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Microbiology

D-Index
58
Citations
9322
World Ranking
3500
National Ranking
307

Overview

Shiranee Sriskandan is affiliated with Imperial College London in the United Kingdom. Their research spans multiple fields including Medicine with a focus on Infectious Diseases, Public Health, Environmental and Occupational Health, Epidemiology, Molecular Biology, and Molecular Medicine. The volume of publications reflects a broad engagement with topics central to clinical and molecular aspects of infectious diseases.

The scientist's research covers several main topics, including:

  • Streptococcal Infections and Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Neonatal and Maternal Infections
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Antibiotic Resistance in Bacteria
  • Bacterial Identification and Susceptibility Testing

Some of their most cited recent papers illustrate involvement in COVID-19 research during the pandemic. These include:

  • "Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study," 2021, published in The Lancet Microbe
  • "Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19," 2021, published in Science Immunology
  • "Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study," 2021, published in The Lancet Respiratory Medicine
  • "Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK," 2021, published in The Lancet Respiratory Medicine
  • "Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study," 2021, published in The Lancet

Frequent co-authors highlight collaborations in infectious disease and clinical research. These include:

  • Peter Openshaw
  • Malcolm G. Semple
  • J. Kenneth Baillie
  • Annemarie B Docherty
  • Mahdad Noursadeghi

Their work is regularly published in key scientific venues. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Lancet Microbe
  • Nature Communications
  • Microbial Genomics
  • Clinical Infectious Diseases

Best Publications

  • Genetic mechanisms of critical illness in Covid-19.

    E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  • The immunology of sepsis.

    S Sriskandan;DM Altmann

  • Mammalian Toll-like receptors: to immunity and beyond.

    P. A. Hopkins;S. Sriskandan

  • Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.

    Clark D Russell;Cameron J Fairfield;Thomas M Drake;Lance Turtle

  • GRAM-POSITIVE SEPSIS: Mechanisms and Differences from Gram-Negative Sepsis

    Shiranee Sriskandan;Jonathan Cohen

  • Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.

    Ryan S Thwaites;Ashley Sanchez Sevilla Uruchurtu;Matthew K Siggins;Felicity Liew

  • Specific C-Terminal Cleavage and Inactivation of Interleukin-8 by Invasive Disease Isolates of Streptococcus pyogenes

    Robert J. Edwards;Graham W. Taylor;Melissa Ferguson;Stephen Murray

  • Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.

    Nicola N Lynskey;Elita Jauneikaite;Elita Jauneikaite;Ho Kwong Li;Xiangyun Zhi

  • The IL-8 Protease SpyCEP/ScpC of Group A Streptococcus Promotes Resistance to Neutrophil Killing

    Annelies S. Zinkernagel;Anjuli M. Timmer;Morgan A. Pence;Jeffrey B. Locke

  • Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.

    Tom Parks;Clare Wilson;Nigel Curtis;Anna Norrby-Teglund

  • Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK.

    Chloe I Bloom;Thomas M Drake;Annemarie B Docherty;Brian J Lipworth

  • Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study.

    Thomas M Drake;Aya M Riad;Cameron J Fairfield;Conor Egan

  • The Mechanism of Superantigen-Mediated Toxic Shock: Not a Simple Th1 Cytokine Storm

    Lee Faulkner;Anneli Cooper;Cristina Fantino;Daniel M. Altmann

  • Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom

    Claire E. Turner;James Abbott;Theresa Lamagni;Matthew T. G. Holden;Matthew T. G. Holden

  • Superantigens and streptococcal toxic shock syndrome

    Thomas Proft;Shiranee Sriskandan;Lily Yang;John D. Fraser

  • Necrotising soft-tissue infections.

    Unknown

  • HLA Class II Polymorphisms Determine Responses to Bacterial Superantigens

    Martin Llewelyn;Shiranee Sriskandan;Mark Peakman;David R. Ambrozak

  • Detection of circulating bacterial superantigen and lymphotoxin-a in patients with streptococcal toxic-shock syndrome

    Shiranee Sriskandan;David Moyes;Jonathan Cohen

  • Emerging Role of the Interleukin-8 Cleaving Enzyme SpyCEP in Clinical Streptococcus pyogenes Infection

    Claire E. Turner;Prathiba Kurupati;Michael D. Jones;Robert J. Edwards

  • SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

    Unknown

  • Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation

    Shiranee Sriskandan;Melissa Ferguson;Victoria Elliot;Lee Faulkner

  • Invasive disease and toxic shock due to zoonotic Streptococcus suis: An emerging infection in the East?

    Shiranee Sriskandan;Josh D Slater

  • Pro-Inflammatory Mechanisms in Sepsis

    Deborah L.W. Chong;Shiranee Sriskandan

Frequent Co-Authors

Daniel M. Altmann
Daniel M. Altmann Imperial College London
Matthew T. G. Holden
Matthew T. G. Holden University of St Andrews
Androulla Efstratiou
Androulla Efstratiou Public Health England
Alison Holmes
Alison Holmes Imperial College London
David L. Moyes
David L. Moyes Imperial College London
Andrew J. Pollard
Andrew J. Pollard University of Oxford
Jonathan Cohen
Jonathan Cohen The University of Texas Southwestern Medical Center
Jane A. Mitchell
Jane A. Mitchell National Institutes of Health
Mahdad Noursadeghi
Mahdad Noursadeghi University College London
Thomas Krausz
Thomas Krausz University of Chicago

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