Frank L. Graham

Research.com Recognitions

• 2023 - Research.com Microbiology in Canada Leader Award
• 2022 - Research.com Microbiology in Canada Leader Award
• 1999 - Fellow of the Royal Society of Canada Academy of Science

Overview

Best Publications

• A new technique for the assay of infectivity of human adenovirus 5 DNA.

  F.L. Graham;A.J. van der Eb

  15276
  Citations

• Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

  F. L. Graham;J. Smiley;W. C. Russell;R. Nairn

  6925
  Citations

• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

  P J Sime;Z Xing;F L Graham;K G Csaky

  1275
  Citations

• Manipulation of adenovirus vectors.

  Frank L. Graham;Ludvik Prevec

  1256
  Citations

• An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3

  Andrew J. Bett;Wael Haddara;Ludvik Prevec;Frank L. Graham

  1200
  Citations

• Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells.

  Gerry Shaw;Silas Morse;Miguel Ararat;Frank L. Graham

  1048
  Citations

• Transformation of rat cells by DNA of human adenovirus 5

  F.L. Graham;A.J. Van Der Eb

  984
  Citations

• A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal

  Robin J. Parks;Liane Chen;Martina Anton;Uma Sankar

  957
  Citations

• A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

  W.J. McGrory;D.S. Bautista;F.L. Graham

  953
  Citations

• Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

  Gudrun Schiedner;Núria Morral;Núria Morral;Robin J. Parks;Ying Wu

  892
  Citations

• Packaging capacity and stability of human adenovirus type 5 vectors.

  A J Bett;L Prevec;F L Graham

  768
  Citations

• A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

  Ian A. York;Cindy Roop;David W. Andrews;Stanley R. Riddell

  744
  Citations

• Methods for construction of adenovirus vectors.

  Frank L. Graham;Ludvik Prevec

  740
  Citations

• An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene

  M. A. Morsy;M. Gu;S. Motzel;Jing Zhao

  568
  Citations

• Adenovirus vectors for gene therapy

  Frank L. Graham;Martina Anton;Michael A. Rudnicki

  529
  Citations

• Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

  Núria Morral;Wanda O’Neal;Karen Rice;Michele Leland

  505
  Citations

• Host-range mutants of adenovirus type 5 defective for growth in HeLa cells.

  Tim Harrison;Frank Graham;Jim Williams

  442
  Citations

• Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40.

  F. L. Graham;P. J. Abrahams;C. Mulder;H. L. Heijneker

  438
  Citations

• Studies in mouse L-cells on the incorporation of 1-beta-D-arabinofuranosylcytosine into DNA and on inhibition of DNA polymerase by 1-beta-D-arabinofuranosylcytosine 5'-triphosphate.

  F. L. Graham;G. F. Whitmore

  418
  Citations

• Assay of transforming activity of tumor virus DNA.

  A.J. van der Eb;F.L. Graham

  418
  Citations