World's Best Scientists 2026 revealed!

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Genetics

D-Index
103
Citations
37158
World Ranking
682
National Ranking
345

Molecular Biology

D-Index
103
Citations
37158
World Ranking
478
National Ranking
268

Medicine

D-Index
103
Citations
37356
World Ranking
7395
National Ranking
3867

Research.com Recognitions

  • 2011 - Karl Landsteiner Memorial Award, American Association of Blood Banks (AABB)
  • 2011 - Member of the National Academy of Medicine (NAM)
  • 1993 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1993 - Fellow of the American Academy of Arts and Sciences
  • 1986 - Fellow, The World Academy of Sciences
  • 1986 - Member of the National Academy of Sciences
  • 1984 - Canada Gairdner International Award
  • 1981 - Fellow of the Royal Society, United Kingdom
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences

Overview

Yuet Wai Kan is affiliated with the University of California, San Francisco in the United States. Their research spans across several domains within biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to molecular biology, with notable work in genetic engineering and pluripotent stem cell research.

Their research topics include:

  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • HIV Research and Treatment
  • Nanoplatforms for Cancer Theranostics
  • Trace Elements in Health
  • Alzheimer's Disease Research and Treatments
  • Drug Transport and Resistance Mechanisms

Yuet Wai Kan's work has been published in several venues, among which the most frequent are:

  • Biomedicine & Pharmacotherapy
  • AIDS
  • British Journal of Haematology
  • Brain and Behavior
  • Frontiers in Genome Editing

Notable recent publications include:

  • "Genetically-edited induced pluripotent stem cells derived from HIV-1-infected patients on therapy can give rise to immune cells resistant to HIV-1 infection," 2020, published in AIDS
  • "Induction of therapeutic levels of HbF in genome-edited primary β039-thalassaemia haematopoietic stem and progenitor cells," 2020, published in British Journal of Haematology
  • "Cuproptosis and copper as potential mechanisms and intervention targets in Alzheimer's disease," 2025, published in Biomedicine & Pharmacotherapy
  • "Genetically edited CD34 + cells derived from human iPS cells in vivo but not in vitro engraft and differentiate into HIV-resistant cells," 2021, published in Proceedings of the National Academy of Sciences
  • "Baihui-Penetrating-Qubin Acupuncture Attenuates Neurological Deficits Through SIRT1/FOXO1 Reducing Oxidative Stress and Neuronal Apoptosis in Intracerebral Hemorrhage Rats," 2024, published in Brain and Behavior

Frequent collaborators of Yuet Wai Kan include:

  • Jiaming Wang
  • Zhuo Wang
  • Fernando Teque
  • Maelig Morvan
  • Jay A. Levy

Their recognized scientific contributions have been acknowledged through various awards and memberships:

  • Member of the National Academy of Medicine (NAM), 2011
  • Karl Landsteiner Memorial Award, American Association of Blood Banks (AABB), 2011
  • Fellow of the American Association for the Advancement of Science (AAAS), 1993
  • Fellow of the American Academy of Arts and Sciences, 1993
  • Member of the National Academy of Sciences, 1986
  • Fellow, The World Academy of Sciences, 1986
  • Canada Gairdner International Award, 1984
  • Fellow of the Royal Society, United Kingdom, 1981
  • Member of the Association of American Physicians
  • Foreign Member, Chinese Academy of Sciences

Best Publications

  • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

    P. Moi;K. Chan;I. Asunis;A. Cao

  • The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

    Yousuke Ebina;Leland Ellis;Kurt Jarnagin;Marc Edery

  • Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis

    Jong-Min Lee;Marcus J. Calkins;Kaimin Chan;Yuet Wai Kan

  • An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen.

    Kaimin Chan;Xiao-Dong Han;Yuet Wai Kan

  • Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation

    Yuet Wai Kan;Andree M. Dozy

  • Nrf2 is essential for protection against acute pulmonary injury in mice

    Kaimin Chan;Yuet Wai Kan

  • Rapid duplication and loss of genes coding for the alpha chains of hemoglobin

    E. A. Zimmer;S. L. Martin;Stephen Beverley;Y. W. Kan

  • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease : Critical role for the astrocyte

    Pei Chun Chen;Marcelo R. Vargas;Amar K. Pani;Richard J. Smeyne

  • Tissue-specific targeting of retroviral vectors through ligand-receptor interactions.

    Noriyuki Kasahara;Andrée M. Dozy;Yuet Wai Kan

  • Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac

    Fei Xie;Lin Ye;Judy C. Chang;Ashley I. Beyer

  • Antenatal Diagnosis of Sickle-Cell Anaemia by D. N. A. Analysis of Amniotic-Fluid Cells

    Yuet Wai Kan;AndrÉe M. Dozy

  • Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast.

    Jefferson Y. Chan;Xiao-Liang Han;Yuet Wai Kan

  • Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

    Lin Ye;Jiaming Wang;Ashley I. Beyer;Fernando Teque

  • Nrf2 Transcription Factor, a Novel Target of Keratinocyte Growth Factor Action Which Regulates Gene Expression and Inflammation in the Healing Skin Wound

    Susanne Braun;Christine Hanselmann;Marcus G. Gassmann;Ulrich A. Auf dem Keller

  • Targeted disruption of the ubiquitous CNC‐bZIP transcription factor, Nrf‐1, results in anemia and embryonic lethality in mice

    Jefferson Y. Chan;Mandy Kwong;Ronghua Lu;Judy Chang

  • Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood.

    Mei-Chi Cheung;James D. Goldberg;Yuet Wai Kan

  • Detection of specific DNA sequences by fluorescence amplification: a color complementation assay.

    Farid F. Chehab;Y. W. Kan

  • Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription

    Marcus J. Calkins;Rebekah J. Jakel;Delinda A. Johnson;Kaimin Chan

  • beta 0 thalassemia, a nonsense mutation in man

    Judy C. Chang;Yuet Wai Kan

  • Methods and compositions for targeting specific tissue

    Yuet Wai Kan;Noriyuki Kasahara

Frequent Co-Authors

David G. Nathan
David G. Nathan Harvard University
Antonio Cao
Antonio Cao University of Cagliari
Stephen A. Liebhaber
Stephen A. Liebhaber University of Pennsylvania
Marcus O. Muench
Marcus O. Muench University of California, San Francisco
Narla Mohandas
Narla Mohandas New York Blood Center
William Grossman
William Grossman University of California, San Francisco
Jefferson Y. Chan
Jefferson Y. Chan University of Illinois at Urbana-Champaign
Tom F. Lue
Tom F. Lue University of California, San Francisco
Noriyuki Kasahara
Noriyuki Kasahara University of California, San Francisco
Douglas V. Faller
Douglas V. Faller Takeda (Japan)

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