World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
47
Citations
9832
World Ranking
4498
National Ranking
2034

Overview

David H. McDermott is affiliated with the National Institutes of Health in the United States. Their research spans multiple areas within medicine, particularly focusing on immunology and oncology. The bulk of their academic contributions address topics such as cancer immunotherapy and biomarkers, renal cell carcinoma treatment, and immunodeficiency and autoimmune disorders.

The scientist has produced significant work related to chemokine receptors and signaling, immunotherapy and immune responses, immune cell function and interaction, and T-cell and B-cell immunology. These thematic areas illustrate a strong focus on understanding immune mechanisms and their applications to disease treatment, especially in cancer and immune-related conditions.

David H. McDermott has collaborated frequently with several researchers in their field. These frequent co-authors include:

  • Philip M. Murphy
  • Shamik Majumdar
  • Toni K. Choueiri
  • Karl Balabanian
  • Amélie Bonaud

Their research has been published in various scientific journals, with multiple publications appearing in the following venues:

  • Journal of Clinical Oncology
  • Blood
  • Journal of Allergy and Clinical Immunology
  • Journal of Clinical Immunology
  • The Journal of Immunology

Selected recent papers authored or co-authored by David H. McDermott include:

  • Perioperative nivolumab versus observation in patients with renal cell carcinoma undergoing nephrectomy (PROSPER ECOG-ACRIN EA8143): an open-label, randomised, phase 3 study, 2024, The Lancet Oncology
  • Antibody responses to the SARS-CoV-2 vaccine in individuals with various inborn errors of immunity, 2021, Journal of Allergy and Clinical Immunology
  • Discovery of several thousand highly diverse circular DNA viruses, 2020, eLife
  • Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1, 2020, Science Immunology
  • Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations, 2022, Journal of Allergy and Clinical Immunology

Their scholarly output covers major fields of study including medicine and immunology and microbiology. Among subfields, the scientist's work spans immunology, oncology, pulmonary and respiratory medicine, molecular biology, and hematology.

Best Publications

  • CCR5 deficiency increases risk of symptomatic West Nile virus infection.

    William G. Glass;David H. McDermott;Jean K. Lim;Sudkamon Lekhong

  • CCR5 promoter polymorphism and HIV-1 disease progression

    David H McDermott;Peter A Zimmerman;Peter A Zimmerman;Florence Guignard;Cynthia A Kleeberger

  • Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.

    Ji-Liang Gao;D. B. Kuhns;H. L. Tiffany;D. Mcdermott

  • Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease

    Didier Moatti;Sophie Faure;Frédéric Fumeron;Mohamed El Walid Amara

  • Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1.

    Sophie Faure;Laurence Meyer;Dominique Costagliola;Céline Vaneensberghe

  • Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans.

    David H. McDermott;Alan M. Fong;Qiong Yang;Joan M. Sechler

  • CCL2 Polymorphisms Are Associated With Serum Monocyte Chemoattractant Protein-1 Levels and Myocardial Infarction in the Framingham Heart Study

    David H. McDermott;Qiong Yang;Sekar Kathiresan;L. Adrienne Cupples

  • Association Between Polymorphism in the Chemokine Receptor CX3CR1 and Coronary Vascular Endothelial Dysfunction and Atherosclerosis

    David H. McDermott;Julian P.J. Halcox;William H. Schenke;Myron A. Waclawiw

  • A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family.

    P M Murphy;T Ozçelik;R T Kenney;H L Tiffany

  • Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man

    Jean K. Lim;Andrea Lisco;David H. McDermott;Linda Huynh

  • Human T and Natural Killer Cells Possess a Functional Renin-Angiotensin System: Further Mechanisms of Angiotensin II–Induced Inflammation

    Mollie Jurewicz;David H. McDermott;Joan M. Sechler;Kathryn Tinckam

  • Chemokine RANTES promoter polymorphism affects risk of both HIV infection and disease progression in the Multicenter AIDS Cohort study

    David H. McDermott;Matthew J. Beecroft;Cynthia A. Kleeberger;Fadwa M. Al-Sharif

  • Genetic Deficiency of Chemokine Receptor CCR5 Is a Strong Risk Factor for Symptomatic West Nile Virus Infection: A Meta-Analysis of 4 Cohorts in the US Epidemic

    Jean K. Lim;Christine Y. Louie;Carol Glaser;Cynthia Jean

  • Chromothriptic Cure of WHIM Syndrome

    David H. McDermott;Ji-Liang Gao;Qian Liu;Marie Siwicki

  • Chemokine Receptor Polymorphism and Risk of Acute Rejection in Human Renal Transplantation

    Reza Abdi;Tran Thi Bich Huong;Alfredo Sahagun-Ruiz;Philip M. Murphy

  • Discovery of several thousand highly diverse circular DNA viruses.

    Michael J. Tisza;Diana V. Pastrana;Nicole L. Welch;Brittany Stewart

  • A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor.

    David H. McDermott;Qian Liu;Daniel Velez;Lizbeeth Lopez

  • Complete Genome Sequence of a Tenth Human Polyomavirus

    Christopher B. Buck;Giao Q. Phan;Manish T. Raiji;Philip M. Murphy

  • Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C

    Kittichai Promrat;David H. McDermott;Carlos M. Gonzalez;David E. Kleiner

  • The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome.

    David H. McDermott;Qian Liu;Jean Ulrick;Nana Kwatemaa

Frequent Co-Authors

Philip M. Murphy
Philip M. Murphy National Institutes of Health
Ji-Liang Gao
Ji-Liang Gao National Institute of Allergy and Infectious Diseases
Harry L. Malech
Harry L. Malech National Institutes of Health
Douglas B. Kuhns
Douglas B. Kuhns National Institutes of Health
Christopher B. Buck
Christopher B. Buck National Institutes of Health
Arvind Varsani
Arvind Varsani Arizona State University
Stefania Pittaluga
Stefania Pittaluga National Institutes of Health
Christophe Combadière
Christophe Combadière Sorbonne University
Stephen F. Porcella
Stephen F. Porcella National Institutes of Health
Alison A. McBride
Alison A. McBride National Institutes of Health

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Related Online Degrees & Career Pathways

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