World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
96
Citations
47641
World Ranking
491
National Ranking
53

Genetics

D-Index
93
Citations
44068
World Ranking
957
National Ranking
136

Overview

Matthew T. G. Holden is affiliated with the University of St Andrews in the United Kingdom. Their research spans several fields within biomedical science, focusing primarily on infectious diseases and antimicrobial resistance.

The scientist's work covers significant topics including:

  • Antibiotic Use and Resistance
  • Antibiotic Resistance in Bacteria
  • SARS-CoV-2 and COVID-19 Research
  • Bacterial Identification and Susceptibility Testing
  • Antimicrobial Resistance in Staphylococcus
  • Urinary Tract Infections Management
  • Global Maternal and Child Health

Their main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to subfields such as:

  • Infectious Diseases
  • Epidemiology
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Molecular Medicine

Matthew T. G. Holden has contributed several recent research papers in prominent scientific journals. Some key publications include:

  • "SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway," 2022, Nature Microbiology
  • "Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7," 2021, Cell Reports
  • "Emergence of methicillin resistance predates the clinical use of antibiotics," 2022, Nature
  • "Adeno-associated virus 2 infection in children with non-A-E hepatitis," 2023, Nature
  • "Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland," 2020, Nature Microbiology

The venues where Matthew T. G. Holden most frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Nature Microbiology
  • Microbial Genomics
  • PLoS ONE

The scientist regularly collaborates with a number of frequent co-authors, including:

  • Stephen E. Mshana
  • David M. Aanensen
  • John Stelling
  • Alison Sandeman
  • Martha F. Mushi

Best Publications

  • Roary: Rapid large-scale prokaryote pan genome analysis

    Andrew J. Page;Carla A. Cummins;Martin Hunt;Vanessa K. Wong

  • Genome sequence of Yersinia pestis , the causative agent of plague

    J. Parkhill;B. W. Wren;N. R. Thomson;R. W. Titball

  • Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

    J. Parkhill;G. Dougan;K. D. James;N. R. Thomson

  • Evolution of MRSA During Hospital Transmission and Intercontinental Spread

    Simon R. Harris;Edward J. Feil;Matthew T. G. Holden;Michael A. Quail

  • Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance

    Matthew T. G. Holden;Edward J. Feil;Jodi A. Lindsay;Sharon J. Peacock

  • Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.

    Julian Parkhill;Mohammed Sebaihia;Andrew Preston;Lee D Murphy

  • Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England.

    Erik Volz;Swapnil Mishra;Meera Chand;Jeffrey C. Barrett

  • Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study.

    Laura García-Álvarez;Matthew T G Holden;Heather Lindsay;Cerian R Webb

  • The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

    Mohammed Sebaihia;Brendan W Wren;Peter Mullany;Neil F Fairweather

  • Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei

    Matthew T. G. Holden;Richard W. Titball;Richard W. Titball;Sharon J. Peacock;Sharon J. Peacock;Ana M. Cerdeño-Tárraga

  • SARS-CoV-2 evolution during treatment of chronic infection.

    Steven A. Kemp;Dami A. Collier;Dami A. Collier;Rawlings P. Datir;Isabella A. T. M. Ferreira

  • Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak.

    Claudio U. Köser;Claudio U. Köser;Matthew T.G. Holden;Matthew J. Ellington;Edward J P Cartwright;Edward J P Cartwright

  • Microreact: visualizing and sharing data for genomic epidemiology and phylogeography.

    Silvia Argimón;Khalil Abudahab;Richard J. E. Goater;Artemij Fedosejev

  • COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.

    Victoria Jane Hall;Victoria Jane Hall;Sarah Foulkes;Ayoub Saei;Nick Andrews;Nick Andrews

  • Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria.

    Matthew T.G. Holden;Siri Ram Chhabra;Rocky De Nys;Paul Stead

  • Correction: Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

    Violette Da Cunha;Mark R. Davies;Pierre-Emmanuel Douarre;Isabelle Rosinski-Chupin

  • Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study

    Simon R Harris;Edward J P Cartwright;M Estée Török;Matthew T G Holden

  • SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).

    V J Hall;S Foulkes;A Charlett;A Atti

  • Staphylococcus aureus: superbug, super genome?

    Jodi A. Lindsay;Matthew T.G. Holden

  • Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

    Dami A. Collier;Dami A. Collier;Anna De Marco;Isabella A. T. M. Ferreira;Bo Meng

  • Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study.

    Katherine A Twohig;Tommy Nyberg;Asad Zaidi;Simon Thelwall

Frequent Co-Authors

Julian Parkhill
Julian Parkhill University of Cambridge
Sharon J. Peacock
Sharon J. Peacock University of Cambridge
Stephen D. Bentley
Stephen D. Bentley Wellcome Sanger Institute
Simon R. Harris
Simon R. Harris Wellcome Sanger Institute
Michael A. Quail
Michael A. Quail Wellcome Sanger Institute
Duncan J. Maskell
Duncan J. Maskell University of Melbourne
Edward J. Feil
Edward J. Feil University of Bath
Brendan W. Wren
Brendan W. Wren London School of Hygiene & Tropical Medicine
Gordon Dougan
Gordon Dougan University of Cambridge
David M. Aanensen
David M. Aanensen University of Oxford

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