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Jan Michiels

Jan Michiels

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
15612
World Ranking
8668
National Ranking
150

Overview

Jan Michiels is affiliated with KU Leuven in Belgium and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a total of 111 publications. Their research spans several subfields including Molecular Biology, Genetics, Molecular Medicine, Ecology, and Plant Science.

The main topics covered in their work include:

  • Bacterial Genetics and Biotechnology
  • Antibiotic Resistance in Bacteria
  • Evolution and Genetic Dynamics
  • Microbial Metabolic Engineering and Bioproduction
  • Protein Structure and Dynamics
  • Bacteriophages and microbial interactions
  • Gut microbiota and health

Jan Michiels has frequently collaborated with several co-authors, notably:

  • Natalie Verstraeten (17 joint publications)
  • Bram Van den Bergh (13 joint publications)
  • Liselot Dewachter (13 joint publications)
  • Dorien Wilmaerts (11 joint publications)
  • Thomas Schalck (10 joint publications)

The scientist has published in various venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory) - 6 publications
  • Nature Communications - 5 publications
  • Microorganisms - 3 publications
  • Methods in molecular biology - 3 publications
  • Zenodo (CERN European Organization for Nuclear Research) - 3 publications

Among their recent papers, several are notable for their focus on bacterial adaptation, persistence, and antibiotic resistance mechanisms:

  • Bacteria under antibiotic attack: Different strategies for evolutionary adaptation, 2020, PLoS Pathogens
  • The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation, 2021, mBio
  • Ethanol exposure increases mutation rate through error-prone polymerases, 2020, Nature Communications
  • Protein Aggregation as a Bacterial Strategy to Survive Antibiotic Treatment, 2021, Frontiers in Molecular Biosciences
  • Ecology and evolution of antibiotic persistence, 2021, Trends in Microbiology

Jan Michiels's research broadly addresses the genetic and biochemical processes underlying bacterial responses to environmental stresses, including antibiotic pressure, with implications for understanding evolutionary adaptation mechanisms and persistence phenotypes.

Best Publications

  • Definitions and guidelines for research on antibiotic persistence

    Naomi N.Q. Balaban;Sophie Helaine;Kim Lewis;Martin Ackermann;Martin Ackermann

  • Quorum sensing and swarming migration in bacteria

    R. S. Daniels;Jos Vanderleyden;Jan Jacques Michiels

  • Living on a surface: swarming and biofilm formation

    Natalie Verstraeten;Kristien Braeken;Bachaspatimayum Debkumari;Maarten Fauvart

  • Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies.

    Maarten Fauvart;Valerie N. De Groote;Jan Michiels

  • Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates

    Etthel Martha Windels;Etthel Martha Windels;Joran Elie Michiels;Joran Elie Michiels;Maarten Fauvart;Tom Wenseleers

  • Formation, physiology, ecology, evolution and clinical importance of bacterial persisters.

    Bram Van den Bergh;Maarten Fauvart;Jan Michiels

  • Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance

    Natalie Verstraeten;Wouter Joris Knapen;Cyrielle Ines Kint;Veerle Liebens

  • Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

    Bram Van den Bergh;Joran E. Michiels;Tom Wenseleers;Etthel M. Windels

  • New horizons for (p)ppGpp in bacterial and plant physiology

    Kristien Braeken;Martine Moris;Ruth Daniels;Jozef Vanderleyden

  • Physiological and genetic analysis of root responsiveness to auxin-producing plant growth-promoting bacteria in common bean (Phaseolus vulgaris L.)

    Roseline Remans;Steve Beebe;Matthew Blair;German Manrique

  • The functions of Ca2+ in bacteria: a role for EF-hand proteins?

    Jan Michiels;Chuanwu Xi;Jan Verhaert;Jozef Vanderleyden

  • Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa

    Yves Briers;Maarten Walmagh;Barbara Grymonprez;Manfred Biebl

  • The Universally Conserved Prokaryotic GTPases

    Natalie Verstraeten;Maarten Fauvart;Wim Versées;Jan Michiels

  • The fungal aroma gene ATF1 promotes dispersal of yeast cells through insect vectors.

    Joaquin F. Christiaens;Luis M. Franco;Tanne L. Cools;Luc De Meester

  • Quorum signal molecules as biosurfactants affecting swarming in Rhizobium etli

    Ruth Daniels;Sven Reynaert;Hans Hoekstra;Christel Verreth

  • Phaseolus vulgaris is a non‐selective host for nodulation

    Jan Michiels;Bruno Dombrecht;Nicolas Vermeiren;Chuanwu Xi

  • Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics

    Valerie Defraine;Maarten Fauvart;Jan Michiels;Jan Michiels

  • Identification of different emitting species in the red fluorescent protein DsRed by means of ensemble and single-molecule spectroscopy

    Mircea Cotlet;Johan Hofkens;Satoshi Habuchi;Gunter Dirix

  • Rhizobial secreted proteins as determinants of host specificity in the rhizobium-legume symbiosis.

    Maarten Fauvart;Jan Michiels

  • Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance.

    Liselot Dewachter;Maarten Fauvart;Jan Michiels

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