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Microbiology

D-Index
58
Citations
17694
World Ranking
3368
National Ranking
296

Overview

John Doorbar is a researcher affiliated with the University of Cambridge in the United Kingdom. Their expertise spans multiple fields within biomedical science, with a substantial focus on medicine and biochemistry, genetics, and molecular biology. Doorbar's work is prominently situated in areas such as epidemiology, molecular biology, surgery, cancer research, and immunology.

The research topics that Doorbar has explored include cervical cancer and HPV research, genital health and disease, cancer-related molecular mechanisms, hepatitis B virus studies, reproductive tract infections, epigenetics and DNA methylation, and the application of molecular biology techniques.

Their publication record features notable recent papers that reflect a focus on viral studies, immunology, and cancer-related research. These include:

  • "Discovery of several thousand highly diverse circular DNA viruses," published in 2020 in eLife
  • "Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy," published in 2021 in Cell
  • "Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI," published in 2020 in Oral Oncology
  • "Prophylactic HPV vaccines in patients with HPV-associated diseases and cancer," published in 2023 in Vaccine
  • "The early detection of cervical cancer. The current and changing landscape of cervical disease detection," published in 2020 in Cytopathology

Doorbar frequently collaborates with several researchers, with whom they have coauthored multiple works. These frequent coauthors include Heather Griffin, Nagayasu Egawa, Ke Zheng, Aslam Shiraz, and Marta del Pino.

Their research has been published across various scientific journals, underscoring a consistent engagement with specialized venues relevant to their areas of study. Key publication venues include Tumour Virus Research, Viruses, Vaccine, EBioMedicine, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • The biology and life-cycle of human papillomaviruses.

    John Doorbar;Wim Quint;Lawrence Banks;Ignacio G. Bravo

  • Molecular biology of human papillomavirus infection and cervical cancer.

    John Doorbar

  • The papillomavirus life cycle.

    John Doorbar

  • Human papillomavirus molecular biology and disease association

    John Doorbar;Nagayasu Egawa;Heather Griffin;Christian Kranjec

  • Carcinogenic human papillomavirus infection.

    Mark Schiffman;John Doorbar;Nicolas Wentzensen;Silvia de Sanjosé

  • Comprehensive control of human papillomavirus infections and related diseases.

    F. Xavier Bosch;Thomas R. Broker;David Forman;Anna Barbara Moscicki

  • Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia

    Nagayasu Egawa;Kiyofumi Egawa;Heather Griffin;John Doorbar

  • Specific interaction between HPV-16 E1-E4 and cytokeratins results in collapse of the epithelial cell intermediate filament network.

    J. Doorbar;S. Ely;J. Sterling;C. McLean

  • Organization of Human Papillomavirus Productive Cycle during Neoplastic Progression Provides a Basis for Selection of Diagnostic Markers

    Kate Middleton;Woei Peh;Shirley Southern;Heather Griffin

  • The E4 protein; structure, function and patterns of expression.

    John Doorbar

  • The low-risk papillomaviruses

    Nagayasu Egawa;John Doorbar

  • Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line

    J. Doorbar;A. Parton;K. Hartley;L. Banks

  • Identification of the human papilloma virus-1a E4 gene products.

    J. Doorbar;D. Campbell;R. J. A. Grand;P. H. Gallimore

  • Life Cycle Heterogeneity in Animal Models of Human Papillomavirus-Associated Disease

    Woei Ling Peh;Kate Middleton;Neil Christensen;Philip Nicholls

  • One virus, one lesion--individual components of CIN lesions contain a specific HPV type.

    Wim Quint;David Jenkins;Anco Molijn;Linda Struijk

  • Characterization of Events during the Late Stages of HPV16 Infection in Vivo Using High-Affinity Synthetic Fabs to E4

    John Doorbar;Charmaine Foo;Nick Coleman;Liz Medcalf

  • Persistence of viral DNA in the epithelial basal layer suggests a model for papillomavirus latency following immune regression.

    Gareth Adam Maglennon;Pauline McIntosh;John Doorbar

  • Papillomavirus life cycle organization and biomarker selection.

    John Doorbar

  • G2/M cell cycle arrest in the life cycle of viruses

    Clare Davy;John Doorbar

  • Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin.

    Kate Matthews;Cheng Mee Leong;Lindsay Baxter;Emma Inglis

  • Identification of proteins encoded by the L1 and L2 open reading frames of human papillomavirus 1a.

    J Doorbar;P H Gallimore

Frequent Co-Authors

Wim Quint
Wim Quint Erasmus University Rotterdam
Arvind Varsani
Arvind Varsani Arizona State University
Lawrence Banks
Lawrence Banks International Centre for Genetic Engineering and Biotechnology
Chris J.L.M. Meijer
Chris J.L.M. Meijer Vrije Universiteit Amsterdam
Nicholas Coleman
Nicholas Coleman University of Cambridge
Margaret Stanley
Margaret Stanley University of Cambridge
Matthew B. Sullivan
Matthew B. Sullivan The Ohio State University
Barbara Rehermann
Barbara Rehermann National Institute of Diabetes and Digestive and Kidney Diseases
Juan C. Troncoso
Juan C. Troncoso Johns Hopkins University School of Medicine
David H. McDermott
David H. McDermott National Institutes of Health

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