World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
116
Citations
48475
World Ranking
4355
National Ranking
2376

Research.com Recognitions

  • 1967 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gordon C. Weir is affiliated with Harvard University in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology.

The scientist has contributed extensively to the understanding of pancreatic function and diabetes, with key topics including pancreatic function and diabetes, diabetes management and research, diabetes and associated disorders, metabolism related to diabetes and cancer, 3D printing in biomedical research, pluripotent stem cells research, and tissue engineering and regenerative medicine.

Among the recent papers authored or co-authored by Gordon C. Weir are:

  • Inadequate β-cell mass is essential for the pathogenesis of type 2 diabetes, 2020, The Lancet Diabetes & Endocrinology
  • The β-cell glucose toxicity hypothesis: Attractive but difficult to prove, 2021, Metabolism

They have also contributed as a co-author to works such as:

  • A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells, 2020, Nature Biomedical Engineering
  • Beta cell identity changes with mild hyperglycemia: Implications for function, growth, and vulnerability, 2020, Molecular Metabolism
  • C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis, 2023, The Lancet Diabetes & Endocrinology

Frequent co-authors include Susan Bonner-Weir (11 collaborations), Jennifer Hollister-Lock (4 collaborations), Jason L. Gaglia (2 collaborations), Omid Veiseh (2 collaborations), and Dale L. Greiner (2 collaborations).

Their publications are often found in these venues:

  • The Lancet Diabetes & Endocrinology (3 publications)
  • Molecular Metabolism (2 publications)
  • Nature Biomedical Engineering (1 publication)
  • Metabolism (1 publication)
  • Diabetes (1 publication)

Gordon C. Weir's research spans several subfields including surgery, endocrinology, diabetes and metabolism, genetics, molecular biology, and biomedical engineering. Their work includes a significant amount within surgery (17 publications) and endocrinology, diabetes and metabolism (14 publications), reflecting a cross-disciplinary approach to medical science.

In recognition of their contributions, they were named a Fellow of the American Association for the Advancement of Science (AAAS) in 1967.

Best Publications

  • Induced pluripotent stem cells generated without viral integration

    Matthias Stadtfeld;Masaki Nagaya;Masaki Nagaya;Jochen Utikal;Gordon Weir;Gordon Weir

  • In vitro cultivation of human islets from expanded ductal tissue

    Susan Bonner-Weir;Monica Taneja;Gordon C. Weir;Krystyna Tatarkiewicz

  • Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes

    Gordon C. Weir;Susan Bonner-Weir

  • Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

    Svetlana Mojsov;Gordon C. Weir;Joel F. Habener

  • β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

    Philippe A. Halban;Kenneth S. Polonsky;Donald W. Bowden;Meredith A. Hawkins

  • Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

    Alfredo Lorenzo;Bronwyn Razzaboni;Gordon C. Weir;Bruce A. Yankner

  • Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

    Omid Veiseh;Joshua C. Doloff;Minglin Ma;Arturo J. Vegas

  • Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes.

    Jean-Christophe Jonas;Arun Sharma;Wendy Hasenkamp;Hasan Ilkova

  • Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

    Arturo J Vegas;Arturo J Vegas;Arturo J Vegas;Omid Veiseh;Omid Veiseh;Mads Gürtler;Jeffrey R Millman

  • Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

    Adi F. Gazdar;William L. Chick;Herbert K. Oie;Harvie L. Sims

  • New sources of pancreatic beta-cells.

    Susan Bonner-Weir;Gordon C Weir

  • Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.

    S Bonner-Weir;D F Trent;G C Weir

  • Beta-cell adaptation and decompensation during the progression of diabetes.

    Gordon C. Weir;David Ross Laybutt;Hideaki Kaneto;Susan Bonner-Weir

  • Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion.

    Susan Bonner-Weir;Deanna Deery;John L Leahy;Gordon C Weir

  • Vulnerability of Islets in the Immediate Posttransplantation Period: Dynamic Changes in Structure and Function

    Alberto M Davalli;Luisa Scaglia;David H Zangen;Jennifer Hollister

  • Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

    Arturo J Vegas;Arturo J Vegas;Arturo J Vegas;Omid Veiseh;Joshua C Doloff;Joshua C Doloff;Minglin Ma;Minglin Ma;Minglin Ma

  • β-Cell Dysfunction Induced by Chronic Hyperglycemia: Current Ideas on Mechanism of Impaired Glucose-Induced Insulin Secretion

    John L Leahy;Susan Bonner-Weir;Gordon C Weir

  • Downregulation of GLP-1 and GIP Receptor Expression by Hyperglycemia: Possible Contribution to Impaired Incretin Effects in Diabetes

    Gang Xu;Hideaki Kaneto;D. Ross Laybutt;Valerie F. Duvivier-Kali

  • The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration.

    A Sharma;D H Zangen;P Reitz;M Taneja

  • Responses of Neonatal Rat Islets to Streptozotocin: Limited B-Cell Regeneration and Hyperglycemia

    S Bonner-Weir;D F Trent;R N Honey;G C Weir

Frequent Co-Authors

Susan Bonner-Weir
Susan Bonner-Weir Harvard University
Dale L. Greiner
Dale L. Greiner University of Massachusetts Chan Medical School
Philippe A. Halban
Philippe A. Halban University of Geneva
Joel F. Habener
Joel F. Habener Harvard University
Arun K. Sharma
Arun K. Sharma University of Calcutta
Dennis C. Sgroi
Dennis C. Sgroi Harvard University
Douglas A. Melton
Douglas A. Melton Harvard University
George L. King
George L. King Harvard University

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