D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 65 Citations 29,258 142 World Ranking 1925 National Ranking 51

Research.com Recognitions

Awards & Achievements

1989 - Member of Academia Europaea

1989 - Robert Koch Prize

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

A. J. Van Der Eb spends much of his time researching Molecular biology, Cell biology, Virology, Gene and Cell culture. His study in Molecular biology is interdisciplinary in nature, drawing from both DNA, Complementary DNA, Nucleotide excision repair, Exon and Transcription. His DNA study incorporates themes from Calcium, Promoter, Infectivity, Adenoviridae and Transformation.

His Cellular proteins study in the realm of Cell biology connects with subjects such as Evasion. His Virology research is multidisciplinary, incorporating perspectives in Heavy chain and MHC class I, Major histocompatibility complex. His Cell culture research is mostly focused on the topic Retrovirus.

His most cited work include:

  • A new technique for the assay of infectivity of human adenovirus 5 DNA. (7472 citations)
  • Transformation of rat cells by DNA of human adenovirus 5 (570 citations)
  • MDMX: a novel p53-binding protein with some functional properties of MDM2. (500 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Molecular biology, Gene, Cell culture, Virology and DNA. His Molecular biology research is multidisciplinary, relying on both Gene expression, Transfection, Virus, Messenger RNA and Transcription. Within one scientific family, A. J. Van Der Eb focuses on topics pertaining to Adenosine deaminase under Gene, and may sometimes address concerns connected to Severe combined immunodeficiency.

His Cell culture study integrates concerns from other disciplines, such as Growth factor, Adenoviridae, Mutant and Cell biology. His work deals with themes such as Mutagenesis, Human Adenoviruses and Genetic enhancement, which intersect with Virology. His DNA study combines topics from a wide range of disciplines, such as Calcium, Mutation, Molecular mass, Antigen and Transformation.

He most often published in these fields:

  • Molecular biology (57.23%)
  • Gene (26.01%)
  • Cell culture (25.43%)

What were the highlights of his more recent work (between 1993-2013)?

  • Molecular biology (57.23%)
  • Cell biology (19.65%)
  • Cancer research (13.87%)

In recent papers he was focusing on the following fields of study:

Molecular biology, Cell biology, Cancer research, Virology and Transcription factor are his primary areas of study. The concepts of his Molecular biology study are interwoven with issues in Transfection, Complementary DNA, Gene, Transcription and Gene isoform. A. J. Van Der Eb has researched Gene in several fields, including DNA and Wilms' tumor.

His studies deal with areas such as Cyclin-dependent kinase, Cellular differentiation, Cell culture and Transformation as well as Cell biology. In the subject of general Cell culture, his work in Primary cell is often linked to P70 s6 kinase, thereby combining diverse domains of study. When carried out as part of a general Virology research project, his work on Virus, Chicken anaemia virus and Replication is frequently linked to work in Bead, therefore connecting diverse disciplines of study.

Between 1993 and 2013, his most popular works were:

  • MDMX: a novel p53-binding protein with some functional properties of MDM2. (500 citations)
  • Cyclin D1 is an essential mediator of apoptotic neuronal cell death. (353 citations)
  • A single chicken anemia virus protein induces apoptosis. (218 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His main research concerns Cancer research, Molecular biology, Transcription, Cell biology and Apoptosis. Molecular biology is closely attributed to Gene in his study. A. J. Van Der Eb interconnects Cyclin-dependent kinase, Cellular differentiation, Retinoblastoma protein and MDMX in the investigation of issues within Cell biology.

His biological study spans a wide range of topics, including Virus, Cell culture, Transfection and Cancer gene. His Virus study combines topics in areas such as Adenoviridae and Suicide gene. He combines subjects such as Immunogold labelling and Peripheral blood mononuclear cell with his study of Cell culture.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A new technique for the assay of infectivity of human adenovirus 5 DNA.

F.L. Graham;A.J. van der Eb.
Virology (1973)

12425 Citations

Transformation of rat cells by DNA of human adenovirus 5

F.L. Graham;A.J. Van Der Eb.
Virology (1973)

902 Citations

MDMX: a novel p53-binding protein with some functional properties of MDM2.

A. Shvarts;W. T. Steegenga;N. Riteco;T. Van Laar.
The EMBO Journal (1996)

705 Citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

P.I. Schrier;R.A. Bernards;R.T.M.J. Vaessen;A. Houweling.
Nature (1983)

642 Citations

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

O. Kranenburg;A. J. Van Der Eb;Alt Zantema.
The EMBO Journal (1996)

542 Citations

Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

H. Van Dam;M. Duyndam;R. Rottier;A. Bosch.
The EMBO Journal (1993)

501 Citations

Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells

A. A. A. M. Danen-Van Oorschot;D. F. Fischer;J. M. Grimbergen;B. Klein.
Proceedings of the National Academy of Sciences of the United States of America (1997)

395 Citations

Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity.

R.A. Bernards;P.I. Schrier;A. Houweling;J.L. Bos.
Nature (1983)

390 Citations

Insulin stimulation of gene expression mediated by p21ras activation.

B. M. T. Burgering;R. H. Medema;J. A. Maassen;M. L. Van De Wetering.
The EMBO Journal (1991)

363 Citations

[75] Assay of transforming activity of tumor virus DNA

A.J. van der Eb;F.L. Graham.
Methods in Enzymology (1980)

363 Citations

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