World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
100
Citations
79060
World Ranking
735
National Ranking
368

Molecular Biology

D-Index
100
Citations
79060
World Ranking
521
National Ranking
288

Research.com Recognitions

  • 2006 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 2006 - Nobel Prize for their discovery of RNA interference - gene silencing by double-stranded RNA
  • 2005 - Canada Gairdner International Award
  • 2004 - Member of the National Academy of Sciences
  • 2004 - Fellow of the American Academy of Arts and Sciences
  • 2004 - Member of the National Academy of Medicine (NAM)
  • 2002 - Genetics Society of America Medal

Overview

Andrew Fire is affiliated with Stanford University in the United States and has a research focus primarily within the field of Biochemistry, Genetics and Molecular Biology. Their work further extends into several subfields including Molecular Biology, Plant Science, Ecology, Virology, and Cellular and Molecular Neuroscience.

Fire's research covers diversified topics with a concentration on areas such as Bacteriophages and microbial interactions, CRISPR and Genetic Engineering, Plant Virus Research Studies, HIV Research and Treatment, RNA and protein synthesis mechanisms, Genetics, Aging, and Longevity in Model Organisms, as well as Planarian Biology and Electrostimulation.

Some of the recent papers authored or co-authored by Andrew Fire include:

  • Doubling of the known set of RNA viruses by metagenomic analysis of an aquatic virome (2020, Nature Microbiology)
  • Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth (2020, Nature Immunology)
  • Intron and gene size expansion during nervous system evolution (2020, BMC Genomics)
  • An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes (2020, mSphere)
  • An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans (2021, Developmental Cell)

Andrew Fire has collaborated frequently with several coauthors, including:

  • Massa J. Shoura
  • Lamia Wahba
  • Dae-Eun Jeong
  • Richard Nelson Hall
  • Matthew J. McCoy

The scientist has published notably in venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, BMC Genomics, Kidney International, and Nature Microbiology.

Throughout their career, Andrew Fire has received multiple recognitions, including:

  • Nobel Prize in 2006 for the discovery of RNA interference - gene silencing by double-stranded RNA
  • Paul Ehrlich and Ludwig Darmstaedter Prize (2006)
  • Canada Gairdner International Award (2005)
  • Fellow of the American Academy of Arts and Sciences (2004)
  • Member of the National Academy of Medicine (NAM) (2004)
  • Member of the National Academy of Sciences (2004)
  • Genetics Society of America Medal (2002)

Best Publications

  • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

    Andrew Fire;SiQun Xu;Mary K. Montgomery;Steven A. Kostas;Steven A. Kostas

  • Specific interference by ingested dsRNA

    Lisa Timmons;Andrew Fire

  • Genetic inhibition of double-stranded RNA

    Andrew Z. Fire;Stephen A. Kostas;Mary K. Montgomery;Lisa Timmons

  • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

    Lisa Timmons;Donald L. Court;Andrew Fire

  • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

    Alla Grishok;Amy E. Pasquinelli;Darryl Conte Jr.;Na Li

  • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems.

    Natasha J. Caplen;Susan Parrish;Farhad Imani;Andrew Fire

  • The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

    Hiroaki Tabara;Madathia Sarkissian;William G. Kelly;Jamie Fleenor

  • On the role of RNA amplification in dsRNA-triggered gene silencing.

    Titia Sijen;Jamie Fleenor;Femke Simmer;Karen L. Thijssen

  • Chapter 19 DNA Transformation

    Craig Mello;Andrew Fire

  • DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract

    James L. Manley;Andrew Fire;Amparo Cano;Phillip A. Sharp

  • Rolling replication of short DNA circles.

    Andrew Fire;Si-Qun Xu

  • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

    Hua-Xin Liao;Rebecca Lynch;Tongqing Zhou;Feng Gao;Feng Gao

  • RNA-triggered gene silencing

    Andrew Fire

  • RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

    Mary K. Montgomery;SiQun Xu;Andrew Fire

  • Functional Anatomy of a dsRNA Trigger: Differential Requirement for the Two Trigger Strands in RNA Interference

    Susan Parrish;Jamie Fleenor;SiQun Xu;Craig Mello

  • A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans.

    Andrew Fire;Susan White Harrison;Dennis Dixon

  • Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans

    Julia Pak;Andrew Fire

  • Efficient Marker-Free Recovery of Custom Genetic Modifications with CRISPR/Cas9 in Caenorhabditis elegans

    Joshua A. Arribere;Ryan T. Bell;Becky X. H. Fu;Karen L. Artiles

  • A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning

    Anton Valouev;Jeffrey Ichikawa;Thaisan Tonthat;Jeremy Stuart

  • Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi.

    Femke Simmer;Marcel Tijsterman;Susan Parrish;Susan Parrish;Sandhya P Koushika

Frequent Co-Authors

Scott D. Boyd
Scott D. Boyd Stanford University
Mark A. Kay
Mark A. Kay Stanford University
Craig C. Mello
Craig C. Mello University of Massachusetts Chan Medical School
Barton F. Haynes
Barton F. Haynes Duke University
Hua-Xin Liao
Hua-Xin Liao Duke University
Garnett Kelsoe
Garnett Kelsoe Duke University
Natasha J. Caplen
Natasha J. Caplen National Institutes of Health
Thomas B. Kepler
Thomas B. Kepler Boston University
Richard A. Morgan
Richard A. Morgan University of California, Los Angeles

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics in the USA can open the door to diverse healthcare careers. For those interested in broader roles, pursuing an mha degree is a cost-effective way to move into healthcare leadership while understanding the genetic landscape impacting patient care.

If you're considering a clinical career, not do all nursing schools require the teas exam. Many programs offer alternate pathways, making nursing education more accessible to a wider range of students—an important consideration for those with genetic counseling interests.

For a quicker entry into the workforce, lpn accelerated program options can help you start your healthcare career swiftly, with some coursework relevant to genetic healthcare and patient needs.

Those aiming for academic or research roles may consider phd nursing programs with a genetics focus. These accessible online PhD degrees can pave the way for genetics research, education, and advanced clinical practice.

Best Scientists Citing Andrew Fire

Trending Scientists