Joel F. Habener

Research.com Recognitions

• 2021 - Canada Gairdner International Award
• 2020 - Member of the National Academy of Sciences
• 2020 - Warren Alpert Foundation Prize For identifying Glucagon-like peptides and leading the field with studies extending from cells to humans, culminating in the development of these peptides as therapeutic agents for treating diabetes and short bowel syndrome.
• 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

  David Ron;Joel F. Habener

  1666
  Citations

• Glucagon-like peptide 1 (GLP-1)

  T.D. Müller;B. Finan;S.R. Bloom;D. D'Alessio

  1608
  Citations

• Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

  Gang Xu;D. A. Stoffers;J. F. Habener;S. Bonner-Weir

  1605
  Citations

• Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence.

  Doris A. Stoffers;Noah T. Zinkin;Violeta Stanojevic;William L. Clarke

  1333
  Citations

• The glucagon-like peptides.

  Timothy James Kieffer;Joel Francis Habener

  1316
  Citations

• Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes

  Henryk Zulewski;Elizabeth J. Abraham;Melissa J. Gerlach;Philip B. Daniel

  1249
  Citations

• Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

  Svetlana Mojsov;Gordon C. Weir;Joel F. Habener

  1189
  Citations

• Early-onset type-II diabetes mellitus (MODY4) linked to IPF1.

  D A Stoffers;J Ferrer;J Ferrer;W L Clarke;J F Habener

  1188
  Citations

• Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

  Daniel J. Drucker;Jacques Philippe;Svetlana Mojsov;William L. Chick

  1122
  Citations

• Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA.

  J. P. Hoeffler;T. E. Meyer;Yungdae Yun;J. L. Jameson

  919
  Citations

• Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

  S Mojsov;G Heinrich;I B Wilson;M Ravazzola

  877
  Citations

• Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

  Brasier Ar;Tate Je;Habener Jf

  813
  Citations

• Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis.

  Beat Müller;Jon C. White;Eric S. Nylén;Richard H. Snider

  799
  Citations

• Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.

  Doris A. Stoffers;Timothy J. Kieffer;Mehboob A. Hussain;Daniel J. Drucker

  794
  Citations

• Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

  George G. Holz;Willem M. Kühtreiber;Joel F. Habener

  793
  Citations

• Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor.

  B P Bullock;R S Heller;J F Habener

  788
  Citations

• Leptin Suppression of Insulin Secretion by the Activation of ATP-Sensitive K + Channels in Pancreatic β-Cells

  Timothy J. Kieffer;R. Scott Heller;Colin A. Leech;George G. Holz

  728
  Citations

• Cyclic Adenosine 3′,5′-Monophosphate Response Element Binding Protein (CREB) and Related Transcription-Activating Deoxyribonucleic Acid-Binding Proteins*

  Terry E. Meyer;Joel F. Habener

  700
  Citations

• Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat.

  D J Campbell;J F Habener

  697
  Citations

• The adipoinsular axis: effects of leptin on pancreatic β-cells

  Timothy J. Kieffer;Joel F. Habener

  672
  Citations