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Medicine

D-Index
82
Citations
21995
World Ranking
16247
National Ranking
8168

Overview

Alvin C. Powers is affiliated with Vanderbilt University Medical Center in the United States. Their research spans multiple fields of study, primarily focusing on medicine and biochemistry, genetics, and molecular biology.

The main subfields of their work include surgery, endocrinology, diabetes and metabolism, genetics, molecular biology, and oncology. Within these areas, Powers concentrates on topics related to pancreatic function and diabetes, diabetes and associated disorders, diabetes management and research, diabetes treatment and management, pancreatic and hepatic oncology research, liver disease diagnosis and treatment, and pancreatitis pathology and treatment.

Frequent coauthors in their research include Marcela Briššová, Diane C. Saunders, Greg Poffenberger, J. J. Wright, and Chunhua Dai.

Powers has published extensively in various academic venues. The most frequent publication venues are Diabetes, bioRxiv (Cold Spring Harbor Laboratory), Cell Metabolism, Journal of Clinical Investigation, and Diabetes Care.

Selected recent papers authored or co-authored by Powers include:

  • Type 1 diabetes mellitus: much progress, many opportunities (2021), Journal of Clinical Investigation
  • Endocrine toxicities of immune checkpoint inhibitors (2021), Nature Reviews Endocrinology
  • SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells (2020), Cell Metabolism
  • The Human Islet: Mini-Organ With Mega-Impact (2021), Endocrine Reviews
  • Human islet T cells are highly reactive to preproinsulin in type 1 diabetes (2021), Proceedings of the National Academy of Sciences

Powers' body of work encompasses 188 publications in medicine and 108 in biochemistry, genetics, and molecular biology. Their research output demonstrates a consistent focus on diabetes-related conditions and pancreatic studies. The integration of molecular biology, genetics, and clinical approaches is evident throughout their publications.

Best Publications

  • β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

    Philippe A. Halban;Kenneth S. Polonsky;Donald W. Bowden;Meredith A. Hawkins

  • Assessment of Human Pancreatic Islet Architecture and Composition by Laser Scanning Confocal Microscopy

    Marcela Brissova;Michael J. Fowler;Wendell E. Nicholson;Anita Chu

  • Inactivation of specific β cell transcription factors in type 2 diabetes

    Shuangli Guo;Chunhua Dai;Min Guo;Brandon Taylor

  • Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion

    Thomas Delong;Timothy A. Wiles;Rocky L. Baker;Brenda Bradley

  • Pancreatic Islet Production of Vascular Endothelial Growth Factor-A Is Essential for Islet Vascularization, Revascularization, and Function

    Marcela Brissova;Alena Shostak;Masakazu Shiota;Peter O. Wiebe

  • Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.

    Marcela Brissova;Masakazu Shiota;Wendell E. Nicholson;Maureen Gannon

  • An encapsulation system for the immunoisolation of pancreatic islets

    Taylor Wang;Igor Lacík;Marcela Brissová;Amrutur V. Anilkumar

  • Conditional gene targeting in mouse pancreatic β-cells: Analysis of ectopic Cre transgene expression in the brain

    Barton Wicksteed;Marcela Brissova;Wenbo Yan;Darren M. Opland

  • Impact of Medical Student Research in the Development of Physician-Scientists

    Solomon S. Solomon;Stephen C. Tom;James Pichert;David Wasserman

  • VEGF-A recruits a proangiogenic MMP-9–delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue

    Gustaf Christoffersson;Evelina Vågesjö;Jennifer Vandooren;Majken Lidén

  • Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen.

    M Pietropaolo;L Castaño;S Babu;R Buelow

  • Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

    Jenny Aurielle B Babon;Megan E DeNicola;David M Blodgett;Inne Crèvecoeur

  • p16 Ink4a -induced senescence of pancreatic beta cells enhances insulin secretion

    Aharon Helman;Agnes Klochendler;Narmen Azazmeh;Yael Gabai

  • Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets

    Marcela Brissova;Michael Fowler;Peter Wiebe;Alena Shostak

  • Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains

    Eric D. Berglund;Candice Y. Li;Greg Poffenberger;Julio E. Ayala

  • Endocrine toxicities of immune checkpoint inhibitors

    Jordan J. Wright;Alvin C. Powers;Alvin C. Powers;Douglas B. Johnson

  • Glucose Intolerance Due to Insulin Resistance in Patients with Spinal Cord Injuries

    William C Duckworth;Solomon S Solomon;Panduranga Jallepalli;Chris Heckemeyer

  • Liver-Specific Disruption of the Murine Glucagon Receptor Produces α-Cell Hyperplasia: Evidence for a Circulating α-Cell Growth Factor

    Christine Longuet;Ana M. Robledo;E. Danielle Dean;Chunhua Dai

  • Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

    H. Efsun Arda;Lingyu Li;Jennifer Tsai;Eduardo A. Torre

  • b-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and

    Universityof Geneva;Philippe A. Halban;Kenneth S. Polonsky;Donald W. Bowden

Frequent Co-Authors

Mark A. Atkinson
Mark A. Atkinson University of Florida
Roland Stein
Roland Stein Vanderbilt University
Dale L. Greiner
Dale L. Greiner University of Massachusetts Chan Medical School
Leonard D. Shultz
Leonard D. Shultz Jackson Laboratory
Shawn Levy
Shawn Levy Vanderbilt University
David W. Piston
David W. Piston Washington University in St. Louis
James M. May
James M. May Vanderbilt University Medical Center
Ali Naji
Ali Naji University of Pennsylvania
Martha Campbell-Thompson
Martha Campbell-Thompson University of Florida
Klaus H. Kaestner
Klaus H. Kaestner University of Pennsylvania

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