World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13946
World Ranking
10787
National Ranking
4685

Overview

Colin A. Sieff is affiliated with Harvard University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology with particular attention to molecular biology, physiology, and cell biology as subfields.

The main topics in their work include:

  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Epigenetics and DNA methylation
  • Erythrocyte function and pathophysiology
  • Ion channel regulation and function
  • Hemoglobin structure and function

Sieff has contributed to several research papers, notably:

  • L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry, 2020, Pediatric Blood & Cancer
  • A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies, 2021, Haematologica

Frequent co-authors in their research include:

  • Adrianna Vlachos
  • Evangelia Atsidaftos
  • Mohammad Lutfi Lababidi
  • Ellen Muir
  • Zora R. Rogers

Sieff's publications have appeared mainly in the following journals:

  • Pediatric Blood & Cancer
  • Haematologica

Best Publications

  • Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

    M. A. Goodell;M. Rosenzweig;Hyung Kim;D. F. Marks

  • Hematopoietic growth factors.

    Colin A. Sieff

  • Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

    Andrew L. Kung;Vivienne I. Rebel;Roderick T. Bronson;Lian Ee Ch'ng

  • Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients

    Hanna T. Gazda;Hanna T. Gazda;Mee Rie Sheen;Adrianna Vlachos;Adrianna Vlachos;Valerie Choesmel;Valerie Choesmel

  • Human recombinant granulocyte-macrophage colony-stimulating factor: a multilineage hematopoietin.

    Colin A. Sieff;Stephen G. Emerson;Robert E. Donahue;David G. Nathan

  • Changes in cell surface antigen expression during hemopoietic differentiation.

    C Sieff;D Bicknell;G Caine;J Robinson

  • Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes.

    M A Arnaout;E A Wang;S C Clark;C A Sieff

  • Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia

    Vijay G. Sankaran;Roxanne Ghazvinian;Ron Do;Prathapan Thiru

  • Ribosomal Protein S24 Gene Is Mutated in Diamond-Blackfan Anemia

    Hanna T. Gazda;Agnieszka Grabowska;Lilia B. Merida-Long;Elzbieta Latawiec

  • Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation

    Jean Robinson;Colin Sieff;Domenico Delia;Paul A. W. Edwards

  • Ribosomal Protein Genes RPS10 and RPS26 Are Commonly Mutated in Diamond-Blackfan Anemia

    Leana Doherty;Mee Rie Sheen;Adrianna Vlachos;Adrianna Vlachos;Valerie Choesmel;Valerie Choesmel

  • Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia.

    Jason E. Farrar;Michelle Nater;Emi Caywood;Michael A. McDevitt

  • Interleukin 1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor.

    C. A. Sieff;Schickwann Tsai;D. V. Faller

  • A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

    Haifa H. Jabara;Haifa H. Jabara;Steven E. Boyden;Steven E. Boyden;Janet Chou;Janet Chou;Narayanaswamy Ramesh;Narayanaswamy Ramesh

  • Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease

    Philip L. McCarthy;Sunil Abhyankar;Steven Neben;Gale Newman

  • The Genetic Landscape of Diamond-Blackfan Anemia.

    Jacob C. Ulirsch;Jacob C. Ulirsch;Jeffrey M. Verboon;Jeffrey M. Verboon;Shideh Kazerounian;Michael H. Guo

  • Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity.

    Stephen G. Emerson;Colin A. Sieff;Elizabeth A. Wang;Gordon G. Wong

  • Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.

    JH Antin;BE Bierer;BR Smith;J Ferrara

  • Erratum: Ribosomal Protein Genes RPS10 and RPS26 Are Commonly Mutated in Diamond-Blackfan Anemia (DOI:10.1016/j.ajhg.2009.12.015)

    Leana Doherty;Mee Rie Sheen;Adrianna Vlachos;Valerie Choesmel

  • Ribosomal Protein S24 Gene Is Mutated in Diamond-Blackfan Anemia.

    Hanna Gazda;Agnieszka Grabowska;Lilia Long;Elzbieta Latawiec

Frequent Co-Authors

Alan H. Beggs
Alan H. Beggs Harvard Medical School
David G. Nathan
David G. Nathan Harvard University
Peter E. Newburger
Peter E. Newburger University of Massachusetts Chan Medical School
Pierre-Emmanuel Gleizes
Pierre-Emmanuel Gleizes Federal University of Toulouse Midi-Pyrénées
Charlotte M. Niemeyer
Charlotte M. Niemeyer University of Freiburg
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Stephen G. Emerson
Stephen G. Emerson Columbia University
Vijay G. Sankaran
Vijay G. Sankaran Harvard University
Eric S. Lander
Eric S. Lander Broad Institute

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