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D-Index & Metrics

Microbiology

D-Index
53
Citations
7642
World Ranking
4149
National Ranking
369

Overview

James E. Pease is affiliated with Imperial College London in the United Kingdom. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology.

The scientist has focused on subfields including Immunology, Public Health, Environmental and Occupational Health, Molecular Biology, Oncology, and Infectious Diseases. Their work addresses several key topics such as Chemokine receptors and signaling, Streptococcal Infections and Treatments, Neonatal and Maternal Infections, Immunotherapy and Immune Responses, Glycosylation and Glycoproteins Research, T-cell and B-cell Immunology, and interferon and immune responses.

James E. Pease has published multiple papers, including these recent works:

  • Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy, 2020, Journal of Clinical Medicine
  • A degradatory fate for CCR4 suggests a primary role in Th2 inflammation, 2020, Journal of Leukocyte Biology
  • Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes, 2020, Computational and Structural Biotechnology Journal
  • CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling, 2023, Frontiers in Immunology
  • What defines a chemokine? - The curious case of CXCL17, 2023, Cytokine

The scientist frequently collaborates with other researchers, including:

  • Sean Patrick Giblin
  • Shiranee Sriskandan
  • Sophie McKenna
  • Max Pearson
  • Stephen Matthews

James E. Pease has published extensively in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytokine
  • PLoS ONE
  • Scientific Reports
  • Journal of Clinical Medicine

Best Publications

  • The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy.

    James E. Pease;Ian Sabroe

  • Identification of CCR8: A human monocyte and thymus receptor for the CC chemokine I-309

    H. Lee Tiffany;Laura L. Lautens;Ji Liang Gao;James Pease

  • A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3 POTENT INHIBITION OF EOSINOPHIL FUNCTION AND CCR3-MEDIATED HIV-1 ENTRY

    I Sabroe;MJ Peck;BJ Van Keulen;A Jorritsma

  • IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

    Katrina Blazek;Hayley L. Eames;Miriam Weiss;Adam J. Byrne

  • Differential Regulation of Eosinophil Chemokine Signaling Via CCR3 and Non-CCR3 Pathways

    Ian Sabroe;Adele Hartnell;Louise A. Jopling;Sandra Bel

  • Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy.

    Leila Motedayen Aval;James E. Pease;Rohini Sharma;David J. Pinato

  • CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11.

    Georgina Xanthou;Cécile Emmanuelle Duchesnes;Timothy John Williams;James Edward Pease

  • Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3.

    Byung S. Youn;Shang M. Zhang;Eun K. Lee;Doo H. Park

  • The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1alpha and eotaxin binding, respectively, but a second domain is essential for efficient receptor activation.

    James E. Pease;James E. Pease;Juan Wang;Paul D. Ponath;Philip M. Murphy

  • Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function

    Laura Denney;Adam J. Byrne;Thomas J. Shea;James S. Buckley

  • The Chemokine Receptor CXCR3 Is Degraded following Internalization and Is Replenished at the Cell Surface by De Novo Synthesis of Receptor

    Andrea Meiser;Anja Mueller;Emma L. Wise;Ellen M. McDonagh

  • IRF5 controls both acute and chronic inflammation

    Miriam Weiss;Adam J. Byrne;Adam J. Byrne;Katrina Blazek;David G. Saliba

  • The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo

    Sarah J. Collington;Jenny Hallgren;James E. Pease;Tatiana G. Jones

  • Eotaxin and asthma

    James E Pease;Timothy J Williams

  • Chemokines and their receptors in allergic disease

    James Edward Pease;Timothy John Williams

  • 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils.

    Eva Böhm;Gunter J. Sturm;Iris Weiglhofer;Hilary Sandig

  • CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3

    Anja Mueller;Andrea Meiser;Ellen M. McDonagh;James M. Fox

  • Chemokine receptor antagonists: Part 1.

    James E Pease;Richard Horuk

  • Asthma, allergy and chemokines.

    James E Pease

  • Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi-step model of ligand binding and receptor activation.

    Georgina Xanthou;Timothy J Williams;James E Pease

  • The CXC Chemokine MIG/CXCL9 Is Important in Innate Immunity against Streptococcus pyogenes

    Arne Egesten;Mette Eliasson;Helena M. Johansson;Anders I. Olin

Frequent Co-Authors

Timothy J. Williams
Timothy J. Williams National Institutes of Health
Ian Sabroe
Ian Sabroe University of Sheffield
Philip M. Murphy
Philip M. Murphy National Institutes of Health
Peter N. Monk
Peter N. Monk University of Sheffield
Clare M. Lloyd
Clare M. Lloyd Imperial College London
Richard Horuk
Richard Horuk University of California, Davis
Geoffrey L. Smith
Geoffrey L. Smith University of Oxford
Shiranee Sriskandan
Shiranee Sriskandan Imperial College London
Matthias Mörgelin
Matthias Mörgelin Lund University
Dennis R. Burton
Dennis R. Burton Scripps Research Institute

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