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Neuroscience

D-Index
57
Citations
16986
World Ranking
4279
National Ranking
1937

Overview

Michael J. Pontecorvo is affiliated with Eli Lilly in the United States and focuses on research in the medical field, particularly within dementia and cognitive impairment. Their work is concentrated on Alzheimer's disease research and treatments, with significant contributions to functional brain connectivity studies and medical imaging techniques. The scientist's expertise spans psychiatry and mental health, physiology, radiology including nuclear medicine and imaging, cognitive neuroscience, and neurology.

Their recent scientific publications include the following:

  • Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease, 2022, JAMA Neurology
  • Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease, 2022, Brain
  • Four distinct trajectories of tau deposition identified in Alzheimer's disease, 2021, Nature Medicine
  • Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease, 2021, JAMA Neurology
  • Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes, 2020, JAMA Neurology

Frequent coauthors of Michael J. Pontecorvo include:

  • Oskar Hansson
  • Rik Ossenkoppele
  • Michael D. Devous
  • Ruben Smith
  • Sergey Shcherbinin

The scientist's research is frequently published in the following venues:

  • Alzheimer's & Dementia
  • JAMA Neurology
  • Alzheimer's Research & Therapy
  • European Journal of Nuclear Medicine and Molecular Imaging
  • Brain

Main fields of study emphasize medicine, with detailed subfields including psychiatry and mental health, physiology, radiology and nuclear medicine imaging, cognitive neuroscience, and neurology.

Core topics in the work of Michael J. Pontecorvo comprise dementia and cognitive impairment research, Alzheimer's disease research and treatments, functional brain connectivity studies, medical imaging techniques and applications, advanced neuroimaging techniques, neurological disease mechanisms and treatments, as well as proteins such as S100 and annexins.

Best Publications

  • Use of Florbetapir-PET for Imaging β-Amyloid Pathology

    Christopher M. Clark;Julie A. Schneider;Barry J. Bedell;Thomas G. Beach

  • The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET

    William E. Klunk;William E. Klunk;Robert A. Koeppe;Julie C. Price;Tammie L. Benzinger;Tammie L. Benzinger

  • In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18).

    Dean F. Wong;Paul B. Rosenberg;Yun Zhou;Anil Kumar

  • Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

    Christopher M Clark;Michael J Pontecorvo;Thomas G Beach;Barry J Bedell

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease

    Unknown

  • The Cholinergic Hypothesis: A Historical Overview, Current Perspective, and Future Directions

    Raymond T. Bartus;Reginald L. Dean;Michael J. Pontecorvo;Charles Flicker

  • Amyloid-β Imaging with Pittsburgh Compound B and Florbetapir: Comparing Radiotracers and Quantification Methods

    Susan M. Landau;Susan M. Landau;Susan M. Landau;Christopher Breault;Abhinay D. Joshi;Michael Pontecorvo

  • Performance Characteristics of Amyloid PET with Florbetapir F 18 in Patients with Alzheimer's Disease and Cognitively Normal Subjects

    Abhinay D. Joshi;Michael J. Pontecorvo;Chrisopher M. Clark;Alan P. Carpenter

  • Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients

    Eric R. Siemers;Karen L. Sundell;Christopher Carlson;Michael Case

  • Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid.

    Susan M. Landau;Susan M. Landau;Ming Lu;Abhinay D. Joshi;Michael Pontecorvo

  • Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes

    Adam S Fleisher;Michael J Pontecorvo;Michael D Devous;Ming Lu

  • Using Positron Emission Tomography and Florbetapir F 18 to Image Cortical Amyloid in Patients With Mild Cognitive Impairment or Dementia Due to Alzheimer Disease

    Adam S. Fleisher;Kewei Chen;Xiaofen Liu;Auttawut Roontiva

  • Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition.

    Michael J. Pontecorvo;Michael D. Devous;Michael Navitsky;Ming Lu

  • Amyloid PET imaging in Alzheimer’s disease: a comparison of three radiotracers

    S. M. Landau;S. M. Landau;B. A. Thomas;L. Thurfjell;M. Schmidt

  • Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies.

    Raymond T. Bartus;Raymond T. Bartus;Charles Flicker;Reginald L. Dean;Michael Pontecorvo

  • Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging.

    Rik Ossenkoppele;Rik Ossenkoppele;Ruben Smith;Niklas Mattsson-Carlgren;Colin Groot

  • Individual differences in aging: Behavioral and neurobiological correlates

    Alicja L. Markowska;William S. Stone;Donald K. Ingram;Jay Reynolds

  • Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline A multicenter study

    P. Murali Doraiswamy;Reisa A. Sperling;R. Edward Coleman;Keith A. Johnson

  • Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging.

    Keith A. Johnson;Reisa A. Sperling;Christopher M. Gidicsin;Jeremy S. Carmasin

  • Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease

    Adam S. Fleisher;Kewei Chen;Xiaofen Liu;Napatkamon Ayutyanont

  • Florbetapir F 18 amyloid PET and 36-month cognitive decline:a prospective multicenter study

    P M Doraiswamy;R A Sperling;K Johnson;E M Reiman

  • Double-blind, placebo-controlled, proof-of-concept trial of bexarotene Xin moderate Alzheimer's disease.

    Jeffrey L. Cummings;Kate Zhong;Jefferson W. Kinney;Chelcie Heaney

Frequent Co-Authors

Michael D. Devous
Michael D. Devous Avid Radiopharmaceuticals
Adam S. Fleisher
Adam S. Fleisher Avid Radiopharmaceuticals
Eric M. Reiman
Eric M. Reiman Arizona State University
Reisa A. Sperling
Reisa A. Sperling Brigham and Women's Hospital
William J. Jagust
William J. Jagust University of California, Berkeley
Rik Ossenkoppele
Rik Ossenkoppele Lund University
Julie A. Schneider
Julie A. Schneider Rush University Medical Center
Susan M. Landau
Susan M. Landau University of California, Berkeley
Ruben Smith
Ruben Smith Lund University

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