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Molecular Biology
USA
2025

D-Index & Metrics

Genetics

D-Index
129
Citations
65585
World Ranking
262
National Ranking
136

Molecular Biology

D-Index
129
Citations
65585
World Ranking
192
National Ranking
120

Research.com Recognitions

  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2020 - Fellow, National Academy of Inventors

Overview

Mark A. Kay is affiliated with Stanford University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with notable contributions in Medicine as well. Within these domains, their work focuses on subfields such as Molecular Biology, Genetics, Cancer Research, Oncology, and Epidemiology.

The scientist's research topics include:

  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA Interference and Gene Delivery
  • CAR-T cell therapy research
  • Cancer-related molecular mechanisms research

Mark A. Kay's most frequent publication venues are:

  • Molecular Therapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Therapy - Methods & Clinical Development
  • UNC Libraries

Frequent co-authors include:

  • Katja Pekrun
  • Feijie Zhang
  • Hak Kyun Kim
  • Jianpeng Xu
  • Francesco Puzzo

Notable recent papers authored or co-authored by Mark A. Kay are:

  • Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals, 2020, Nature Methods
  • Evaluating the state of the science for adeno-associated virus integration: An integrated perspective, 2022, Molecular Therapy
  • Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics, 2020, Molecular Therapy
  • A standardized ontology for naming tRNA-derived RNAs based on molecular origin, 2023, Nature Methods
  • RNA structure probing reveals the structural basis of Dicer binding and cleavage, 2021, Nature Communications

Mark A. Kay has been recognized with the award of Fellow, National Academy of Inventors in 2020.

Best Publications

  • Progress and problems with the use of viral vectors for gene therapy

    Clare E. Thomas;Anja Ehrhardt;Mark A. Kay

  • Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

    Manno Cs;Pierce Gf;Arruda Vr;Glader B

  • Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

    Amit C. Nathwani;Edward G.D. Tuddenham;Savita Rangarajan;Cecilia Rosales

  • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.

    Dirk Grimm;Konrad L. Streetz;Konrad L. Streetz;Catherine L. Jopling;Theresa A. Storm

  • Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

    Mark A. Kay;Joseph C Glorioso;Luigi Naldini

  • RNA interference in adult mice.

    Anton P. McCaffrey;Leonard Meuse;Thu-Thao T. Pham;Douglas S. Conklin

  • Long-term safety and efficacy of factor IX gene therapy in hemophilia B

    Amit C Nathwani;Ulreke M Reiss;Edward G D Tuddenham;Cecilia Rosales;Cecilia Rosales

  • Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector

    Mark A. Kay;Catherine S. Manno;Catherine S. Manno;Margaret V. Ragni;Peter J. Larson;Peter J. Larson

  • Inhibition of hepatitis B virus in mice by RNA interference.

    Anton P McCaffrey;Hiroyuki Nakai;Kusum Pandey;Zan Huang

  • A nonviral minicircle vector for deriving human iPS cells

    Fangjun Jia;Kitchener D Wilson;Ning Sun;Deepak M Gupta

  • AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

    Catherine S. Manno;Amy J. Chew;Sylvia Hutchison;Peter J. Larson

  • Robust expansion of human hepatocytes in Fah −/− / Rag2 −/− / Il2rg −/− mice

    Hisaya Azuma;Nicole Paulk;Aarati Ranade;Craig Dorrell

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • State-of-the-art gene-based therapies: the road ahead.

    Mark A. Kay

  • In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

    Dirk Grimm;Joyce S. Lee;Lora Wang;Tushar Desai

  • In vivo activity of nuclease-resistant siRNAs.

    Juliana M. Layzer;Anton P. Mccaffrey;Alice K. Tanner;Zan Huang

  • Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

    R O Snyder;C H Miao;G A Patijn;S K Spratt

  • Human tRNA-derived small RNAs in the global regulation of RNA silencing

    Dirk Haussecker;Yong Huang;Ashley Lau;Poornima Parameswaran

  • Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8

    Katsuya Inagaki;Sally Fuess;Theresa A. Storm;Gregory A. Gibson

  • Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

    Richard O. Snyder;Carol Miao;Leonard Meuse;Julie Tubb

Frequent Co-Authors

Dirk Grimm
Dirk Grimm Heidelberg University
André Lieber
André Lieber University of Washington
Katherine A. High
Katherine A. High Children's Hospital of Philadelphia
Markus Grompe
Markus Grompe Oregon Health & Science University
Andrew Fire
Andrew Fire Stanford University
Milton J. Finegold
Milton J. Finegold Baylor College of Medicine
Joseph C. Wu
Joseph C. Wu Stanford University
Savio L. C. Woo
Savio L. C. Woo Icahn School of Medicine at Mount Sinai
Robert C. Robbins
Robert C. Robbins Stanford University
Jakub Tolar
Jakub Tolar University of Minnesota

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