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Biology and Biochemistry

D-Index
66
Citations
19606
World Ranking
8527
National Ranking
3834

Overview

Todd L. Edwards is affiliated with Vanderbilt University Medical Center in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a significant focus on genetics and related subfields including obstetrics and gynecology, molecular biology, pediatrics, perinatology and child health, as well as cardiology and cardiovascular medicine.

Their main topics of research cover various aspects of genetic associations and epidemiology, birth, development, and health, and specialized areas such as endometriosis research and treatment. Additional research topics include aortic aneurysm repair treatments, genomics and rare diseases, uterine myomas and treatments, and liver disease diagnosis and treatment.

Todd L. Edwards has contributed to a number of scientific publications, with notable papers including:

  • Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis (2020, Nature Genetics)
  • Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19 (2021, Nature Medicine)
  • The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions (2023, Nature Genetics)
  • A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation (2022, Nature Genetics)
  • Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments (2021, Nature Genetics)

Their frequent coauthors include Jacklyn N. Hellwege, Digna R. Velez Edwards, Ayush Giri, Joseph H. Breeyear, and Yan V. Sun. These collaborations indicate a network of research partners engaged in the fields of genetics and medicine.

Edwards has published extensively in several venues, with a strong presence in bioRxiv (Cold Spring Harbor Laboratory) and UNC Libraries, where they have contributed 20 publications each. Their work also appears in journals such as Hypertension, Nature Communications, and Nature Genetics.

Best Publications

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

    Alvaro N. Barbeira;Scott P. Dickinson;Rodrigo Bonazzola;Jiamao Zheng

  • Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.

    Todd L. Edwards;Todd L. Edwards;William K. Scott;Cherylyn Almonte;Amber Burt

  • Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

    A Giri;J N Hellwege;J M Keaton;J M Keaton;J Park

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

    Norihiro Kato;Marie Loh;Marie Loh;Marie Loh;Fumihiko Takeuchi;Niek Verweij

  • Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

    Ulrike Peters;Ulrike Peters;Shuo Jiao;Fredrick R. Schumacher;Carolyn M. Hutter;Carolyn M. Hutter

  • Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

    Xiaofeng Zhu;Tao Feng;Tao Feng;Bamidele O. Tayo;Jingjing Liang

  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

    Adrienne Tin;Jonathan Marten;Victoria L. Halperin Kuhns;Yong Li

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.

    Joseph F Solus;Brenda J Arietta;James R Harris;David P Sexton

  • Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

    Yadav Sapkota;Yadav Sapkota;Valgerdur Steinthorsdottir;Andrew P. Morris;Andrew P. Morris;Amelie Fassbender

  • Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

    Chunyu Liu;Aldi T Kraja;Jennifer A Smith;Jennifer A Brody

  • Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations

    Nora Franceschini;Ervin Fox;Zhaogong Zhang;Zhaogong Zhang;Todd L. Edwards

  • Rare and low-frequency coding variants alter human adult height

    Eirini Marouli;Mariaelisa Graff;Carolina Medina-Gomez;Ken Sin Lo

  • Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

    Lisa Bastarache;Jacob J. Hughey;Scott Hebbring;Joy Marlo

  • Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

    Siddhartha P. Kar;Jonathan Beesley;Ali Amin Al Olama;Kyriaki Michailidou

  • Population Stratification in Genetic Association Studies.

    Jacklyn N. Hellwege;Jacob M. Keaton;Ayush Giri;Xiaoyi Gao

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Bruce M. Psaty
Bruce M. Psaty University of Washington
Wei Zheng
Wei Zheng Vanderbilt University Medical Center
Tonu Esko
Tonu Esko University of Tartu
Christopher J. O'Donnell
Christopher J. O'Donnell Harvard Medical School
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Ruth J. F. Loos
Ruth J. F. Loos University of Copenhagen
J. Michael Gaziano
J. Michael Gaziano Brigham and Women's Hospital
Andrew P. Morris
Andrew P. Morris University of Liverpool
Paul M. Ridker
Paul M. Ridker Brigham and Women's Hospital
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center

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