World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
67
Citations
11741
World Ranking
2328
National Ranking
174

Overview

Jean Rommelaere is affiliated with the German Cancer Research Center in Germany, with a research focus primarily on virus-based gene therapy and cancer treatment strategies.

Their recent publications cover a range of topics related to oncolytic virotherapy, immune system activation, and cancer therapeutics. Notable papers include:

  • Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (2021, Clinical Cancer Research)
  • Virotherapy in Germany-Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies (2021, Viruses)
  • Parvovirus-Based Combinatorial Immunotherapy: A Reinforced Therapeutic Strategy against Poor-Prognosis Solid Cancers (2021, Cancers)
  • Oncolytic Rodent Protoparvoviruses Evade a TLR- and RLR-Independent Antiviral Response in Transformed Cells (2023, Pathogens)
  • Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma (2021, Journal of Controlled Release)

Their work intersects several fields of study, predominantly:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

With specific subfields including genetics, oncology, animal science and zoology, infectious diseases, and molecular biology.

Key research topics Jean Rommelaere has contributed to are:

  • Virus-based gene therapy research
  • CAR-T cell therapy research
  • Animal Virus Infections Studies
  • Cutaneous lymphoproliferative disorders research
  • Parvovirus B19 Infection Studies
  • Viral-associated cancers and disorders
  • Cancer Research and Treatments

Frequent coauthors collaborating with Rommelaere include:

  • Assia L. Angelova
  • Guy Ungerechts
  • Jürg P. F. Nüesch
  • Barbara Leuchs
  • Christine E. Engeland

They have published in a variety of scientific journals, with multiple contributions to Pathogens and Cancers. Other publication venues include Clinical Cancer Research, Viruses, and Journal of Controlled Release.

Best Publications

  • Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

    Karsten Geletneky;Jacek Hajda;Assia L. Angelova;Barbara Leuchs

  • Characterization and mapping of RNase T1-resistant oligonucleotides derived from the genomes of Akv and MCF murine leukemia viruses.

    Jean Rommelaere;Douglas V. Faller;Nancy Hopkins

  • Antineoplasic activity of parvoviruses

    Jean Rommelaere;Jan J. Cornelis

  • Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

    Karsten Geletneky;Johannes Huesing;Jean Rommelaere;Joerg R Schlehofer

  • Cytosolic Activation of Cathepsins Mediates Parvovirus H-1-Induced Killing of Cisplatin and TRAIL-Resistant Glioma Cells

    Matteo Di Piazza;Carmen Mader;Karsten Geletneky;Marta Herrero Y Calle

  • Oncolytic parvoviruses as cancer therapeutics.

    Jean Rommelaere;Karsten Geletneky;Assia L. Angelova;Assia L. Angelova;Laurent Daeffler

  • Parvovirus H-1-Induced Tumor Cell Death Enhances Human Immune Response In Vitro via Increased Phagocytosis, Maturation, and Cross-Presentation by Dendritic Cells

    Markus H. Moehler;Maja Zeidler;Vanessa Wilsberg;Jan J. Cornelis

  • Induction of Programmed Cell Death by Parvovirus H-1 in U937 Cells: Connection with the Tumor Necrosis Factor Alpha Signalling Pathway

    Béatrice Rayet;José Antonio Lopez-Guerrero;José Antonio Lopez-Guerrero;Jean Rommelaere;Christiane Dinsart

  • Improvement of Gemcitabine-Based Therapy of Pancreatic Carcinoma by Means of Oncolytic Parvovirus H-1PV

    Assia L. Angelova;Marc Aprahamian;Svitlana P. Grekova;Amor Hajri

  • NS-1 and NS-2 proteins may act synergistically in the cytopathogenicity of parvovirus MVMp

    Anne-Nicole Brandenburger;Daniel Legendre;Bernard Avalosse;Jean Rommelaere

  • cis Requirements for the Efficient Production of Recombinant DNA Vectors Based on Autonomous Parvoviruses

    Jurgen Kestler;Bernd Neeb;Sofie Struyf;Jo Van Damme

  • Molecular Pathways: Rodent Parvoviruses—Mechanisms of Oncolysis and Prospects for Clinical Cancer Treatment

    Jürg P.F. Nüesch;Jeannine Lacroix;Antonio Marchini;Jean Rommelaere

  • Transformation-dependent expression of interleukin genes delivered by a recombinant parvovirus.

