World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
15012
World Ranking
18555
National Ranking
7580

Natasha J. Caplen publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Natasha J. Caplen sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 172 publications — 37th percentile

37% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Natasha J. Caplen D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Natasha J. Caplen sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 47 D-Index — 6th percentile

6% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Natasha J. Caplen is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a significant number of publications in Molecular Biology and Genetics. Caplen's work also spans areas of Pulmonary and Respiratory Medicine, Oncology, and Immunology.

The scientist has contributed extensively to topics such as RNA modifications and cancer, RNA research and splicing, sarcoma diagnosis and treatment, virus-based gene therapy research, RNA and protein synthesis mechanisms, DNA repair mechanisms, and genomics and chromatin dynamics.

Among Caplen's recent papers are:

  • HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript (2022, Nucleic Acids Research)
  • CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma (2020, Molecular Cancer Therapeutics)
  • The HNRNPF/H RNA binding proteins and disease (2023, Wiley Interdisciplinary Reviews - RNA)
  • DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains (2024, The EMBO Journal)
  • The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability (2023, Journal of Cell Science)

Caplen's frequent coauthors include Soumya Sundara Rajan, Tamara L. Jones, Tayvia Brownmiller, Katelyn R. Ludwig, and Raj Chari. This collaboration network highlights interdisciplinary connections within their research projects.

The scientist has published regularly in several scientific venues, with notable frequency in Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Molecular Cancer Therapeutics, Molecular and Cellular Biology, and Nucleic Acids Research.

Best Publications

  • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

    Nozomu Yanaihara;Natasha Caplen;Elise Bowman;Masahiro Seike

  • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems.

    Natasha J. Caplen;Susan Parrish;Farhad Imani;Andrew Fire

  • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

    Natasha J. Caplen;Eric W.F.W. Alton;Peter G. Mddleton;Julia R. Dorin

  • Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

    Peter C. Scacheri;Orit Rozenblatt-Rosen;Natasha J. Caplen;Tyra G. Wolfsberg

  • Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

    E W Alton;P G Middleton;N J Caplen;S N Smith

  • dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference

    Natasha J. Caplen;Jamie Fleenor;Andrew Fire;Richard A. Morgan

  • Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

    Joseph A. Ludwig;Gergely Szakács;Scott E. Martin;Benjamin F. Chu

  • RNAi microarray analysis in cultured mammalian cells.

    Spyro Mousses;Natasha J. Caplen;Robert Cornelison;Don Weaver

  • Defining and assaying RNAi in mammalian cells.

    Konrad Huppi;Scott E. Martin;Natasha J. Caplen

  • p53-Dependent induction of PVT1 and miR-1204.

    Anthony M. Barsotti;Rachel Beckerman;Oleg Laptenko;Konrad Huppi

  • The identification of microRNAs in a genomically unstable region of human chromosome 8q24.

    Konrad Huppi;Natalia Volfovsky;Timothy Runfola;Tamara L. Jones

  • RNAi as a gene therapy approach

    Natasha J Caplen

  • Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference

    Natasha J. Caplen;J. Paul Taylor;Victoria S. Statham;Fumiaki Tanaka

  • In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE

    N. J. Caplen;E. Kinrade;F. Sorgi;X. Gao

  • Applications of RNA interference in mammalian systems.

    Scott E. Martin;Natasha J. Caplen

  • Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response.

    Yong-Wei Zhang;Tamara L. Jones;Scott E. Martin;Natasha J. Caplen

  • The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

    M Stern;NJ Caplen;JE Browning;U Griesenbach

  • Kinase-Independent Functions for Itk in TCR-Induced Regulation of Vav and the Actin Cytoskeleton

    Derek Dombroski;Richard A. Houghtling;Christine M. Labno;Patricia Precht

  • The 8q24 Gene Desert: An Oasis of Non-Coding Transcriptional Activity

    Konrad Huppi;Jason J. Pitt;Brady M. Wahlberg;Natasha J. Caplen

  • Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth

    P. G. Middleton;N. J. Caplen;X. Gao;Leaf Huang

Frequent Co-Authors

Duncan M. Geddes
Duncan M. Geddes Imperial College London
Eric W.F.W. Alton
Eric W.F.W. Alton National Institutes of Health
Lee J. Helman
Lee J. Helman Children's Hospital of Los Angeles
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center
Leaf Huang
Leaf Huang University of North Carolina at Chapel Hill
Thomas Ried
Thomas Ried National Institutes of Health
Yves Pommier
Yves Pommier National Institutes of Health
Olli Kallioniemi
Olli Kallioniemi Karolinska Institute
Robert Williamson
Robert Williamson University of Melbourne
David J. Porteous
David J. Porteous University of Edinburgh

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