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Biology and Biochemistry

D-Index
57
Citations
17136
World Ranking
13592
National Ranking
5765

Overview

Marc E. Lenburg is affiliated with Boston University in the United States. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology, focusing particularly on pulmonary and respiratory medicine as well as cancer research.

The scientist's work includes notable publications covering various aspects of lung diseases, molecular biology, and cancer. Recent papers include:

  • Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD, 2020, Scientific Reports
  • Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis, 2021, Cell Reports
  • Corrigendum to 'Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease' EBioMedicine 47 (2019) 446-456, 2020, EBioMedicine
  • The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF), 2021, EBioMedicine
  • Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas, 2022, Nature Communications

Collaborations have been an important aspect of their research, with frequent co-authors including Jennifer Beane, Avrum Spira, Sarah A. Mazzilli, Hanqiao Liu, and Gang Liu.

The venues where Marc E. Lenburg has published frequently include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • CHEST Journal
  • American Journal of Respiratory and Critical Care Medicine

Their book contribution includes a publication with the Centre National de la Recherche Scientifique titled European Socialists and the State in the Twentieth and Twenty-First Centuries (2020).

Main fields of study for this scientist encompass:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broad fields, specific subfields of emphasis include:

  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Cancer Research
  • Oncology
  • Infectious Diseases

The topics covered extensively in Marc E. Lenburg's research are:

  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • MicroRNA in disease regulation

Best Publications

  • The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

    Yi-Yi Zhu;Tamara Tchkonia;Tamar Pirtskhalava;Adam C Gower

  • Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain.

    Christopher Aiken;Jason Konner;Nathaniel R. Landau;Marc E. Lenburg;Marc E. Lenburg

  • A common genetic variant is associated with adult and childhood obesity.

    Alan Herbert;Norman P. Gerry;Matthew B. McQueen;Iris M. Heid

  • Dicer, Drosha, and outcomes in patients with ovarian cancer

    William M. Merritt;Yvonne G. Lin;Liz Y. Han;Aparna A. Kamat

  • Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

    Avrum Spira;Jennifer E Beane;Vishal Shah;Katrina Steiling

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.

    Frank Schembri;Sriram Sridhar;Catalina Perdomo;Adam M. Gustafson

  • Signaling phosphate starvation

    Marc E. Lenburg;Erin K. O'Shea

  • Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns.

    Tamara Tchkonia;Marc Lenburg;Thomas Thomou;Nino Giorgadze

  • Epithelial mesenchymal transition traits in human breast cancer cell lines.

    T. Blick;E. Widodo;E. Widodo;H. Hugo;M. Waltham

  • Chemotherapy response and recurrence-free survival in Neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

    Laura J. Esserman;Donald A. Berry;Maggie C. U. Cheang;Christina Yau

  • MYC Pathway Activation in Triple-Negative Breast Cancer Is Synthetic Lethal With CDK Inhibition

    Dai Horiuchi;Leonard Kusdra;Noelle E. Huskey;Sanjay Chandriani;Sanjay Chandriani

  • Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer

    Tony Blick;Honor Hugo;Edwin Widodo;Edwin Widodo;Mark Waltham

  • Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.

    Stephanie A. Christenson;Katrina Steiling;Maarten van den Berge;Kahkeshan Hijazi

  • Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data

    Marc E Lenburg;Louis S Liou;Norman P Gerry;Garrett M Frampton

  • Airway PI3K Pathway Activation Is an Early and Reversible Event in Lung Cancer Development

    Adam M. Gustafson;Raffaella Soldi;Christina Anderlind;Mary Beth Scholand

  • A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer

    Gerard A. Silvestri;Anil Vachani;Duncan Whitney;Michael Elashoff

  • Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease.

    Marc A. Sze;Pedro A. Dimitriu;Masaru Suzuki;Masaru Suzuki;John E. McDonough

  • A single-sample microarray normalization method to facilitate personalized-medicine workflows

    Stephen R. Piccolo;Ying Sun;Joshua D. Campbell;Marc E. Lenburg

  • Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

    Sriram Sridhar;Frank Schembri;Julie Zeskind;Vishal Shah

Frequent Co-Authors

Avrum Spira
Avrum Spira Boston University
Wim Timens
Wim Timens University Medical Center Groningen
Steven M. Dubinett
Steven M. Dubinett University of California, Los Angeles
Dirkje S. Postma
Dirkje S. Postma University Medical Center Groningen
Gang Liu
Gang Liu University of Alabama at Birmingham
James C. Hogg
James C. Hogg University of British Columbia
Stephen Lam
Stephen Lam University of British Columbia
George T. O'Connor
George T. O'Connor Boston University
Joel D. Cooper
Joel D. Cooper University of Pennsylvania
Joe W. Gray
Joe W. Gray Oregon Health & Science University

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