    Stephen Russell;Anne-Nicole Brandenburger;Claudia C.L. Flemming;Mary K L Collins

  • A model for tumor suppression using H-1 parvovirus.

    Adam Telerman;Marcel Tuynder;Thierry Dupressoir;Bernard Robaye

  • Through Its Nonstructural Protein NS1, Parvovirus H-1 Induces Apoptosis via Accumulation of Reactive Oxygen Species

    Georgi Hristov;Melanie Krämer;Junwei Li;Nazim El-Andaloussi

  • TNF-alpha and the IFN-gamma-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma.

    M Enderlin;Ev Kleinmann;S Struyf;C Buracchi

  • Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models

    Karsten Geletneky;Irina Kiprianova;Irina Kiprianova;Ali Ayache;Regina Koch;Regina Koch

  • Inhibition by Parvovirus H-1 of the Formation of Tumors in Nude Mice and Colonies in Vitro by Transformed Human Mammary Epithelial Cells

    Thierry Dupressoir;Jean-Marc Vanacker;Jan J. Cornelis;Jan J. Cornelis;Nadine Duponchel

  • Oncolytic parvoviruses: from basic virology to clinical applications

    Antonio Marchini;Serena Bonifati;Eleanor M Scott;Assia L Angelova

  • Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses.

    Guy Ungerechts;Sascha Bossow;Barbara Leuchs;Per S Holm

  • Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses H-1 virus and minute virus of mice

    J. J. Cornelis;P. Becquart;N. Duponchel;N. Salome

  • Identification of a Novel Cellular TPR-Containing Protein, SGT, That Interacts with the Nonstructural Protein NS1 of Parvovirus H-1

    Celina Cziepluch;Elisabeth Kordes;Rémy Poirey;Annabel Grewenig

Frequent Co-Authors

Sofie Struyf
Sofie Struyf KU Leuven
Thomas Giese
Thomas Giese Heidelberg University
Silvano Sozzani
Silvano Sozzani Sapienza University of Rome
A. J. Van Der Eb
A. J. Van Der Eb Leiden University
Aurora Pujol
Aurora Pujol Institut d'Investigació Biomédica de Bellvitge
Douglas V. Faller
Douglas V. Faller Takeda (Japan)
Annunciata Vecchi
Annunciata Vecchi Mario Negri Institute for Pharmacological Research
Peter Tattersall
Peter Tattersall Yale University
Jo Van Damme
Jo Van Damme Rega Institute for Medical Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Microbiology in the USA opens doors to diverse career options, many of which can be enhanced with additional online credentials. For those interested in healthcare data management, exploring the best cahiim accredited him programs online is a smart step. These programs ensure graduates are well-prepared to handle medical records and health information systems effectively.

If you prefer a focused and accelerated path, consider earning an accelerated medical billing and coding certificate online. This is ideal for individuals who want to quickly enter the healthcare industry with specialized coding skills that are in high demand.

For those interested in expanding clinical knowledge alongside microbiology, numerous medical programs online offer degrees tailored to various healthcare careers. These programs provide flexibility and access to quality education without the need to attend on-campus classes.

Additionally, pursuing a public health degree is a valuable option. Many accredited institutions feature accredited online mph programs easy to get into, allowing students to broaden their expertise in health policy, epidemiology, and community health while balancing other commitments.

Best Scientists Citing Jean Rommelaere

Trending Scientists

Recently Published Articles