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Biology and Biochemistry

D-Index
66
Citations
22087
World Ranking
8488
National Ranking
3817

Overview

Nathan D. Lawson is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cell Biology, Oncology, Neurology, and Cancer Research.

The scientist's work covers several main topics, including:

  • Zebrafish Biomedical Research Applications
  • Angiogenesis and VEGF in Cancer
  • CRISPR and Genetic Engineering
  • Congenital heart defects research
  • Lymphatic System and Diseases
  • Single-cell and spatial transcriptomics
  • Cytomegalovirus and herpesvirus research

Nathan D. Lawson has published numerous papers in high-impact venues, with recent notable publications including:

  • "An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes", 2020, eLife
  • "5'-Modifications improve potency and efficacy of DNA donors for precision genome editing", 2021, eLife
  • "Genomic Characterization of Endothelial Enhancers Reveals a Multifunctional Role for NR2F2 in Regulation of Arteriovenous Gene Expression", 2020, Circulation Research
  • "Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency", 2023, Nucleic Acids Research
  • "VEGFC/FLT4-induced cell-cycle arrest mediates sprouting and differentiation of venous and lymphatic endothelial cells", 2021, Cell Reports

Their frequent co-authors include Masahiro Shin, Scot A. Wolfe, Ann S. Grosse, Yu-Huan Shih, and Daneal Portman. Nathan D. Lawson has contributed to multiple articles published in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Development, Developmental Cell, and Circulation Research.

Best Publications

  • In vivo imaging of embryonic vascular development using transgenic zebrafish.

    Nathan D. Lawson;Brant M. Weinstein

  • ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

    Lihua Julie Zhu;Claude Gazin;Nathan D. Lawson;Herve Pages

  • Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

    Nathan D. Lawson;Nico Scheer;Van N. Pham;Cheol-Hee Kim

  • A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

    Daniel Cifuentes;Huiling Xue;David W. Taylor;Heather Patnode

  • sonic hedgehog and vascular endothelial growth factor Act Upstream of the Notch Pathway during Arterial Endothelial Differentiation

    Nathan D. Lawson;Andreas M. Vogel;Brant M. Weinstein

  • Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

    Xiangdong Meng;Marcus Blaine Noyes;Lihua Julie Zhu;Nathan D. Lawson

  • Recombinant vesicular stomatitis viruses from DNA

    Nathan D. Lawson;Elizabeth A. Stillman;Michael A. Whitt;John K. Rose

  • Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish

    Fatma O. Kok;Masahiro Shin;Chih Wen Ni;Ankit Gupta

  • Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

    Arndt F. Siekmann;Nathan D. Lawson

  • Angiogenic network formation in the developing vertebrate trunk.

    Sumio Isogai;Sumio Isogai;Nathan D. Lawson;Saioa Torrealday;Masaharu Horiguchi

  • MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

    Stefania Nicoli;Clive Standley;Paul Walker;Adam Hurlstone

  • Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels.

    Beth L. Roman;Van N. Pham;Nathan D. Lawson;Magdalena Kulik;Magdalena Kulik

  • Gateway compatible vectors for analysis of gene function in the zebrafish.

    Jacques A. Villefranc;Julio D. Amigo;Nathan D. Lawson

  • Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

    Michael J. Parsons;Harshan Pisharath;Shamila Yusuff;John C. Moore

  • Arteries and veins: making a difference with zebrafish

    Nathan D. Lawson;Brant M. Weinstein

  • Guidelines for morpholino use in zebrafish

    Didier Y. R. Stainier;Erez Raz;Nathan D. Lawson;Stephen C. Ekker

  • Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish

    Laurence D. Covassin;Jacques A. Villefranc;Michael C. Kacergis;Brant M. Weinstein

  • Notch Activity Levels Control the Balance between Quiescence and Recruitment of Adult Neural Stem Cells

    Prisca Chapouton;Paulina Skupien;Birgit Hesl;Marion Coolen

  • phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development

    Nathan D. Lawson;Joshua W. Mugford;Brigid A. Diamond;Brant M. Weinstein

  • A somitic Wnt16/Notch pathway specifies haematopoietic stem cells

    Wilson K. Clements;Albert D. Kim;Karen G. Ong;John C. Moore

Frequent Co-Authors

Brant M. Weinstein
Brant M. Weinstein National Institutes of Health
Lihua Julie Zhu
Lihua Julie Zhu University of Massachusetts Chan Medical School
Scot A. Wolfe
Scot A. Wolfe University of Massachusetts Chan Medical School
Holger Gerhardt
Holger Gerhardt Max Delbrück Center for Molecular Medicine
Didier Y. R. Stainier
Didier Y. R. Stainier Max Planck Society
Christer Betsholtz
Christer Betsholtz Uppsala University
Stefan Schulte-Merker
Stefan Schulte-Merker University of Münster
Cecilia B. Moens
Cecilia B. Moens Fred Hutchinson Cancer Research Center
A. Thomas Look
A. Thomas Look Harvard University

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