World's Best Scientists 2026 revealed!

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Medicine

D-Index
101
Citations
44571
World Ranking
7877
National Ranking
4104

Overview

Josephine M. Egan is affiliated with the National Institutes of Health in the United States. Their research spans multiple disciplines primarily within medicine and biochemistry, genetics, and molecular biology. This multidisciplinary approach is reflected in their extensive publication record across diverse subfields and topics.

The main fields of study addressed by Josephine M. Egan include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, subfields of particular focus consist of:

  • Physiology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Surgery
  • Pharmacology

Their work covers a range of scientific topics, which are listed as:

  • Diet and metabolism studies
  • Pancreatic function and diabetes
  • Advanced Neuroimaging Techniques and Applications
  • Adipose Tissue and Metabolism
  • Cannabis and Cannabinoid Research
  • Biochemical Analysis and Sensing Techniques
  • Diabetes and associated disorders

Josephine M. Egan has contributed to numerous scientific articles, with recent publications including:

  • "Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability," 2021, Nature Communications
  • "A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging," 2020, Journal of Internal Medicine
  • "Characterization of Age-Related Differences in the Human Choroid Plexus Volume, Microstructural Integrity, and Blood Perfusion Using Multiparameter Magnetic Resonance Imaging," 2021, Frontiers in Aging Neuroscience
  • "Human Type II Taste Cells Express Angiotensin-Converting Enzyme 2 and Are Infected by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)," 2021, American Journal of Pathology
  • "Disulfiram Treatment Normalizes Body Weight in Obese Mice," 2020, Cell Metabolism

Their publications are frequently found in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Developments in Nutrition
  • Alzheimer's & Dementia
  • Cell Metabolism
  • Journal of the Endocrine Society

Notable frequent collaborators in their research include:

  • Luigi Ferrucci
  • Caio Henrique Mazucanti
  • Jennifer O'Connell
  • Qing-Rong Liu
  • Chee W. Chia

Best Publications

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Genetic mechanisms of critical illness in Covid-19.

    E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  • Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

    Hyeung-Jin Jang;Zaza Kokrashvili;Michael J. Theodorakis;Olga D. Carlson

  • The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

    Wook Kim;Josephine M. Egan

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

    Alisa K. Manning;Alisa K. Manning;Alisa K. Manning;Robert A. Scott;Jonna L. Grimsby

  • The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

    Michelle N. Harvie;Mary Pegington;Mark P. Mattson;Jan Frystyk

  • Mechanisms of action of glucagon-like peptide 1 in the pancreas

    Máire E. Doyle;Josephine M. Egan

  • Diet‐induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle‐aged rats

    Alexis M. Stranahan;Eric D. Norman;Kim Lee;Roy G. Cutler

  • Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.

    Doris A. Stoffers;Timothy J. Kieffer;Mehboob A. Hussain;Daniel J. Drucker

  • Metabolic Syndrome in Men With Prostate Cancer Undergoing Long-Term Androgen-Deprivation Therapy

    Milena Braga-Basaria;Adrian S. Dobs;Denis C. Muller;Michael A. Carducci

  • Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Richa Saxena;Richa Saxena;Claudia Langenberg;Toshiko Tanaka;Toshiko Tanaka

  • Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

    Alexis Michelle Stranahan;Thiruma V. Arumugam;Thiruma V. Arumugam;Roy G. Cutler;Kim Lee

  • GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

    Yazhou Li;Tracy Ann Perry;Mark S. Kindy;Brandon K. Harvey

  • Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

    Riccardo Perfetti;J. I.E. Zhou;Máire E. Doyle;Josephine M. Egan

  • Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

    Z Dastani;Hivert M-F.;Hivert M-F.;N Timpson;Perry Jrb.;Perry Jrb.

  • Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP

    Michael J. Theodorakis;Olga Carlson;Spyros Michopoulos;Máire E. Doyle

  • Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells

    Jie Zhou;Xiaolin Wang;M. A. Pineyro;J. M. Egan

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

Frequent Co-Authors

Luigi Ferrucci
Luigi Ferrucci National Institutes of Health
Jose C. Florez
Jose C. Florez Harvard University
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Erik Ingelsson
Erik Ingelsson Stanford University
Philippe Froguel
Philippe Froguel Imperial College London
Nicole Soranzo
Nicole Soranzo Wellcome Sanger Institute
Toshiko Tanaka
Toshiko Tanaka National Institutes of Health
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore
Joel F. Habener
Joel F. Habener Harvard University
James B. Meigs
James B. Meigs Harvard University

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