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D-Index & Metrics

Molecular Biology

D-Index
74
Citations
18319
World Ranking
1235
National Ranking
95

Overview

Tohru Kiyono is affiliated with the National Cancer Research Institute, UK, located in the United Kingdom. Their research spans several interconnected fields, primarily focusing on medicine, biochemistry, genetics, and molecular biology. Within these broad domains, Kiyono's work extends notably into molecular biology, surgery, genetics, oncology, and reproductive medicine.

The scientist's research is closely associated with multiple main topics, reflecting a diverse range of interests and expertise. These topics include virus-based gene therapy research, pluripotent stem cells research, pancreatic function and diabetes, liver physiology and pathology, CRISPR and genetic engineering, endometriosis research and treatment, and ovarian cancer diagnosis and treatment.

Throughout their career, Kiyono has contributed to various articles appearing in prominent publication venues. Frequent venues for their work include bioRxiv (Cold Spring Harbor Laboratory), PLoS ONE, Cancers, Stem Cell Research & Therapy, and Scientific Reports.

Their recent research publications feature the following papers:

  • Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts (2023), published in Science Translational Medicine
  • YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma (2020), published in Science Advances
  • Striated myocyte structural integrity: Automated analysis of sarcomeric z-discs (2020), published in PLoS Computational Biology
  • Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder (2021), published in Stem Cell Research & Therapy
  • Identifying high-grade serous ovarian carcinoma-specific extracellular vesicles by polyketone-coated nanowires (2023), published in Science Advances

Kiyono has collaborated extensively with several coauthors in their research endeavors. Frequent coauthors include Tomokazu Fukuda, Akihiro Umezawa, Ai Orimoto, Eriko Sugano, and Hiroshi Tomita.

Best Publications

  • Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells

    Tohru Kiyono;Scott A. Foster;Jenn I. Koop;James K. McDougall

  • Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

    Tohru Kiyono;Atsuro Hiraiwa;Masatoshi Fujita;Yasuyuki Hayashi

  • HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

    Matthew A. Deardorff;Masashige Bando;Ryuichiro Nakato;Erwan Watrin

  • Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins.

    Mako Narisawa-Saito;Tohru Kiyono

  • Novel Cardiac Precursor‐Like Cells from Human Menstrual Blood‐Derived Mesenchymal Cells

    Naoko Hida;Naoko Hida;Nobuhiro Nishiyama;Shunichiro Miyoshi;Shinichiro Kira

  • Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells.

    Takeshi Okamoto;Tomoki Aoyama;Tomitaka Nakayama;Takeharu Nakamata

  • Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex

    Lindy Gewin;Hadley Myers;Tohru Kiyono;Denise A. Galloway

  • Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins

    Takashi Yugawa;Tohru Kiyono

  • Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

    Akira Yokoi;Yusuke Yoshioka;Yusuke Yamamoto;Mitsuya Ishikawa

  • Regulation of Notch1 gene expression by p53 in epithelial cells.

    Takashi Yugawa;Keisuke Handa;Mako Narisawa-Saito;Shin Ichi Ohno

  • Filament Formation of MSF-A, a Mammalian Septin, in Human Mammary Epithelial Cells Depends on Interactions with Microtubules

    Koh ichi Nagata;Aie Kawajiri;Seiya Matsui;Mihoko Takagishi

  • Cdt1 Phosphorylation by Cyclin A-dependent Kinases Negatively Regulates Its Function without Affecting Geminin Binding

    Nozomi Sugimoto;Yasutoshi Tatsumi;Tatsuya Tsurumi;Akio Matsukage

  • Menstrual blood-derived cells confer human dystrophin expression in the murine model of Duchenne muscular dystrophy via cell fusion and myogenic transdifferentiation.

    Chang-Hao Cui;Taro Uyama;Kenji Miyado;Masanori Terai

  • Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

    Hiroyasu Inada;Ichiro Izawa;Miwako Nishizawa;Eriko Fujita

  • Successful immortalization of endometrial glandular cells with normal structural and functional characteristics.

    Satoru Kyo;Mitsuhiro Nakamura;Tohru Kiyono;Yoshiko Maida

  • Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.

    Hidemasa Goto;Tohru Kiyono;Yasuko Tomono;Aie Kawajiri

  • NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

    Tatsuhiro Shibata;Akiko Kokubu;Shigeru Saito;Mako Narisawa-Saito

  • Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.

    Noriko Shirata;Ayumi Kudoh;Tohru Daikoku;Yasutoshi Tatsumi

  • Cementum matrix formation in vivo by cultured dental follicle cells

    K. Handa;Masahiro Saito;M. Yamauchi;T. Kiyono

  • Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma.

    Shigeki Sekine;Tohru Kiyono;Eijitsu Ryo;Reiko Ogawa

Frequent Co-Authors

Masatoshi Fujita
Masatoshi Fujita Kyushu University
Akihiro Umezawa
Akihiro Umezawa National Center For Child Health and Development
Masaki Inagaki
Masaki Inagaki Mie University
Hidemasa Goto
Hidemasa Goto Mie University
Tatsuya Tsurumi
Tatsuya Tsurumi Nagoya City University
Fumitaka Kikkawa
Fumitaka Kikkawa Nagoya University
Kiyotaka Nakagawa
Kiyotaka Nakagawa Tohoku University
Masahiko Kuroda
Masahiko Kuroda Tokyo Medical University
Hiroshi Nishina
Hiroshi Nishina Tokyo Medical and Dental University
Jun Yokota
Jun Yokota National Cancer Centre

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