D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 86 Citations 24,854 208 World Ranking 745 National Ranking 419
Medicine D-index 89 Citations 27,551 218 World Ranking 6138 National Ranking 3404

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Transcription factor

The scientist’s investigation covers issues in Cell biology, Molecular biology, Cellular differentiation, Internal medicine and Endocrinology. His Cell biology research is multidisciplinary, incorporating elements of Genetics, Endoderm, Immunology, Pancreas and Cell type. His biological study spans a wide range of topics, including Gene expression, Liver regeneration, Messenger RNA, microRNA and Sp1 transcription factor.

His Cellular differentiation study combines topics in areas such as Intestinal epithelium, KLF4, Stem cell, Regulation of gene expression and PDX1. His Endocrinology study combines topics from a wide range of disciplines, such as Cell, Hepatocyte nuclear factor 4, Winged Helix and Transplantation. His studies in Transcription factor integrate themes in fields like Promoter and Glucocorticoid receptor.

His most cited work include:

  • Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ) (1603 citations)
  • DNA binding of the glucocorticoid receptor is not essential for survival (977 citations)
  • Unified nomenclature for the winged helix/forkhead transcription factors (947 citations)

What are the main themes of his work throughout his whole career to date?

Klaus H. Kaestner mostly deals with Cell biology, Internal medicine, Endocrinology, Transcription factor and Molecular biology. His research in Cell biology intersects with topics in Chromatin, Embryonic stem cell, Immunology and Cellular differentiation. Within one scientific family, Klaus H. Kaestner focuses on topics pertaining to Cancer research under Cellular differentiation, and may sometimes address concerns connected to Carcinogenesis.

His Internal medicine study frequently draws connections to other fields, such as CREB. His Transcription factor research is multidisciplinary, incorporating perspectives in Regulation of gene expression and Gene expression. His Molecular biology research includes elements of Promoter and Hepatocyte nuclear factors.

He most often published in these fields:

  • Cell biology (35.19%)
  • Internal medicine (24.07%)
  • Endocrinology (22.92%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (35.19%)
  • Cancer research (13.89%)
  • Transcription factor (21.76%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Cancer research, Transcription factor, Islet and Internal medicine. His Cell biology research incorporates elements of Chromatin, Epigenetics, Gene and Cellular differentiation. His Cellular differentiation research focuses on Stem cell and how it relates to Wnt signaling pathway.

His study in Cancer research is interdisciplinary in nature, drawing from both FOXA1, FOXP3 and Bladder cancer. The concepts of his Transcription factor study are interwoven with issues in Regulator, Embryonic stem cell and Histone. His work in Internal medicine is not limited to one particular discipline; it also encompasses Endocrinology.

Between 2015 and 2021, his most popular works were:

  • Cytoplasmic chromatin triggers inflammation in senescence and cancer (360 citations)
  • Single-cell transcriptomics of the human endocrine pancreas (201 citations)
  • The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation. (190 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

Cell biology, Cellular differentiation, Enteroendocrine cell, Cell and Genetics are his primary areas of study. Klaus H. Kaestner has included themes like Chromatin, Regulation of gene expression, Gene and Glucose homeostasis in his Cell biology study. The various areas that Klaus H. Kaestner examines in his Cellular differentiation study include Progenitor cell, Transdifferentiation and Stem cell.

He has researched Enteroendocrine cell in several fields, including Cell type, Pancreas and Pancreatic islets. His research integrates issues of Molecular biology and Gene expression in his study of Pancreatic islets. Endocrinology and Internal medicine are inextricably linked to his Hormone research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho;James Mu;Jason K. Kim;Jason K. Kim;Joanne L. Thorvaldsen.
Science (2001)

2171 Citations

Unified nomenclature for the winged helix/forkhead transcription factors

Klaus H. Kaestner;Walter Knöchel;Daniel E. Martínez.
Genes & Development (2000)

1384 Citations

DNA binding of the glucocorticoid receptor is not essential for survival

Holger M Reichardt;Klaus H Kaestner;Jan Tuckermann;Oliver Kretz.
Cell (1998)

1266 Citations

Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm

A.P. Monaghan;K.H. Kaestner;E. Grau;G. Schutz.
Development (1993)

689 Citations

The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.

Jonathan P. Katz;Nathalie Perreault;Bree G. Goldstein;Catherine S. Lee.
Development (2002)

617 Citations

Severe impairment of spermatogenesis in mice lacking the CREM gene

Julie A. Blendy;Klaus H. Kaestner;Gerhard F. Weinbauer;Eberhard Nieschlag.
Nature (1996)

609 Citations

Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis.

Fereshteh Parviz;Christine Matullo;Wendy D Garrison;Laura Savatski.
Nature Genetics (2003)

606 Citations

The evolution of Fox genes and their role in development and disease.

Sridhar Hannenhalli;Klaus H. Kaestner.
Nature Reviews Genetics (2009)

574 Citations

The initiation of liver development is dependent on Foxa transcription factors.

Catherine S. Lee;Joshua R. Friedman;James T. Fulmer;Klaus H. Kaestner.
Nature (2005)

549 Citations

Krüppel-like factor 4 regulates macrophage polarization

Xudong Liao;Nikunj Sharma;Fehmida Kapadia;Guangjin Zhou.
Journal of Clinical Investigation (2011)

539 Citations

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