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D-Index & Metrics

Molecular Biology

D-Index
42
Citations
5869
World Ranking
3035
National Ranking
1439

Overview

Cyrus Vaziri is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research portfolio focuses primarily on molecular biology and cancer-related topics within the fields of biochemistry, genetics, molecular biology, and medicine.

The scientist's main research areas include:

  • DNA Repair Mechanisms
  • Cancer-related Molecular Pathways
  • Cancer Genomics and Diagnostics
  • Microtubule and Mitosis Dynamics
  • Genomics and Chromatin Dynamics
  • Glioma Diagnosis and Treatment
  • FOXO Transcription Factor Regulation

Vaziri has contributed extensively to subfields such as molecular biology, oncology, cancer research, cell biology, and immunology. Their frequent publication venues highlight areas of focus including cancer biology and molecular genetics.

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • NAR Cancer
  • Clinical Cancer Research
  • Neuro-Oncology

Selected recent papers authored or co-authored by Vaziri demonstrate their involvement in cancer research and DNA repair mechanisms:

  • "Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy," 2023, NAR Cancer
  • "Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy," 2020, JCI Insight
  • "Roles of Chk2/CHEK2 in guarding against environmentally induced DNA damage and replication-stress," 2020, Environmental and Molecular Mutagenesis
  • "Unravelling roles of error-prone DNA polymerases in shaping cancer genomes," 2021, Oncogene
  • "Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display," 2023, Journal of the American Chemical Society

Collaboration is an important aspect of Vaziri's research activities. Common co-authors include researchers with strong publication counts in related fields, indicating ongoing scientific partnerships.

  • Yanzhe Gao
  • Yang Yang
  • Di Wu
  • Gaith N. Droby
  • Jessica L. Bowser

Best Publications

  • MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.

    Frank Schembri;Sriram Sridhar;Catalina Perdomo;Adam M. Gustafson

  • A p53-Dependent Checkpoint Pathway Prevents Rereplication

    Cyrus Vaziri;Sandeep Saxena;Yesu Jeon;Yesu Jeon;Charles Lee

  • Rad18 Regulates DNA Polymerase κ and Is Required for Recovery from S-Phase Checkpoint-Mediated Arrest

    Xiaohui Bi;Laura R. Barkley;Damien M. Slater;Satoshi Tateishi

  • RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F.

    Gerald V. Denis;Cyrus Vaziri;Ning Guo;Douglas V. Faller

  • miR-129 regulates cell proliferation by downregulating Cdk6 expression

    Junjie Wu;Jun Qian;Chun Li;Letty Kwok

  • DNA polymerase κ is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint

    Xiaohui Bi;Damien M. Slater;Haruo Ohmori;Cyrus Vaziri

  • The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity.

    Edward F. Rocnik;Peijun Liu;Kaori Sato;Kenneth Walsh

  • Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals.

    Cyrus Vaziri;Ligaya Stice;Douglas V. Faller

  • The Chk1-mediated S-phase Checkpoint Targets Initiation Factor Cdc45 via a Cdc25A/Cdk2-independent Mechanism

    Peijun Liu;Laura R. Barkley;Tovah Day;Xiaohui Bi

  • A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks

    Michael Durando;Satoshi Tateishi;Cyrus Vaziri

  • Identification of a novel REV1-interacting motif necessary for DNA polymerase κ function

    Eiji Ohashi;Tomo Hanafusa;Keijiro Kamei;Ihnyoung Song

  • A Benzo[a]pyrene-induced Cell Cycle Checkpoint Resulting in p53-independent G1 Arrest in 3T3 Fibroblasts *

    Cyrus Vaziri;Douglas V. Faller

  • Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.

    Ning Guo;Douglas V. Faller;Cyrus Vaziri

  • The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

    Stacy A. Williams;Simonne Longerich;Patrick Sung;Cyrus Vaziri

  • Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication.

    Tovah A. Day;Komariah Palle;Laura R. Barkley;Naoko Kakusho

  • Role of Jade-1 in the Histone Acetyltransferase (HAT) HBO1 Complex

    Rebecca L. Foy;Ihn Young Song;Vipul C. Chitalia;Herbert T. Cohen

  • Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.

    Philip G. Wong;Michele A. Glozak;Thinh V. Cao;Cyrus Vaziri

  • Epstein-Barr Virus BPLF1 Deubiquitinates PCNA and Attenuates Polymerase η Recruitment to DNA Damage Sites

    Christopher B Whitehurst;Cyrus Vaziri;Julia A Shackelford;Joseph S Pagano

  • Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.

    Robert S. Weiss;Philip Leder;Cyrus Vaziri

  • Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway.

    Ihn Young Song;Komaraiah Palle;Aditi Gurkar;Satoshi Tateishi

Frequent Co-Authors

Douglas V. Faller
Douglas V. Faller Takeda (Japan)
Hisao Masai
Hisao Masai Tokyo Metropolitan Institute of Medical Science
Wellington V. Cardoso
Wellington V. Cardoso Columbia University
Avrum Spira
Avrum Spira Boston University
Grant S. Stewart
Grant S. Stewart University of Birmingham
Igor B. Rogozin
Igor B. Rogozin National Institutes of Health
Kimi Araki
Kimi Araki Kumamoto University
Marc E. Lenburg
Marc E. Lenburg Boston University
Takeshi Todo
Takeshi Todo Osaka University
Juan Li
Juan Li Sichuan University

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