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Douglas V. Faller

Douglas V. Faller

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
23299
World Ranking
4296
National Ranking
279

Overview

Douglas V. Faller is affiliated with Takeda (Japan) in Japan and has a substantial body of research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work encompasses a significant focus on specialized subfields including Molecular Biology, Hematology, Oncology, Genetics, and Pulmonary and Respiratory Medicine.

Their research covers a range of topics, notably acute myeloid leukemia, protein degradation and inhibitors, histone deacetylase inhibitors, ubiquitin and proteasome pathways, amyloidosis with emphasis on diagnosis, treatment, and outcomes, myeloproliferative neoplasms, and multiple myeloma research and treatments.

Frequent coauthors collaborating with Douglas V. Faller include Robert J. Fram, Lionel Adès, Mikkael A. Sekeres, Farhad Sedarati, and María Diez-Campelo.

Notable recent publications by Douglas V. Faller include:

  • Pevonedistat plus azacitidine vs azacitidine alone in higher-risk MDS/chronic myelomonocytic leukemia or low-blast-percentage AML, 2022, Blood Advances
  • Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML, 2021, Leukemia
  • Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer, 2020, British Journal of Cancer
  • Global epidemiology of amyloid light-chain amyloidosis, 2022, Orphanet Journal of Rare Diseases
  • A randomized phase 3 study of ixazomib-dexamethasone versus physician's choice in relapsed or refractory AL amyloidosis, 2021, Leukemia

Douglas V. Faller's work is frequently published in venues such as Blood, Journal of Clinical Oncology, Leukemia, Gynecologic Oncology, and Clinical Lymphoma Myeloma & Leukemia. The scientist has contributed to Blood with 10 publications and has multiple works appearing in the Journal of Clinical Oncology (5), Leukemia (3), Gynecologic Oncology (3), and Clinical Lymphoma Myeloma & Leukemia (3).

Best Publications

  • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells.

    Nancy C. Andrews;Douglas V. Faller

  • Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

    S Kourembanas;P A Marsden;L P McQuillan;D V Faller

  • Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia.

    S Kourembanas;L P McQuillan;G K Leung;D V Faller

  • A Short-Term Trial of Butyrate to Stimulate Fetal-Globin-Gene Expression in the β-Globin Disorders

    S. P. Perrine;G. D. Ginder;D. V. Faller;G. H. Dover

  • Neutral amino acids in the brain: changes in response to food ingestion.

    John D. Fernstrom;Douglas V. Faller

  • Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells.

    S Kourembanas;R L Hannan;D V Faller

  • Endothelial cell responses to hypoxic stress.

    Douglas V Faller

  • SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis

    V Byles;L Zhu;J D Lovaas;L K Chmilewski

  • Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease.

    George F. Atweh;Millicent Sutton;Imad Nassif;Vassiliki Boosalis

  • A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies.

    Susan P. Perrine;Olivier Hermine;Trudy Small;Felipe Suarez

  • Interleukin 1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor.

    C. A. Sieff;Schickwann Tsai;D. V. Faller

  • Characterization and mapping of RNase T1-resistant oligonucleotides derived from the genomes of Akv and MCF murine leukemia viruses.

    Jean Rommelaere;Douglas V. Faller;Nancy Hopkins

  • Dose-intensive melphalan with blood stem cell support for the treatment of AL amyloidosis: one-year follow-up in five patients

    Raymond L. Comenzo;Evan Vosburgh;Robert W. Simms;Peter Bergethon

  • Delay in the fetal globin switch in infants of diabetic mothers.

    Susan P. Perrine;Michael F. Greene;Douglas V. Faller

  • You bet-cha: a novel family of transcriptional regulators.

    Florence B;Faller Dv

  • RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F.

    Gerald V. Denis;Cyrus Vaziri;Ning Guo;Douglas V. Faller

  • Short-Chain Fatty Acid Inhibitors of Histone Deacetylases: Promising Anticancer Therapeutics?

    James S. Chen;Douglas V. Faller;Remco A. Spanjaard

  • Relative contribution of the leukocyte molecules Mo1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific.

    M. Amin Arnaout;Lewis L. Lanier;Douglas V. Faller

  • Medical hyperspectral imaging to facilitate residual tumor identification during surgery.

    Svetlana V Panasyuk;Shi Yang;Douglas V Faller;Duyen Ngo

  • Butyrate histone deacetylase inhibitors.

    Kosta Steliou;Michael S. Boosalis;Susan P. Perrine;José Sangerman

Frequent Co-Authors

Steven J. Burakoff
Steven J. Burakoff Icahn School of Medicine at Mount Sinai
Robert M. Williams
Robert M. Williams Colorado State University
Cyrus Vaziri
Cyrus Vaziri University of North Carolina at Chapel Hill
Stella Kourembanas
Stella Kourembanas Boston Children's Hospital
Barbara A. Miller
Barbara A. Miller Pennsylvania State University
Colin A. Sieff
Colin A. Sieff Harvard University
Yuet Wai Kan
Yuet Wai Kan University of California, San Francisco
David H.K. Chui
David H.K. Chui Boston University
Jean Rommelaere
Jean Rommelaere German Cancer Research Center

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