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Genetics

D-Index
53
Citations
13189
World Ranking
3716
National Ranking
131

Overview

P. Meera Khan was affiliated with Leiden University in the Netherlands. Their research contributions spanned multiple areas within medicine and biochemistry, genetics, and molecular biology. Over their career, they published extensively with a focus on metabolism, diabetes, cancer, liver disease diagnosis and treatment, and bone health.

The scientist's publication record included research articles addressing key topics such as metabolism, diabetes management, ovarian function disorders, and bone metabolism and diseases. Their work was disseminated through various reputable venues, including:

  • Expert Opinion on Pharmacotherapy
  • Journal of Diabetes & Metabolic Disorders
  • Biochemical and Biophysical Research Communications
  • European Journal of Clinical Pharmacology
  • Clinical Epidemiology and Global Health

Representative recent papers authored by P. Meera Khan included the following:

  • "Impact of tofogliflozin on hepatic outcomes: a systematic review," 2023, European Journal of Clinical Pharmacology
  • "CTX-1 and TRACP-5b as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study," 2024, Journal of Diabetes & Metabolic Disorders
  • "A systematic review on effect of sodium-glucose cotransporter-2 inhibitors on the metabolic and endocrinological profile of patients with polycystic ovarian syndrome," 2024, Expert Opinion on Pharmacotherapy
  • "A systematic review and meta-analysis on efficacy and safety of Ganaxolone in epilepsy," 2024, Expert Opinion on Pharmacotherapy
  • "Neuroprotective effect of naringin by modulation of klotho and HMGB1-TLR4 axis in PTZ-induced kindling in mice," 2024, Biochemical and Biophysical Research Communications

The scientist collaborated frequently with several coauthors. Among the most prolific were:

  • Nidhi Agarwal
  • Rizwana Parveen
  • Haya Majid
  • M.A. Pathak
  • Nilanjan Saha

Their main fields of study included medicine and biochemistry, genetics, and molecular biology. Subfields of particular focus were molecular biology, oncology, epidemiology, surgery, and endocrinology, diabetes, and metabolism.

Major thematic topics covered by their research featured:

  • Metabolism, diabetes, and cancer
  • Liver disease diagnosis and treatment
  • Diabetes treatment and management
  • Bone health and osteoporosis research
  • Bone metabolism and diseases
  • Bone health and treatments
  • Ovarian function and disorders

Best Publications

  • The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).

    H. F. A. Vasen;J. P. Mecklin;P. Meera Khan;H. T. Lynch

  • Report of the committee on the genetic constitution of autosomes other than chromosomes 1,2 and 6.

    F.H. Ruddle;P. Meera Khan

  • Clinical findings with implications for genetic testing in families with clustering of colorectal cancer.

    JT Wijnen;Hfa Vasen;PM Khan;AH Zwinderman

  • Enzyme electrophoresis on cellulose acetate gel: Zymogram patterns in man-mouse and man-Chinese hamster somatic cell hybrids

    P. Meera Khan

  • Rapid Detection of Translation-Terminating Mutations at the Adenomatous Polyposis Coli (APC) Gene by Direct Protein Truncation Test

    Rob van der Luijt;P.Meera Khan;Hans Vasen;Claus van Leeuwen

  • Interval cancers in hereditary non-polyposis colorectal cancer (Lynch syndrome)

    H.F.A. Vasen;F.M. Nagengast;P. Meera Khan

  • Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

    Ron Smits;Menno F. Kielman;Cor Breukel;Chris Zurcher

  • At least four different chromosomal regions are involved in loss of heterozygosity in human breast carcinoma.

    Peter Devilee;Marianne van den Broek;Nel Kuipers-Dukshoorn;Rukmini Kolluri

  • Molecular genetic tests as a guide to surgical management of familial adenomatous polyposis

    Hfa Vasen;RB van der Luijt;Jfm Slors;E Buskens

  • A cost-effectiveness analysis of colorectal screening of hereditary nonpolyposis colorectal carcinoma gene carriers.

    Hans F. A. Vasen;Marjolein van Ballegooijen;Eric Buskens;Jan K. Kleibeuker

  • Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.

    Juul Wijnen;P. Meera Khan;Hans Vasen;Heleen van der Klift

  • Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli

    R. B. van der Luijt;P. Meera Khan;Hans F. A. Vasen;C. Breukel

  • Loss of human genetic markers in man--Chinese hamster somatic cell hybrids.

    A. Westerveld;R. P. L. S. Visser;P. Meera Khan;D. Bootsma

  • Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germline mutations identified by DGGE, PTT, and southern analysis.

    Rob. B. van der Luijt;P. Meera Khan;Hans F. A. Vasen;Carli M. J. Tops

  • ENZYME ELECTROPHORESIS ON CELLULOSE ACETATE GEL. II. ZYMOGRAM PATTERNS IN MAN-CHINESE HAMSTER SOMATIC CELL HYBRIDS

    Harry van Someren;Hans Beijersbergen van Henegouwen;Wilbert Los;Elisabetta Wurzer-Figurelli

  • Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci.

    H. Van Someren;A. Westerveld;A. Hagemeijer;J. R. Mees

  • Surveillance in hereditary nonpolyposis colorectal cancer: An international cooperative study of 165 families

    Hans F. Vasen;Jukka Pekka Mecklin;Patrice Watson;Joji Utsunomiya

  • APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis

    R. B. Van Der Luijt;H. F. A. Vasen;C. M. J. Tops;C. Breukel

  • The value of screening and central registration of families with familial adenomatous polyposis. A study of 82 families in The Netherlands.

    H. F. A. Vasen;G. Griffioen;G. Griffioen;G. J. A. Offerhaus;G. J. A. Offerhaus;F. C. A. Den Hartog Jager;F. C. A. Den Hartog Jager

  • Apc1638N: A mouse model for familial adenomatous polyposis–associated desmoid tumors and cutaneous cysts

    Ron Smits;Willemien van der Houven van Oordt;Arne Luz;Chris Zurcher

Frequent Co-Authors

Andries Westerveld
Andries Westerveld University of Amsterdam
Peter L. Pearson
Peter L. Pearson Universidade de São Paulo
Dirk Bootsma
Dirk Bootsma Erasmus University Rotterdam
Hans F. A. Vasen
Hans F. A. Vasen Leiden University
Riccardo Fodde
Riccardo Fodde Erasmus MC
Thomas B. Shows
Thomas B. Shows Roswell Park Cancer Institute
Stephen J. O'Brien
Stephen J. O'Brien Nova Southeastern University
Frank H. Ruddle
Frank H. Ruddle Yale University
Malcolm A. Ferguson-Smith
Malcolm A. Ferguson-Smith University of Cambridge
Victor A. McKusick
Victor A. McKusick Johns Hopkins University School of Medicine

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