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Biology and Biochemistry

D-Index
76
Citations
37305
World Ranking
4925
National Ranking
2365

Overview

Phyllis A. Gimotty is affiliated with the University of Pennsylvania in the United States and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans a range of specialized subfields including oncology, immunology, molecular biology, epidemiology, and infectious diseases.

The scientist's work addresses critical areas such as CAR-T cell therapy research, cutaneous melanoma detection and management, cancer immunotherapy and biomarkers, immunotherapy and immune responses, head and neck cancer studies, immune cell function and interaction, and T-cell and B-cell immunology.

Phyllis A. Gimotty has published multiple recent papers, reflecting ongoing research activity across oncology and immunology topics. Some notable recent publications include:

  • Activating a collaborative innate-adaptive immune response to control metastasis (2021, Cancer Cell)
  • Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers (2020, JAMA Internal Medicine)
  • Stiff matrix induces exosome secretion to promote tumour growth (2023, Nature Cell Biology)
  • ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression (2022, Developmental Cell)
  • PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma (2020, JCI Insight)

The frequent collaborators of Phyllis A. Gimotty include Ravi K. Amaravadi, Giorgos C. Karakousis, Tara C. Mitchell, Devraj Basu, and Robert M. Brody. These coauthors have worked together repeatedly, suggesting established research partnerships in their respective domains.

The venues where Phyllis A. Gimotty most commonly publishes work comprise a range of oncology and biomedical journals. Prominent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Annals of Surgical Oncology
  • Transplantation and Cellular Therapy
  • Blood

Best Publications

  • Final Version of 2009 AJCC Melanoma Staging and Classification

    Charles M. Balch;Jeffrey E. Gershenwald;Seng Jaw Soong;John F. Thompson

  • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

    Lin Zhang;Jose R. Conejo-Garcia;Dionyssios Katsaros;Phyllis A. Gimotty

  • Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T reg cells

    Andrea Facciabene;Xiaohui Peng;Ian S. Hagemann;Klara Balint

  • Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

    Jessie Villanueva;Adina Vultur;John T. Lee;Rajasekharan Somasundaram

  • Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.

    Jean Albrengues;Mario Anthonio Shields;David Ng;Chun Gwon Park

  • microRNAs exhibit high frequency genomic alterations in human cancer

    Lin Zhang;Jia Huang;Nuo Yang;Joel Greshock

  • A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

    Alexander Roesch;Mizuho Fukunaga-Kalabis;Elizabeth C. Schmidt;Susan E. Zabierowski

  • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

    Huang Q;Gumireddy K;Schrier M;le Sage C

  • Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

    Denarda Dangaj;Marine Bruand;Alizée J. Grimm;Catherine Ronet

  • Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

    Hervé Tiriac;Pascal Belleau;Dannielle D Engle;Dennis Plenker

  • Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

    Alexander Roesch;Adina Vultur;Ivan Bogeski;Huan Wang

  • Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

    Lin Zhang;Stefano Volinia;Tomas Bonome;George Adrian Calin

  • Evolution of sleep quantity, sleep deprivation, mood disturbances, empathy, and burnout among interns.

    Ilene M Rosen;Phyllis A Gimotty;Judy A Shea;Lisa M Bellini

  • Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.

    Ronald J Buckanovich;Ronald J Buckanovich;Andrea Facciabene;Sarah Kim;Fabian Benencia

  • Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis

    Adam Cuker;Phyllis A. Gimotty;Mark A. Crowther;Theodore E. Warkentin

  • Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

    Hongxia Z. Imtiyaz;Emily P. Williams;Michele M. Hickey;Shetal A. Patel

  • Prognostic Significance of Mitotic Rate in Localized Primary Cutaneous Melanoma: An Analysis of Patients in the Multi-Institutional American Joint Committee on Cancer Melanoma Staging Database

    John F. Thompson;Seng Jaw Soong;Charles M. Balch;Jeffrey E. Gershenwald

  • Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

    Suresh M. Kumar;Shujing Liu;Hezhe Lu;Hongtao Zhang

  • Delayed neuropathology after carbon monoxide poisoning is immune-mediated

    Stephen R. Thom;Veena M. Bhopale;Donald Fisher;Jie Zhang

  • CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer

    Tomoe Higuchi;Dallas B. Flies;Nicole A. Marjon;Gina Mantia-Smaldone

Frequent Co-Authors

George Coukos
George Coukos Cornell University
David E. Elder
David E. Elder Hospital of the University of Pennsylvania
Xiaowei Xu
Xiaowei Xu University of Pennsylvania
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Lynn M. Schuchter
Lynn M. Schuchter University of Pennsylvania
Anil K. Rustgi
Anil K. Rustgi Columbia University
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Douglas L. Fraker
Douglas L. Fraker University of Pennsylvania
Lin Zhang
Lin Zhang University of Pennsylvania
J. Alan Diehl
J. Alan Diehl Case Western Reserve University

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