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Masatoshi Fujita

Masatoshi Fujita

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8496
World Ranking
18380
National Ranking
1322

Overview

Masatoshi Fujita is affiliated with Kyushu University in Japan and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans various subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, Physiology, and Aging. The scientist's research topics include DNA Repair Mechanisms, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering, Telomeres, Telomerase, and Senescence, Genetics, Aging, and Longevity in Model Organisms, Microtubule and Mitosis Dynamics, and Single-cell and Spatial Transcriptomics.

Their recent papers cover significant developments in DNA replication stress and damage responses, among other subjects. These include:

  • TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress, 2021, Nucleic Acids Research
  • DNA damage responses that enhance resilience to replication stress, 2021, Cellular and Molecular Life Sciences
  • SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions, 2020, The Journal of Cell Biology
  • A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia, 2024, International Journal of Hematology
  • Discriminative feature of cells characterizes cell populations of interest by a small subset of genes, 2021, PLoS Computational Biology

Masatoshi Fujita frequently collaborates with a number of co-authors including Kazumasa Yoshida, Nozomi Sugimoto, Mitsunori Higa, Takeru Fujii, and Kazumitsu Maehara.

Their studies have appeared in several scientific venues, notably:

  • The Journal of Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Cellular and Molecular Life Sciences
  • The Journal of Cell Biology

Best Publications

  • Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

    Tohru Kiyono;Atsuro Hiraiwa;Masatoshi Fujita;Yasuyuki Hayashi

  • Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

    Hidemasa Goto;Yasuko Tomono;Kozo Ajiro;Hidetaka Kosako

  • The World Health Organization classification of malignant lymphomas in Japan: Incidence of recently recognized entities

    M. Fujita;K. Yamashiro;R. Ichinohasama;N. Nakamura

  • Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

    Hideo Nishitani;Nozomi Sugimoto;Vassilis Roukos;Yohsuke Nakanishi

  • Latent and lytic Epstein-Barr virus replication strategies.

    Tatsuya Tsurumi;Masatoshi Fujita;Ayumi Kudoh

  • Regulation of Notch1 gene expression by p53 in epithelial cells.

    Takashi Yugawa;Keisuke Handa;Mako Narisawa-Saito;Shin Ichi Ohno

  • Cdt1 Phosphorylation by Cyclin A-dependent Kinases Negatively Regulates Its Function without Affecting Geminin Binding

    Nozomi Sugimoto;Yasutoshi Tatsumi;Tatsuya Tsurumi;Akio Matsukage

  • Gene Therapy for Hepatoma Cells Using a Retrovirus Vector Carrying Herpes Simplex Virus Thymidine Kinase Gene under the Control of Human α-Fetoprotein Gene Promoter

    Akio Ido;Keisuke Nakata;Yuji Kato;Kazuhiko Nakao

  • Epstein-Barr Virus Lytic Replication Elicits ATM Checkpoint Signal Transduction While Providing an S-phase-like Cellular Environment *

    Ayumi Kudoh;Masatoshi Fujita;Lumin Zhang;Noriko Shirata

  • Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.

    Noriko Shirata;Ayumi Kudoh;Tohru Daikoku;Yasutoshi Tatsumi

  • Cell Cycle Regulation of Human CDC6 Protein INTRACELLULAR LOCALIZATION, INTERACTION WITH THE HUMAN MCM COMPLEX, AND CDC2 KINASE-MEDIATED HYPERPHOSPHORYLATION

    Masatoshi Fujita;Chieko Yamada;Hidemasa Goto;Naoaki Yokoyama

  • Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.

    Masatoshi Fujita

  • Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: Cleavage furrow-specific phosphorylation of intermediate filaments

    Hidetaka Kosako;Hidemasa Goto;Maki Yanagida;Kaori Matsuzawa

  • Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.

    Yasutoshi Tatsumi;Nozomi Sugimoto;Takashi Yugawa;Mako Narisawa-Saito

  • Rapid Determination of Epstein-Barr Virus–Specific CD8+T-Cell Frequencies by Flow Cytometry

    Kiyotaka Kuzushima;Yo Hoshino;Ken Fujii;Naoaki Yokoyama

  • Reactivation of Lytic Replication from B Cells Latently Infected with Epstein-Barr Virus Occurs with High S-Phase Cyclin-Dependent Kinase Activity while Inhibiting Cellular DNA Replication

    Ayumi Kudoh;Masatoshi Fujita;Tohru Kiyono;Kiyotaka Kuzushima

  • Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.

    Rumi Sasaki;Mako Narisawa-Saito;Takashi Yugawa;Masatoshi Fujita

  • The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle

    Satoshi Ohta;Yasutoshi Tatsumi;Masatoshi Fujita;Toshiki Tsurimoto

  • Cdk2-dependent and -independent pathways in E2F-mediated S phase induction.

    Yukinobu Arata;Masatoshi Fujita;Kiyoshi Ohtani;Sho Kijima

  • Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

    Kei Haga;Shin Ichi Ohno;Takashi Yugawa;Mako Narisawa-Saito

Frequent Co-Authors

Tohru Kiyono
Tohru Kiyono National Cancer Research Institute, UK
Tatsuya Tsurumi
Tatsuya Tsurumi Nagoya City University
Yasuyuki Ohkawa
Yasuyuki Ohkawa Kyushu University
Yukihiro Nishiyama
Yukihiro Nishiyama Nagoya University
Naoaki Yokoyama
Naoaki Yokoyama Obihiro University of Agriculture and Veterinary Medicine
Chikashi Obuse
Chikashi Obuse Osaka University
Masaki Inagaki
Masaki Inagaki Mie University
Hidetaka Kosako
Hidetaka Kosako University of Tokushima
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Yoshiyuki Mizushina
Yoshiyuki Mizushina Shinshu University

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