World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
15872
World Ranking
7444
National Ranking
3394

Overview

Gregory D. Longmore is affiliated with Washington University in St. Louis in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a strong emphasis on cancer biology and cellular mechanisms.

Their work is distributed across various publication venues, with a notable number of articles appearing in

  • Cancer Research (9 publications)
  • Gynecologic Oncology (7 publications)
  • Molecular Cancer Research (3 publications)
  • Nature Reviews Molecular Cell Biology (2 publications)
  • Communications Biology (2 publications)

Longmore's main fields of study include biochemistry, genetics and molecular biology (44 publications), and medicine (43 publications). Subfields include molecular biology, oncology, cell biology, immunology and allergy, and cancer research. Their research addresses a variety of topics, especially:

  • Cancer Cells and Metastasis
  • Cell Adhesion Molecules Research
  • Cellular Mechanics and Interactions
  • Wnt/β-catenin signaling in development and cancer
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Research and Treatments
  • Ovarian cancer diagnosis and treatment

Frequent co-authors of Longmore include:

  • Katherine C. Fuh
  • Whitney R. Grither
  • Vasilios A. Morikis
  • Premal H. Thaker
  • David G. Mutch

Among the recent papers featuring Longmore's contributions are:

  • "Guidelines and definitions for research on epithelial-mesenchymal transition" (2020), published in Nature Reviews Molecular Cell Biology
  • "Senescent CAFs Mediate Immunosuppression and Drive Breast Cancer Progression" (2024), published in Cancer Discovery
  • "DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression" (2023), published in Oncogene
  • "Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity" (2021), published in Cell Reports
  • "Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival" (2023), published in Communications Biology

This body of work reflects investigations on cellular and molecular mechanisms underlying cancer progression, especially focusing on cancer-associated fibroblasts, epithelial-mesenchymal transition, tumor microenvironment, and ovarian and breast cancer pathology.

Best Publications

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • A distinctive role for focal adhesion proteins in three-dimensional cell motility

    Stephanie I. Fraley;Yunfeng Feng;Yunfeng Feng;Ranjini Krishnamurthy;Dong Hwee Kim

  • Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

    Megan K. Ruhland;Andrew J. Loza;Aude Helene Capietto;Xianmin Luo

  • Structure, function, and activation of the erythropoietin receptor.

    Hagop Youssoufian;Gregory Longmore;Drorit Neumann;Akihiko Yoshimura

  • Homodimerization and constitutive activation of the erythropoietin receptor.

    Stephanie S. Watowich;Akihiko Yoshimura;Gregory D. Longmore;Gregory D. Longmore;Douglas J. Hilton

  • The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

    Kun Zhang;Callie A. Corsa;Suzanne M. Ponik;Julie L. Prior

  • Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

    Akihiko Yoshimura;Gregory Longmore;Gregory Longmore;Harvey F. Lodish

  • The conserved box 1 motif of cytokine receptors is required for association with JAK kinases.

    J.William Tanner;Wen Chen;Robert L. Young;Gregory D. Longmore

  • Upholding a role for EMT in breast cancer metastasis

    Xin Ye;Thomas Brabletz;Yibin Kang;Gregory D. Longmore

  • A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.

    Brandon K. Hadland;Stacey S. Huppert;Jyotshnabala Kanungo;Yingzi Xue

  • Ajuba LIM proteins are negative regulators of the Hippo signaling pathway.

    Meghna Das Thakur;Yunfeng Feng;Radhika Jagannathan;Midori J. Seppa

  • Product-identification and substrate-specificity studies of the GDP-l-fucose: 2-acetamido-2-deoxy-β-d-glucoside (fuc→asn-linked GlcNAc) 6-α-l-fucosyltransferase in a golgi-rich fraction from porcine liver☆

    Gregory D. Longmore;Harry Schachter

  • The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression

    Zhaoyuan Hou;Hongzhuang Peng;Kasirajan Ayyanathan;Kai Ping Yan

  • γ-Secretase inhibitors repress thymocyte development

    Brandon K. Hadland;Nancy R. Manley;Dong Ming Su;Gregory D. Longmore

  • Transient SNAIL1 Expression Is Necessary for Metastatic Competence in Breast Cancer

    Hung D Tran;Krishna Luitel;Michael Kim;Kaihua Zhang

  • Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions.

    Stephanie I. Fraley;Pei Hsun Wu;Lijuan He;Yunfeng Feng

  • Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

    Dong Hwee Kim;Shyam B. Khatau;Yunfeng Feng;Yunfeng Feng;Sam Walcott;Sam Walcott

  • The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

    Allison B. Chambliss;Shyam B. Khatau;Nicholas Erdenberger;D. Kyle Robinson

  • Temporal and Spatial cooperation of Snail1 and Twist1 during Epithelial-Mesenchymal Transition predicts for human breast cancer recurrence

    David D. Tran;Callie Ann S. Corsa;Hirak Biswas;Rebecca L. Aft

  • An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: a cytokine receptor superfamily oncogene.

    Gregory D. Longmore;Gregory D. Longmore;Harvey F. Lodish

Frequent Co-Authors

Denis Wirtz
Denis Wirtz Johns Hopkins University
Stephanie S. Watowich
Stephanie S. Watowich The University of Texas MD Anderson Cancer Center
Mark A. Goldsmith
Mark A. Goldsmith Revolution Medicines
Frank J. Rauscher
Frank J. Rauscher The Wistar Institute
Douglas J. Hilton
Douglas J. Hilton Walter and Eliza Hall Institute of Medical Research
Patricia J. Keely
Patricia J. Keely University of Wisconsin–Madison
Roberta Faccio
Roberta Faccio Washington University in St. Louis
Kathleen D. Liu
Kathleen D. Liu University of California, San Francisco

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