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15831
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9582
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688

Overview

Gerhard Eisenbrand is a researcher affiliated with the Technical University of Kaiserslautern in Germany. Their work spans several fields, primarily focusing on Agricultural and Biological Sciences, Biochemistry, Genetics and Molecular Biology, and Environmental Science. These areas encompass diverse aspects of health and environmental research relevant to toxicology and food safety.

The main topics explored in their research include carcinogens and genotoxicity assessment, agricultural safety and regulations, effects and risks of endocrine disrupting chemicals, potato plant research, animal testing and alternatives, pesticide exposure and toxicity, and pesticide residue analysis and safety.

Gerhard Eisenbrand has contributed to numerous publications with a notable focus on venues related to toxicology and food safety. The frequent publication venues include:

  • Food and Chemical Toxicology
  • Archives of Toxicology
  • Toxicology Letters
  • Mutagenesis
  • Critical Reviews in Toxicology

Selected recent papers authored by or including Eisenbrand are:

  • "The BlueScreen HC assay to predict the genotoxic potential of fragrance materials," 2022, Mutagenesis
  • "Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses," 2020, Archives of Toxicology
  • "Mode of action-based risk assessment of genotoxic carcinogens," 2020, Archives of Toxicology
  • "Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure," 2020, Archives of Toxicology
  • "FEMA GRAS assessment of natural flavor complexes: Clove, cinnamon leaf and West Indian bay leaf-derived flavoring ingredients," 2020, Food and Chemical Toxicology

Frequent collaborators in Eisenbrand's research include Ivonne M.C.M. Rietjens, Shoji Fukushima, Nigel J. Gooderham, F. Peter Guengerich, and Stephen S. Hecht. These collaborators have co-authored multiple papers, indicating ongoing partnerships within the fields of toxicology and chemical safety.

Best Publications

  • Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease A PROPERTY COMMON TO MOST CYCLIN-DEPENDENT KINASE INHIBITORS?

    Sophie Leclerc;Matthieu Garnier;Ralph Hoessel;Doris Marko

  • Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases.

    Ralph Hoessel;Sophie Leclerc;Jane A. Endicott;Martin E. M. Nobel

  • Impact of food processing and detoxification treatments on mycotoxin contamination.

    Petr Karlovsky;Michele Suman;Franz Berthiller;Johan De Meester

  • Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine

    Weici Tang;Gerhard Eisenbrand

  • A review on the beneficial aspects of food processing.

    Martinus van Boekel;Vincenzo Fogliano;Nicoletta Pellegrini;Catherine Stanton

  • 5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione.

    C Janzowski;V Glaab;E Samimi;J Schlatter

  • Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

    Sangkil Nam;Ralf Buettner;James Turkson;Donghwa Kim

  • Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine.

    Gerhard Eisenbrand;Frankie Hippe;Sandra Jakobs;Stephan Muehlbeyer

  • Nitrate and nitrite in the diet: How to assess their benefit and risk for human health

    Michael Habermeyer;Angelika Roth;Sabine Guth;Patrick Diel

  • Risk characterisation of chemicals in food and diet.

    A. G. Renwick;S. M. Barlow;Irva Hertz-Picciotto;A. R. Boobis

  • Ochratoxin A: induction of (oxidative) DNA damage, cytotoxicity and apoptosis in mammalian cell lines and primary cells.

    Hennicke G Kamp;Gerhard Eisenbrand;Josef Schlatter;Kirsten Würth

  • Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.

    Sabine Guth;Stephanie Hüser;Angelika Roth;Gisela Degen

  • Food-borne heterocyclic amines. Chemistry, formation, occurrence and biological activities. A literature review.

    G. Eisenbrand;W. Tang

  • An anthocyanin/polyphenolic-rich fruit juice reduces oxidative DNA damage and increases glutathione level in healthy probands.

    Tamara Weisel;Matthias Baum;Gerhard Eisenbrand;Helmut Dietrich

  • Risk assessment of substances that are both genotoxic and carcinogenic: Report of an International Conference organized by EFSA and WHO with support of ILSI Europe

    S. Barlow;A.G. Renwick;J. Kleiner;J.W. Bridges

  • Inhibitor Binding to Active and Inactive CDK2: The Crystal Structure of CDK2-Cyclin A/Indirubin-5-Sulphonate

    Thomas G. Davies;Paul Tunnah;Laurent Meijer;Doris Marko

  • 3′,5′-Cyclic Nucleotide Phosphodiesterase in Tumor Cells as Potential Target for Tumor Growth Inhibition

    Markus Drees;Rainer Zimmermann;Gerhard Eisenbrand

  • Polyphenolic apple juice extracts and their major constituents reduce oxidative damage in human colon cell lines.

    Sandra Schaefer;Matthias Baum;Gerhard Eisenbrand;Helmut Dietrich

  • Estimation of human exposure to styrene and ethylbenzene.

    Weici Tang;Ingrid Hemm;Gerhard Eisenbrand

  • Anthocyanin/Polyphenolic–Rich Fruit Juice Reduces Oxidative Cell Damage in an Intervention Study with Patients on Hemodialysis

    Thomas M. Spormann;Franz W. Albert;Thomas Rath;Helmut Dietrich

  • Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity

    Karen M. Grant;Morag H. Dunion;Vanessa Yardley;Alexios-Leandros Skaltsounis

Frequent Co-Authors

Doris Marko
Doris Marko University of Vienna
Elke Richling
Elke Richling Technical University of Kaiserslautern
Stephen S. Hecht
Stephen S. Hecht University of Minnesota
Ivonne M.C.M. Rietjens
Ivonne M.C.M. Rietjens Wageningen University & Research
Laurent Meijer
Laurent Meijer Perha Pharmaceuticals
Samuel Monroe Cohen
Samuel Monroe Cohen University of Nebraska Medical Center
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Veronika Somoza
Veronika Somoza University of Vienna
Thomas Hofmann
Thomas Hofmann Technical University of Munich
Bernd Epe
Bernd Epe Johannes Gutenberg University of Mainz

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