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Andres J. P. Klein-Szanto

Andres J. P. Klein-Szanto

D-Index & Metrics

Medicine

D-Index
112
Citations
37125
World Ranking
5203
National Ranking
2813

Overview

Andres J. P. Klein-Szanto is affiliated with the Fox Chase Cancer Center in the United States. Their research spans multiple areas, focusing primarily on medicine, biochemistry, genetics, and molecular biology. Within these broad fields, their work is notably concentrated in molecular biology, oncology, surgery, cancer research, and pulmonary and respiratory medicine.

Their research topics include eosinophilic esophagitis, esophageal cancer research and treatment, cancer cells and metastasis, cancer related to hypoxia and metabolism, epigenetics and DNA methylation, IL-33, ST2, and ILC pathways, and eosinophilic disorders and syndromes.

Notable frequent co-authors collaborating with Andres J. P. Klein-Szanto are:

  • Masataka Shimonosono
  • Hiroshi Nakagawa
  • Anil K. Rustgi
  • Samuel Flashner
  • Kelly A. Whelan

Their publications appear regularly in prominent scientific journals. The most frequent venues include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • Nature Communications
  • Biomolecules

Selected recent papers by Andres J. P. Klein-Szanto include:

  • "Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression," 2020, Cancer Discovery
  • "Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids," 2020, Current Protocols in Stem Cell Biology
  • "Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway," 2021, Nature Communications
  • "p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression," 2023, Cancer Discovery
  • "Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes," 2020, PLoS ONE

Best Publications

  • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

    Huang Q;Gumireddy K;Schrier M;le Sage C

  • The Protein Kinase Akt Induces Epithelial Mesenchymal Transition and Promotes Enhanced Motility and Invasiveness of Squamous Cell Carcinoma Lines

    Sylvia Julien Grille;Alfonso Bellacosa;John Upson;Andres J. Klein-Szanto

  • Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

    Jacky G. Goetz;Susana Minguet;Inmaculada Navarro-Lérida;Juan José Lazcano

  • SKIN TUMOR-PROMOTING ACTIVITY OF BENZOYL PEROXIDE, A WIDELY USED FREE RADICAL-GENERATING COMPOUND

    T. J. Slaga;A. J. P. Klein-Szanto;L. L. Triplett;L. P. Yotti

  • Clinical Implications of Fibroblast Activation Protein in Patients with Colon Cancer

    Leonard R. Henry;Hyung-Ok Lee;John S. Lee;Andres Klein-Szanto

  • AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

    Deborah A Altomare;Hui Qin Wang;Kristine L Skele;Assunta De Rienzo

  • High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas

    Albert B. Bianchi;Shin-Ichiro Mitsunaga;Jin Quan Cheng;Walter M. Klein

  • Phosphorylation-Dependent Ubiquitination of Cyclin D1 by the SCFFBX4-αB Crystallin Complex

    Douglas I. Lin;Olena Barbash;K.G. Suresh Kumar;Jason D. Weber

  • Increased expression of stem cell markers in malignant melanoma

    Walter M Klein;Bryan P Wu;Shuping Zhao;Hong Wu

  • Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors

    Stephen I. Rudnick;Jianlong Lou;Calvin C. Shaller;Yong Tang

  • Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

    Binaifer R. Balsara;Jianming Pei;Yasuhiro Mitsuuchi;Robert Page

  • Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

    Venugopal Radjendirane;Pius Joseph;Ying Hue Lee;Shioko Kimura

  • Mitochondria‐to‐nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

    Govindasamy Amuthan;Gopa Biswas;Shi‐Yu Zhang;Andres Klein‐Szanto

  • The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.

    Tanguy Y. Seiwert;Ramasamy Jagadeeswaran;Leonardo Faoro;Varalakshmi Janamanchi

  • Analysis of the MRP4 Drug Resistance Profile in Transfected NIH3T3 Cells

    Kun Lee;Andres J. P. Klein-Szanto;Gary D. Kruh

  • Nipple aspirate fluid: a promising non-invasive method to identify cellular markers of breast cancer risk.

    E. R. Sauter;E. Ross;M. Daly;A. Klein-Szanto

  • Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck

    Shi Yu Zhang;Andres J P Klein-Szanto;Edward R. Sauter;Marianna Shafarenko

  • Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types.

    Bianchi Ab;Hara T;Ramesh;Gao J

  • Proprotein convertases: “Master switches” in the regulation of tumor growth and progression

    Daniel E. Bassi;Jian Fu;Ricardo Lopez de Cicco;Andres J.P. Klein-Szanto

  • Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression

    Traci Lifsted;Thomas Le Voyer;Max Williams;William Muller

Frequent Co-Authors

Anil K. Rustgi
Anil K. Rustgi Columbia University
J. Alan Diehl
J. Alan Diehl Case Western Reserve University
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Joseph R. Testa
Joseph R. Testa Fox Chase Cancer Center
Phyllis A. Gimotty
Phyllis A. Gimotty University of Pennsylvania
Gary W. Falk
Gary W. Falk University of Pennsylvania
Jonathan M. Spergel
Jonathan M. Spergel University of Pennsylvania
Edna Cukierman
Edna Cukierman Fox Chase Cancer Center
Shoji Natsugoe
Shoji Natsugoe Kagoshima University
Jorge Caamano
Jorge Caamano University of Birmingham

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