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D-Index & Metrics

Molecular Biology

D-Index
63
Citations
16871
World Ranking
1788
National Ranking
125

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Maike Sander is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research is primarily situated at the intersection of medicine, biochemistry, genetics, and molecular biology, focusing extensively on pancreatic function and diabetes.

The scientist's work covers several specialized subfields, including surgery, genetics, molecular biology, endocrinology, diabetes and metabolism, and cancer research. Their research topics include pancreatic function and diabetes, diabetes and associated disorders, diabetes management and research, epigenetics and DNA methylation, genetics and neurodevelopmental disorders, single-cell and spatial transcriptomics, and cancer-related molecular mechanisms research.

Recent papers authored or co-authored by Maike Sander include the following:

  • Interpreting type 1 diabetes risk with genetics and single-cell epigenomics, 2021, Nature
  • Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk, 2021, Nature Genetics
  • Systematic analysis of binding of transcription factors to noncoding variants, 2021, Nature
  • Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes, 2023, Developmental Cell
  • Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes, 2023, Nature Genetics

Frequent co-authors collaborating with Sander include Kyle J. Gaulton, Joshua Chiou, Han Zhu, Gaowei Wang, and Matthew Wortham.

Publications by Maike Sander have appeared predominantly in bioRxiv (Cold Spring Harbor Laboratory), with significant contributions also in Diabetes, Journal of Clinical Investigation, Zenodo (CERN European Organization for Nuclear Research), and Nature.

Maike Sander is recognized as a member of the Association of American Physicians.

Best Publications

  • Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

    Janel L. Kopp;Guido von Figura;Erin Mayes;Fen-Fen Liu

  • Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

    M Sander;A Neubüser;J Kalamaras;H C Ee

  • SOX9 is required for maintenance of the pancreatic progenitor cell pool

    Philip A. Seymour;Kristine K. Freude;Man N. Tran;Erin E. Mayes

  • Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

    M. Sander;L. Sussel;J. Conners;D. Scheel

  • Inactivation of specific β cell transcription factors in type 2 diabetes

    Shuangli Guo;Chunhua Dai;Min Guo;Brandon Taylor

  • Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

    Unknown

  • Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

    Ignasi Morán;İldem Akerman;Martijn van de Bunt;Martijn van de Bunt;Ruiyu Xie

  • Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.

    Joan Font-Burgada;Shabnam Shalapour;Suvasini Ramaswamy;Brian Hsueh

  • The beta cell transcription factors and development of the pancreas.

    M. Sander;Michael S. German

  • Pancreas organogenesis: from lineage determination to morphogenesis.

    Unknown

  • Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

    Unknown

  • The MafA transcription factor appears to be responsible for tissue-specific expression of insulin.

    Taka-aki Matsuoka;Isabella Artner;Eva Henderson;Anna Means

  • Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

    Maike Sander;Sussan Paydar;Johan Ericson;James Briscoe

  • Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

    Unknown

  • Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification.

    Anna Vallstedt;Jonas Muhr;Alexandre Pattyn;Alessandra Pierani

  • Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

    Joshua Chiou;Joshua Chiou;Ryan J. Geusz;Mei-Lin Okino;Jee Yun Han

  • Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.

    Rodolphe Carpentier;Regina Español Suñer;Noémi van Hul;Janel L. Kopp

  • Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

    Briana E. Rockich;Steven M. Hrycaj;Hung Ping Shih;Melinda S. Nagy

  • Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

    Ashleigh E Schaffer;Brandon L Taylor;Jacqueline R Benthuysen;Jingxuan Liu

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

Frequent Co-Authors

Kyle J. Gaulton
Kyle J. Gaulton University of California, San Diego
Bing Ren
Bing Ren New York Genome Center
Detlev Ganten
Detlev Ganten Max Delbrück Center for Molecular Medicine
Klaus H. Kaestner
Klaus H. Kaestner University of Pennsylvania
Michael Bader
Michael Bader Max Delbrück Center for Molecular Medicine
Lori Sussel
Lori Sussel University of Colorado Denver
Johan Ericson
Johan Ericson Karolinska Institute
Michael S. German
Michael S. German University of California, San Francisco
Kelly A. Frazer
Kelly A. Frazer University of California, San Diego
Orian S. Shirihai
Orian S. Shirihai University of California, Los Angeles

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