College of Medicine
David J. Beebe
David J. Beebe University of Wisconsin–Madison
Alissa M. Weaver
Alissa M. Weaver Vanderbilt University
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Patricia J. Keely

Trending Scientists