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Biology and Biochemistry

D-Index
44
Citations
6694
World Ranking
19305
National Ranking
7888

Overview

Uta Griesenbach is affiliated with the National Institutes of Health in the United States and has a significant body of research focused primarily on gene therapy, genetics, and molecular biology. Their scholarly work intersects with medicine, especially pulmonary and respiratory medicine, reflecting a multidisciplinary approach to medical science and biomedical engineering.

The scientist's main fields of study include biochemistry, genetics, and molecular biology, with notable contributions in genetics and molecular biology specifically. Subfields of interest extend to pulmonary and respiratory medicine, electrical and electronic engineering, and infectious diseases.

Key research topics covered by Uta Griesenbach involve:

  • Virus-based gene therapy research
  • Energy harvesting in wireless networks
  • CRISPR and genetic engineering
  • Cystic fibrosis research advances
  • Viral gastroenteritis research and epidemiology
  • Neonatal respiratory health research
  • RNA interference and gene delivery

Uta Griesenbach has contributed multiple papers to various respected journals, with a concentration on respiratory and gene therapy areas. Some recent publications include:

  • "Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-in-Human Trial" (2024) in the American Journal of Respiratory and Critical Care Medicine
  • "Gene, RNA, and ASO-based therapeutic approaches in Cystic Fibrosis" (2023) in the Journal of Cystic Fibrosis
  • "Progress in Respiratory Gene Therapy" (2022) in Human Gene Therapy
  • "Gene Therapy for Respiratory Diseases: Progress and a Changing Context" (2020) in Human Gene Therapy
  • "Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis" (2025) in PLoS Pathogens

Their frequent coauthors include Eric W.F.W. Alton, Stephen C. Hyde, Deborah R. Gill, Jane C. Davies, and Gerry McLachlan. Collaborations with these researchers suggest ongoing work in gene therapy and respiratory disease research.

The primary venues for Uta Griesenbach's publications are:

  • Journal of Cystic Fibrosis
  • Human Gene Therapy
  • Cell and Gene Therapy Insights
  • American Journal of Respiratory and Critical Care Medicine
  • PLoS Pathogens

Best Publications

  • Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

    Eric W F W Alton;David K Armstrong;Deborah Ashby;Katie J Bayfield

  • CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

    Stephen C Hyde;Ian A Pringle;Syahril Abdullah;Syahril Abdullah;Anna E Lawton

  • Efficient gene transfer to airway epithelium using recombinant Sendai virus

    Yoshikazu Yonemitsu;Christopher Kitson;Stefano Ferrari;Raymond Farley

  • LUNG DISEASE IN MICE WITH CYSTIC FIBROSIS

    G Kent;R Iles;C E Bear;L J Huan

  • Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy.

    Uta Griesenbach;Eric W F W Alton

  • The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

    M Stern;NJ Caplen;JE Browning;U Griesenbach

  • Gene therapy progress and prospects: cystic fibrosis

    U Griesenbach;D M Geddes;E W F W Alton

  • Magnetic nanoparticles as gene delivery agents: enhanced transfection in the presence of oscillating magnet arrays.

    S C McBain;U Griesenbach;S Xenariou;A Keramane

  • Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes

    Katsuyuki Mitomo;Uta Griesenbach;Makoto Inoue;Lucinda Somerton

  • Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis.

    Eric W F W Alton;Jeffery M Beekman;A Christopher Boyd;June Brand;June Brand

  • Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

    Alex R Horsley;Jane C Davies;Jane C Davies;Robert D Gray;Kenneth A Macleod

  • Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.

    G McLachlan;H Davidson;E Holder;L A Davies

  • Progress and prospects: gene therapy clinical trials (part 2).

    U Griesenbach

  • Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy

    Uta Griesenbach;Makoto Inoue;Cuixiang Meng;Raymond Farley

  • Impaired Ability of Cftr Knockout Mice to Control Lung Infection with Pseudomonas aeruginosa

    Diane Gosselin;Mary M. Stevenson;Elizabeth A. Cowley;Uta Griesenbach

  • Cystic Fibrosis Gene Therapy in the UK and Elsewhere

    Uta Griesenbach;Kamila M. Pytel;Eric W.F.W. Alton

  • Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo.

    S Xenariou;U Griesenbach;S Ferrari;P Dean

  • Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy

    U. Griesenbach;A. Chonn;R. Cassady;V. Hannam

  • Emerging significance of plasmid DNA nuclear import in gene therapy

    Felix M. Munkonge;David A. Dean;Elizabeth Hillery;Uta Griesenbach

  • Specific inhibition of gene expression by small double stranded rnas

    Natasha J. Caplen;Richard A. Morgan;Andrew Fire;Susan Parrish

Frequent Co-Authors

Eric W.F.W. Alton
Eric W.F.W. Alton National Institutes of Health
Duncan M. Geddes
Duncan M. Geddes Imperial College London
David J. Porteous
David J. Porteous University of Edinburgh
Mamoru Hasegawa
Mamoru Hasegawa Kyushu University
Ronald K. Scheule
Ronald K. Scheule Sanofi (United States)
Seng H. Cheng
Seng H. Cheng Pfizer (United States)
Stefano Ferrari
Stefano Ferrari Veneto Eye Bank Foundation
Gordon D. Murray
Gordon D. Murray University of Edinburgh
Deborah Ashby
Deborah Ashby Imperial College London
James M. Wilson
James M. Wilson University of Pennsylvania

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