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D-Index & Metrics

Molecular Biology

D-Index
88
Citations
33436
World Ranking
777
National Ranking
411

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kenneth S. Zaret is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology. Additional areas addressed in their work include Oncology, Plant Science, Cancer Research, and Genetics.

The scientist's main research topics cover Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, CRISPR and Genetic Engineering, Pancreatic and Hepatic Oncology Research, RNA Research and Splicing, RNA modifications and cancer, and Protein Degradation and Inhibitors.

Frequent coauthors in their research include Jonathan Lerner, Greg Donahue, Ryan L. McCarthy, Naomi Takenaka, and Andrew Katznelson.

They have published multiple papers in notable venues, with repeated contributions to bioRxiv (Cold Spring Harbor Laboratory), Nature Cell Biology, STAR Protocols, Molecular Cell, and Science.

Their recent significant publications include:

  • "Pioneer Transcription Factors Initiating Gene Network Changes" (2020) published in Annual Review of Genetics
  • "Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids" (2021) published in Cell Stem Cell
  • "Two-Parameter Mobility Assessments Discriminate Diverse Regulatory Factor Behaviors in Chromatin" (2020) published in Molecular Cell
  • "Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin" (2023) published in Science
  • "Pioneer factors: roles and their regulation in development" (2023) published in Trends in Genetics

Kenneth S. Zaret was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Pioneer transcription factors: establishing competence for gene expression

    Kenneth S. Zaret;Jason S. Carroll

  • Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4

    Lisa Ann Cirillo;Frank Robert Lin;Isabel Cuesta;Dara Friedman

  • DNA sequence required for efficient transcription termination in yeast.

    Kenneth S. Zaret;Fred Sherman

  • miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

    Jinhong Chang;Emmanuelle Nicolas;Debora Marks;Chris Sander

  • Liver organogenesis promoted by endothelial cells prior to vascular function.

    Kunio Matsumoto;Kunio Matsumoto;Hideyuki Yoshitomi;Janet Rossant;Janet Rossant;Kenneth S. Zaret

  • Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

    Abdenour Soufi;Greg Donahue;Kenneth S. Zaret

  • Initiation of Mammalian Liver Development from Endoderm by Fibroblast Growth Factors

    Joonil Jung;Minghua Zheng;Mitchell Goldfarb;Kenneth S. Zaret

  • Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

    Jennifer M. Rossi;N. Ray Dunn;Brigid L.M. Hogan;Kenneth S. Zaret

  • Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming

    Abdenour Soufi;Meilin Fernandez Garcia;Artur Jaroszewicz;Nebiyu Osman

  • The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins.

    Siew-Lan Ang;A. Wierda;D. Wong;K. A. Stevens

  • A bipotential precursor population for pancreas and liver within the embryonic endoderm.

    Gail Deutsch;Joonil Jung;Minghua Zheng;José Lóra

  • Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.

    R Gualdi;P Bossard;M Zheng;Y Hamada

  • Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis.

    Fereshteh Parviz;Christine Matullo;Wendy D Garrison;Laura Savatski

  • Generation and Regeneration of Cells of the Liver and Pancreas

    Kenneth S. Zaret;Markus Grompe

  • Pioneer transcription factors in cell reprogramming

    Makiko Iwafuchi-Doi;Kenneth S. Zaret

  • Regulatory phases of early liver development: paradigms of organogenesis.

    Kenneth S. Zaret

  • Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

    Kenneth S. Zaret;Keith R. Yamamoto

  • Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome

    Lisa A. Cirillo;Clifton E. McPherson;Pascale Bossard;Kimberly Stevens

  • H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

    Justin S. Becker;Dario Nicetto;Kenneth S. Zaret

  • GATA transcription factors as potentiators of gut endoderm differentiation

    Pascale Bossard;Kenneth S. Zaret

Frequent Co-Authors

Stephen T. Smale
Stephen T. Smale University of California, Los Angeles
Pilar Santisteban
Pilar Santisteban Spanish National Research Council
Fred Sherman
Fred Sherman University of Rochester
Frédéric Relaix
Frédéric Relaix Paris-Est Créteil University
Klaus H. Kaestner
Klaus H. Kaestner University of Pennsylvania
Janet Rossant
Janet Rossant University of Toronto
Matteo Pellegrini
Matteo Pellegrini University of California, Los Angeles
Palle Serup
Palle Serup University of Copenhagen
Frédéric P. Lemaigre
Frédéric P. Lemaigre Université Catholique de Louvain

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