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Molecular Biology

D-Index
51
Citations
12030
World Ranking
2489
National Ranking
1230

Overview

Ajay B. Chitnis is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in cell biology and molecular biology as well. Additional subfields include biophysics, cancer research, and media technology.

The scientist's work extensively covers topics related to zebrafish biomedical research applications, developmental biology and gene regulation, and congenital heart defects research. Other areas of study include proteoglycans and glycosaminoglycans research, microRNA in disease regulation, advanced fluorescence microscopy techniques, and cell image analysis techniques.

Ajay B. Chitnis has published research in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Biotechnology
  • npj Regenerative Medicine
  • eLife
  • Science

Some of the recent papers authored or co-authored by Ajay B. Chitnis include:

  • Rapid image deconvolution and multiview fusion for optical microscopy, 2020, Nature Biotechnology
  • The Warburg effect is necessary to promote glycosylation in the blastema during zebrafish tail regeneration, 2021, npj Regenerative Medicine
  • Zebrafish Posterior Lateral Line primordium migration requires interactions between a superficial sheath of motile cells and the skin, 2020, eLife
  • Interphase cell morphology defines the mode, symmetry, and outcome of mitosis, 2025, Science
  • A metabolic shift to glycolysis promotes zebrafish tail regeneration through TGF-β dependent dedifferentiation of notochord cells to form the blastema, 2020, bioRxiv (Cold Spring Harbor Laboratory)

The frequent collaborators of Ajay B. Chitnis include Damian Dalle Nogare, David R. Hoying, Erica Bresciani, Carli D. Needle, and Weiwei Wu. Collaborative efforts have appeared predominantly in the areas of zebrafish biology and related biomedical research.

Best Publications

  • Expression of a Delta homologue in prospective neurons in the chick

    Domingos Henrique;Julie Adam;Anna Myat;Ajay Chitnis

  • Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

    Nathan D. Lawson;Nico Scheer;Van N. Pham;Cheol-Hee Kim

  • Mind Bomb Is a Ubiquitin Ligase that Is Essential for Efficient Activation of Notch Signaling by Delta

    Motoyuki Itoh;Cheol-Hee Kim;Gregory Palardy;Takaya Oda

  • Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta.

    Ajay Chitnis;Domingos Henrique;Julian Lewis;David Ish-Horowicz

  • Repressor activity of Headless/Tcf3 is essential for vertebrate head formation.

    Cheol-Hee Kim;Takaya Oda;Motoyuki Itoh;Di Jiang

  • Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy

    Andrew G York;Sapun H Parekh;Sapun H Parekh;Damian Dalle Nogare;Robert S Fischer

  • Analysis of Upstream Elements in the HuC Promoter Leads to the Establishment of Transgenic Zebrafish with Fluorescent Neurons

    Hae Chul Park;Cheol Hee Kim;Young Ki Bae;Sang Yeob Yeo

  • Instant super-resolution imaging in live cells and embryos via analog image processing

    Andrew G York;Panagiotis Chandris;Damian Dalle Nogare;Jeffrey Head

  • Identification of spinal neurons in the embryonic and larval zebrafish

    Robert R. Bernhardt;Ajay B. Chitnis;Laurie Lindamer;John Y. Kuwada

  • Axonogenesis in the brain of zebrafish embryos.

    Ajay B. Chitnis;John Y. Kuwada

  • Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.

    Bon Kyoung Koo;Hyoung Soo Lim;Ran Song;Mi Jeong Yoon

  • Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons.

    Su Guo;Stephen W. Wilson;Sam Cooke;Ajay B. Chitnis

  • Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy

    Kristin Lorent;Sang Yeob Yeo;Takaya Oda;Settara Chandrasekharappa

  • The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos

    Wui Chuong Jen;Daniel Wettstein;David Turner;Ajay Chitnis

  • Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in Xenopus embryos.

    Ajay Chitnis;Chris Kintner

  • Intralineage Directional Notch Signaling Regulates Self-Renewal and Differentiation of Asymmetrically Dividing Radial Glia

    Zhiqiang Dong;Nan Yang;Sang-Yeob Yeo;Ajay Chitnis

  • Two tcf3 genes cooperate to pattern the zebrafish brain.

    Richard I. Dorsky;Motoyuki Itoh;Randall T. Moon;Ajay Chitnis

  • Zebrafish serotonin N-acetyltransferase-2: marker for development of pineal photoreceptors and circadian clock function.

    Yoav Gothilf;Steven L. Coon;Reiko Toyama;Ajay Chitnis

  • Expression of proneural and neurogenic genes in the zebrafish lateral line primordium correlates with selection of hair cell fate in neuromasts.

    Motoyuki Itoh;Ajay B. Chitnis

  • Fluorescent protein expression driven by her4 regulatory elements reveals the spatiotemporal pattern of Notch signaling in the nervous system of zebrafish embryos.

    Sang-Yeob Yeo;MinJung Kim;Hyung-Seok Kim;Tae-Lin Huh

Frequent Co-Authors

Cheol-Hee Kim
Cheol-Hee Kim Chungnam National University
Chris Kintner
Chris Kintner Salk Institute for Biological Studies
Wolfgang Driever
Wolfgang Driever University of Freiburg
Brant M. Weinstein
Brant M. Weinstein National Institutes of Health
Abdel G. Elkahloun
Abdel G. Elkahloun National Human Genome Research Institute
Julian Lewis
Julian Lewis Cancer Research UK London Research Institute
Settara C. Chandrasekharappa
Settara C. Chandrasekharappa National Institutes of Health
Shawn M. Burgess
Shawn M. Burgess National Institutes of Health
Ted B. Usdin
Ted B. Usdin National Institutes of Health
Anand Swaroop
Anand Swaroop National Institutes of Health

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