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D-Index & Metrics

Molecular Biology

D-Index
51
Citations
20655
World Ranking
2461
National Ranking
1211

Overview

Edna Cukierman is affiliated with Fox Chase Cancer Center in the United States and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology, with a particular focus on oncology.

The main fields of study for Cukierman include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these areas, their subfields of study comprise:

  • Oncology
  • Molecular Biology
  • Cell Biology
  • Cancer Research
  • Genetics

The research has centered on topics such as:

  • Pancreatic and Hepatic Oncology Research
  • Cancer Cells and Metastasis
  • Cellular Mechanics and Interactions
  • Ferroptosis and cancer prognosis
  • Epigenetics and DNA Methylation
  • Caveolin-1 and cellular processes
  • Pancreatic function and diabetes

Edna Cukierman has published numerous papers, including the following recent works:

  • "A framework for advancing our understanding of cancer-associated fibroblasts," 2020, Nature Reviews. Cancer
  • "Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer," 2020, Cancer Cell
  • "Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours," 2020, Nature Metabolism
  • "Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression," 2020, Cancer Discovery
  • "Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma," 2022, Nature Communications

Frequent co-authors collaborating with Cukierman include:

  • Janusz Franco-Barraza
  • Ralph Francescone
  • Débora B. Vendramini-Costa
  • Igor Astsaturov
  • Tiffany Luong

Research papers by Cukierman have been published in various venues, with multiple contributions to:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Cell
  • Cancer Discovery
  • Nature Communications

Best Publications

  • Taking Cell-Matrix Adhesions to the Third Dimension

    Edna Cukierman;Roumen Pankov;Daron R. Stevens;Kenneth M. Yamada

  • A framework for advancing our understanding of cancer-associated fibroblasts

    Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo

  • Modeling Tissue Morphogenesis and Cancer in 3D

    Kenneth M. Yamada;Edna Cukierman

  • Cell interactions with three-dimensional matrices.

    Edna Cukierman;Roumen Pankov;Kenneth M Yamada

  • Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

    Jacky G. Goetz;Susana Minguet;Inmaculada Navarro-Lérida;Juan José Lazcano

  • Integrin Dynamics and Matrix Assembly: Tensin-Dependent Translocation of α5β1 Integrins Promotes Early Fibronectin Fibrillogenesis

    Roumen Pankov;Edna Cukierman;Ben-Zion Katz;Kazue Matsumoto

  • A Rac switch regulates random versus directionally persistent cell migration.

    Roumen Pankov;Yukinori Endo;Sharona Even-Ram;Masaru Araki

  • The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization

    Unknown

  • FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

    Unknown

  • Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

    Amanpreet Kaur;Amanpreet Kaur;Amanpreet Kaur;Brett L. Ecker;Stephen M. Douglass;Curtis H. Kugel

  • Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer

    Unknown

  • Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.

    Michael D. Amatangelo;Daniel E. Bassi;Andrés J.P. Klein-Szanto;Edna Cukierman

  • Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression.

    Unknown

  • Dimensions and dynamics in integrin function

    K.M. Yamada;R. Pankov;E. Cukierman;E. Cukierman

  • The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation

    Takaomi Okawa;Carmen Z. Michaylira;Jiri Kalabis;Douglas B. Stairs

  • Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts

    Unknown

  • The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for ARF1.

    Tomohiko Aoe;Edna Cukierman;Agnes Lee;Dan Cassel

  • uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Lars H. Engelholm;Karin List;Karin List;Sarah Netzel-Arnett;Edna Cukierman

  • Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells

    Ilya Serebriiskii;Remedios Castelló-Cros;Acacia Lamb;Erica A. Golemis

  • Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions.

    Unknown

Frequent Co-Authors

Kenneth M. Yamada
Kenneth M. Yamada National Institutes of Health
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Bruce J. Baum
Bruce J. Baum National Institutes of Health
Erica A. Golemis
Erica A. Golemis Fox Chase Cancer Center
David J. Mooney
David J. Mooney Harvard University
Wafik S. El-Deiry
Wafik S. El-Deiry Brown University
Klaus M. Hahn
Klaus M. Hahn University of North Carolina at Chapel Hill
Robert G. Uzzo
Robert G. Uzzo Fox Chase Cancer Center
Vivek B. Shenoy
Vivek B. Shenoy University of Pennsylvania

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